Open Access DOI:10.23937/2378-3001/1410082
Changes in Connectivity between Caudate and Frontal Lobe in Patient with Psychosis Induced for Cannabis - Case Report
Hernandez JF, Marin JH, Naranjo L, Rodriguez and Ramirez SF
Article Type: Case Report | First Published: May 16, 2019
The use of marihuana is becoming more frequent in young people, the association between psychosis and cannabis has been described, especially in young people, we present a clinical case of psychosis associated with cannabis in a young man with normal Brain Magnetic resonance, but abnormalities in tractography mainly in the connectivity between cuadate nucleus and frontal lobe. Several longitudinal population studies strongly association between cannabis and psychosis, particularly in individuals...
Open Access DOI:10.23937/2469-5696/1410039
Fatal Systemic Mucormycosis after Rabbit Anti-Thymocyte Globulin Therapy in a Severe Aplastic Anemia Patient
Haruko Tashiro MD, PhD, Yasutoshi Oshima, Ritsu Sumiyoshi, Takuji Matsuo, Tadashi Yamamoto, Kensuke Matsumoto, Jun Ooi, Naohisa Matsunaga, Yoshinao Kikuchi and Naoki Shirafuji
Article Type: Case Report | First Published: May 16, 2019
Survival rates for patients with severe aplastic anemia have greatly improved with the development of better supportive care including transfusion strategies and the availability of anti-fungal agents. However, invasive fungal infection remains the main cause of death and increases mortality in severe aplastic anemia patients. Among invasive fungal infections, mucormycosis is one of the fatal diseases in immunocompromised patients. We report the case of a 72-year-old man with severe aplastic ane...
Open Access DOI:10.23937/2469-5726/1510071
Urinary VCAM-1, KIM-1, and ET-1 as Biomarkers of Lupus Nephritis: Correlation with Immunological Parameters in Hospital USM
Siti Khadijah SM Nazri, BSc, Wan Syamimee W Ghazali, MD, MMed, Noor Suryani M Ashari, MD, MPath and Wan Zuraida WA Hamid, MD, MPath
Article Type: Research Article | First Published: May 15, 2019
So far, there is no conventional parameters that have been proven to possess the ability to predict the histology of systemic lupus erythematosus (SLE). A few autoimmune serology markers of SLE including anti-dsDNA antibodies, complement C3 and C4, and anti-nucleosome could be helpful clinically, but the correlation between those and lupus renal disease is still imperfect. Recently, the urinary vascular cell adhesion molecule-1 (VCAM-1), kidney injury molecule-1 (KIM-1) and endothelin-1 (ET-1) h...
Open Access DOI:10.23937/2572-4061.1510022
Evaluation of Lung Cell Toxicity of Surfactants for Inhalation Route
Lindenberg F, Sichel F, Lechevrel M , Respaud R and Saint-Lorant G
Article Type: Short Communication | First Published: May 15, 2019
Few data are available for excipients administered by inhalation route. This study evaluated the in vitro potential toxicity of three surfactants (Polysorbate 20, Polysorbate 80 and Poloxamer 188) by using an original air-liquid interface (ALI) method of exposure compared to liquid/liquid (L/L) model. Two cell toxicity tests were conducted on BEAS-2B cells, a human immortalized bronchial epithelial cell lines; measurement of Lactate Dehydrogenase activity and XTT cell proliferation assay. We fou...
Open Access DOI:10.23937/2474-3690/1510039
It is Possible that there is a Phenotype of the Metabolic Syndrome in Infants
Fernando Aguirre Palacios
Article Type: Editorial | First Published: May 11, 2019
This editorial is dedicated to obesity, overweight, and sedentarism in infants. The original work was published a few months ago in the Journal of Hypertension and Vascular Risk, with the intention of initiating a global campaign to address the pandemic of obesity from an early age, looking for measurement tools that allow monitoring of intervention programs aimed at reducing it. The intention of the present work was to find the simplest proposal, innovative, and novel, to screen, kids with a hi...
Open Access DOI:10.23937/2469-5750/1510071
Axillary Fox-Fordyce Disease Induced By Laser Hair Removal
Robustelli Test Elisa, Ferreli Caterina, Brundu Maria Angela, Atzori Laura, Pilloni Luca and Rongioletti Franco
Article Type: Case Report | First Published: May 15, 2019
Fox-Fordyce disease (FFD) is an uncommon chronic inflammatory skin disease of the apocrine sweat glands that could be considered as a rare adverse event of laser hair removal. It is postulated that laser therapy could induce damage to the follicular infundibulum, resulting in epidermal detachment and altered keratinocytes maturation which led to keratin plugging. Here, we present a case of a post-pubertal woman who developed axillary itchy lesions with clinical and histological features compatib...
Open Access DOI:10.23937/2572-4010.1510029
Use of Text Messaging as an Intervention to Promote Weight Loss and Reduce Waist Circumference among an Overweight and Abdominally Obese Patient Population: A Randomized-Controlled Quality Improvement Study in Primary Care
Deepa Iyengar, MD, MPH, Michelle R Klawans, MPH, Angela L Stotts, PhD and Thomas F Northrup, PhD
Article Type: Research Article | First Published: May 13, 2019
Obesity is a national epidemic resulting in significant morbidity and mortality. Weight loss as modest as 5% of body weight significantly reduces the risk of hypertension, diabetes, and cardiovascular disease. The primary aim of this pilot study was to test the efficacy of a text messaging intervention in a primary care setting to motivate overweight patients to lose weight and reduce their waist circumference....
Open Access DOI:10.23937/2474-3690/1510038
Nutraceuticals with Blood Pressure Lowering Potential: A Summary of Clinically Relevant Information
Kate Levenberg, David Proctor, Michael Flanagan, Yasina Somani and Faisal Aziz
Article Type: Research Article | First Published: May 11, 2019
Nearly half of patients diagnosed with hypertension are unable to keep their blood pressure under control despite pharmacologic intervention, indicating a need for adjunctive anti-hypertensive therapies. Nutraceuticals may be a promising option for intervention due to their ease of implementation and demonstrated efficacy. The use of nutraceuticals clinically has thus far been limited by a lack of guidelines, likely stemming from a history of poor regulatory standards that allow supplements to g...
Open Access DOI:10.23937/IAMM-2017/1710008
Antimicrobial Properties of the Probiotic Strain Bacillus Subtilis 534
Olga Efremenkova, Nina Gabrielyan, Irina Malanicheva, Mariya Demiankova, Tatiana Efimenko, Eugene Rogozhin, Sofiya Sharapchenko, Tatyana Krupenio, Dmitrij Davydov and Maksim Kornilov
Article Type: Research Article | First Published: May 11, 2019
The object of our research is the transient probiotic strain Bacillus subtilis 534 that is a basis of the drug Sporobacterin. The strain 534 was cultivated in submerged conditions and the obtained culture liquid (CL) was investigated for antimicrobial activity by diffusion into the agar medium method. As test objects, collection strains of bacteria and fungi were used as well as clinical isolates with different resistance to antibiotics. For preliminary chemical characterization, CL was passed t...
Open Access DOI:10.23937/2643-4563/1710012
Hydropneumopericardium: Unusual Complication of Proton Radiotherapy
Nakamura Yasuhiro, MD
Article Type: Clinical Image | First Published: May 13, 2019
Hydropnemopericardium is a very rare condition, which arises from penetrating trauma or blunt chest injury, development secondary to procedures, fistulization from adjacent structures and pericardial infections. This patient was 60-year-old man with hepatocellular carcinoma (HCC) presented to outpatients clinic with stomach pain, fatigue and anorexia. The patient was afebrile but laboratory profile manifested an excessive inflammatory response and disseminated intravascular coagulation. We detec...