Open Access DOI:10.23937/2643-4008/1710009

Upregulation of Single Nucleotide Polymorphism of PD-1 Gene (rs10204525) in Chronic Hepatitis B Patients

Peyman Ghorbani, Hamid Reza Mollaei, Seyed Alimohammad Arabzadeh and Mohammad Javad Zahedi

Article Type: Research Article | First Published: May 29, 2019

Programmed death-1 (PD-1) is major inhibitory molecule that reduces T cell activation. PD-1 and their polymorphisms have separately been shown to be associated with hepatitis B virus (HBV) infection. Therefore, we aimed to investigate the association of PD1 polymorphisms with potential of chronic hepatitis B infection in Iranian population to do a Case-Control study....

 Open Access DOI:10.23937/2643-4555/1710011

Race and Menarche: A Study on Racial Subgroups Living in the West of Iran

Ali Ghanbari, Telka Noormohamadi, Pegah Mirzapur and Mohammad Rasool Khazaei

Article Type: Original Article | First Published: May 25, 2019

Menarche is a physiological phenomenon and significant mile stone in the life of a women and the age at menarche is an indicator of racial, geographical and nutritional patterns of different societies. The aim of present study was to determine the age at menarche in Kermanshah city in the west of Iran focusing on the effect of population racial subgroups living this city....

 Open Access DOI:10.23937/2378-3397/1410101

Vertebral Endplate, Posterior Ligamentous Complex and Neural Dysfunction: Key Factors for Posterior Fusion Strategy in Thoracolumbar Fractures

Mingyong Liu, Liang Zhang, Liangmin Zhang, Jianhua Zhao, Peng Liu, W Fan, X Ying and Y Liu

Article Type: Research Article | First Published: May 25, 2019

The thoracolumbar region (T11 to L2) is more susceptible to injury than other parts of the spine. Approximately 50% of all vertebral body fractures and 40% of all spinal cord injuries occur from T11 to L2. Although basic principles of diagnosis and treatment are established, there are controversies concerning diagnosis and treatment, including classification, indications for surgery and approach, as well as long-or short-segment of fixation and fusion....

 Open Access DOI:10.23937/2378-3656/1410267

Cardiac Lipoma: Diagnosis after Cardiac Arrest

Elaine dos Reis Coutinho, Jose de Arimatea Francisco, Daniele Orrico, Mauricio Lopes Marson, Cleydicion Eloy da Costa, Gustavo Calado de Aguiar Ribeiro, Jose Humberto Pucci de Mesquita Filho, Aloisio Marchi da Rocha and Jose Francisco Kerr Saraiva

Article Type: Case Report | First Published: May 29, 2019

A 24-year-old female patient was admitted to the emergency room with palpitations associated with precordial pain and dyspnea. She was pale, sweating, with the heart rate 220 bpm and blood pressure 80 × 40 mmHg. The ECG demonstrated a sustained ventricular tachycardia rhythm evolving to a ventricular fibrillation rhythm. Four defibrillation attempts were performed with 360 J until obtained to sinus rhythm. ...

 Open Access DOI:10.23937/2378-3656/1410266

Mucosa-Associated Lymphoid Tissue Lymphoma of Thyroid: A Case Report

Youn Joo Jung, Dong-il Kim, Hyun-june Paik, Jeong Hee Lee and Hyun Yul Kim

Article Type: Case Report | First Published: May 29, 2019

Mucosa-associated lymphoid tissue lymphomas are a relatively recently recognized subset of B-cell non-Hodgkin's lymphomas. Generally, mucosa-associated lymphoid tissue lymphomas in the thyroid gland are known to have good prognosis, but recurrence and metastasis have also been reported....

 Open Access DOI:10.23937/2572-3286.1510043

Autophagy and Transforming Growth Factor Beta1 in Renal Tubular Epithelia Cells

Rui Hong Chen, Fen Song, Yu Gan, Ting Ting Li, Lin Ye, Wei Jing Liu and Hua-Feng Liu

Article Type: Review Article | First Published: May 29, 2019

Transforming growth factor beta1 (TGF-β1) is regarded as the important factor in many fibrotic kidney diseases. Autophagy is a vital mechanism which maintains intracellular homeostasis in eukaryotic cells and involves in various renal physiologic and pathological processes. Current studies indicate that autophagy in renal tubular epithelial cells serves as a renoprotective mechanism which modulates the course of diverse kidney disease....

 Open Access DOI:10.23937/2469-5823/1510124

Nurses' Experiences of Health Promotion and Prevention of Cardiovascular Diseases Related to Smoking

Ernelind N, BSN, Wirkensjö H, BSN, Pangastuti HS, BSN, MSc, Perdana M, BSN, MS, Widyawati W, BSN, MPH, PhD and Lepp M, RNT, PhD

Article Type: Original Article | First Published: May 27, 2019

Three themes emerged from the analysis: Conceptions in relation to the patient and their family, conceptions in relation to the hospital and health care centers and conceptions in relation to the culture and policies. All nurses are working with health promotion and prevention of cardiovascular diseases related to smoking in one way or another. However, distinct guidelines and resources are missing....

 Open Access DOI:10.23937/2377-4630/1410090

Current Status of Obstetric Anaesthesia Services (Oasis): A Cross-Sectional Survey of Public Hospitals in Khartoum State, Sudan

Sohel MG Ahmed, Amna Mustafa Ali, Tayseer Salih Mohamed, Mohamed Sayed M Hajnour, Hayat O Elfil, et al.

Article Type: Original Article | First Published: May 27, 2019

Medical services in general, and anaesthetic services in particular, in Sudan have been vulnerable to changes secondary to socio-economic factors over the last few decades. This cross-state survey aims to identify the current set up of obstetric anaesthesia services in 19 hospitals - representing all public hospitals in Khartoum State with maternity units- and audit them against internationally set standards....

 Open Access DOI:10.23937/2377-3634/1410108

The Novel Use of a Group Event for Young Adults with Diabetes to Promote Completion of Essential Diabetes Checks and Diabetes Education

Ravikumar Ravindran, Kofi Obuobie, Sian Ward and Elaine Hibbert Jones

Article Type: Original Article | First Published: May 27, 2019

To use Group learning event as an opportunity to bring young people with diabetes together, improve patient education, peer to peer learning of common themes, assess the satisfaction of the participants with regards to the services being offered and completion of Diabetes annual review checks. The event was conducted in the afternoon over 3 hours with refreshments being offered....

 Open Access DOI:10.23937/2469-5734/1510089

Treatment of Edentulousness by Combined Implantation and Reduced Dentures: A Case Report

Slavoljub Tomić

Article Type: Case Report | First Published: May 27, 2019

Finding the optimal solution for total numbness, which would satisfy all the principles of the modern dental profession, and thus the patient itself, is still a matter of the skills of a surgeon and prosthetist, but also a compromise with the patient, which should in no way compromise with the postulates of dental implantology. This is a presentation of the care of a 65-year-old patient who appeared in a private dental clinic for the solution of total heartlessness, among which the implant-prost...