Open Access DOI:10.23937/2377-3634/1410115
Prevalence of Diabetes Mellitus in Outpatients with Essential Hypertension in a Rural Tertiary Hospital
Ogunmola Olarinde Jeffrey, Ajani Gbadebo Oladimeji and Olabinri Eunice Oluremi
Article Type: Original Article | First Published: December 16, 2019
To determine the prevalence of diabetes mellitus (DM) in patients with essential hypertension attending outpatient medical clinic in a rural community setting of a developing country. This cross-sectional study included patients of a medical outpatient clinic in Federal Teaching Hospital Ido Ekiti, Ekiti State, Nigeria. Study patients were consecutively recruited from Cardiac clinic and baseline investigations obtained from the patients’ files were evaluated including Fasting Blood Glucose (FB...
Open Access DOI:10.23937/2469-5831/1510023
A Signal Detection Analysis of World Health Organization’s Pharmacovigilance Database
Yeqian Liu
Article Type: Original Article | First Published: December 14, 2019
Pharmacovigilance is the primary method used to identify hazards associated with medicinal products. Using generalized likelihood ratio tests, we examed the adverse reaction signals of the drug class Monoamine oxidase inhibitors (MAOIs) from World Health Organization’s Pharmacovigilance Database. The proposed test procedure has the ability of detecting adverse reactions of multiple drugs simultaneously. Our findings sugggest there are 23 common Adverse reaction signals detected within this dru...
Open Access DOI:10.23937/2469-5696/1410046
First Observation of Two TMPRSS6 Gene Mutations (G603R and K636AFSX17) in Turkish Population
Yasemin Ardicoglu Akisin, Gulnaz Kurt, Hüseyin Onay, Ferda Ozkinay and Nejat Akar
Article Type: Case Report | First Published: December 20, 2019
Iron is one of the elements that participate numerous reaction on the body and the structure of hemoglobin to the purpose of carrying oxygen to the tissues. Thus, iron deficiency causes different problems in the body. Iron-refractory iron deficiency anemia (IRIDA) is a genetic disorder that has some signs of iron deficiency anemia (IDA) but refractory to oral iron and partially refractory to intravenous iron. The mutation in TMPRSS6 gene causes matriptase-2 protein deficiency that negatively reg...
Open Access DOI:10.23937/2377-4630/1410100
Perioperative Management of Multiple Intracranial Nail Gun Injuries
Matthew B Ellison, MD, Jeremy Hensley, MD, Roy E Henrickson, MD, Jeffrey Puette, MD, Jason Shepherd, MD, Daniel Sloyer, MD and Pavithra R Ellison, MD
Article Type: Case Rep ort | First Published: January 04, 2020
A 51-year-old male presented to the emergency department with four self-inflicted nail gun wounds. Computed tomography angiography demonstrated three nails penetrating the frontal bone toward the falx cerebri causing small subdural hematomas. The fourth nail penetrated the parietal bone posteriorly, ending very close to the vein of Galen. Despite the ominous-appearing imaging, the patient was neurologically intact and cooperative to the point that consideration was given to the possibility of re...
Open Access DOI:10.23937/2377-4630/1410099
Does Esmolol Havean Effect on Erythrocyte Deformability in Rat Lower Limb Ischemia Reperfusion Injury?
Ali Dogan Dursun, Faruk Metin Comu, Aysegul Kucuk, Ulku Sabuncu, Nevriye Salman, Timucin Sabuncu, Gulay Kip, Omer Kurtipek and Mustafa Arslan
Article Type: Original Article | First Published: December 20, 2019
Ischemia reperfusion (I/R) injury is a common problem in vascular surgery. We aimed to investigate the effects of esmolol on erythrocyte deformability in rat lower limb I/R injury. Following Ethics Commitee approval 24 rats were randomly divided into 4 groups, Control (Group C), Esmolol (Group E), Ischemia-reperfusion (Group I/R), I/R-Esmolol (Group I/R-E). In I/R group, atraumatic microvascular clamp was placed to infrarenal abdominal aorta. After 120 minutes from ischemia, the clamp was remove...
Open Access DOI:10.23937/2469-5742/1510067
Effect, Adverse Events and Re-operations after Tension-free Vaginal Tape Obturator Surgery
Silja Maigaard Axelsen, Rikke Guldberg Sorensen, MD, PhD and Susanne Axelsen, MD, PhD
Article Type: Original Article | First Published: December 18, 2019
Women with stress urinary incontinence can be offered an operation with mid-urethral sling. First, Tension- free vaginal tape was invented. Some years later, because of concerns about complications associated with this operation, the other minimally invasive procedure using the trans obturator procedure was introduced by Dr. J. de Leval in 2003. Since then, the diversity in methods gave rise to a discussion of both efficacy, complications and reoperations. In Denmark, the professional discussion...
Open Access DOI:10.23937/2474-3658/1510102
Tuberculosis Re-Treatment Cases and Factors Associated with Unfavourable Outcome at the Fann University Hospital of Dakar, Senegal between 2011 and 2016: A Follow-Up Study
Viviane Marie Pierre Cisse Diallo, Louise Fortes Deguenonvo, Aminata Massaly, Ndeye Aissatou Lakhe, Daye Ka, Khardiata Diallo M Baye, Ndeye Fatou Ngom Gueye, Assane Diouf, Farah Djamal Waberi, Alassane Dieye, Ndeye Maguette Fall, Cheikh Tacko Diop, Cheikh Tidiane Ndour, Sylvie Diop Nyafouna, Masserigne Soumare and Moussa Seydi
Article Type: Research Article | First Published: December 09, 2019
The aim of our study was to describe the socio-demographic, clinical, therapeutic and evolutionary characteristics of patients admitted to tuberculosis re-treatment and managed at the The Infectious and Tropical Diseases Department (SMIT) screening and tuberculosis treatment center (TTC), to determine the factors associated with unfavourable outcome. This is a descriptive and analytical retrospective cross sectional study covering all tuberculosis re-treatment cases monitored in the service of i...
Open Access DOI:10.23937/2474-3658/1510101
Histopathologic Detection and Identification of Infectious Agents in Granulomatous Inflammation: Comparison with Culture
Sarah Hackman, MD and Daniel D Mais, MD
Article Type: Original Article | First Published: December 09, 2019
Granulomas in surgical specimens, especially within lung and lymph nodes, commonly have an infectious etiology. Granulomatous tissue is usually sent to both surgical pathology for tissue examination and to clinical microbiology laboratories for culture. We performed a retrospective review and comparison of histochemical stains and clinical microbiology culture results in 132 surgical pathology granuloma specimens to determine the utility of tissue morphological examination for detection and iden...