Open Access DOI:10.23937/2474-3658/1510324
The Role of Microbiome in Malaria Transmission and Severity
Kwame Kumi Asare and Paul Ekow Duntu
Article Type: Review Article | Publication Updated: 2024/07/10
Malaria is a public health concern, especially in Sub-Saharan Africa. Several malaria control programs to treat, control, and eradicate malaria have been implemented, however, more than 90% of malaria-related deaths in under five years occur in Africa. With the emergence and spread of artemisinin-resistant P. falciparum, global malaria control now focuses on vaccine development and a search for novel and efficient antimalarial drugs. Although current evidence shows host microbiota play a signifi...
Open Access DOI:10.23937/2469-5807/1510154
The Role of Cell Cycle Division 6 (CDC6) in Cancer: Breast Cancer as a Prototype
Yousif A Kariri
Article Type: Review Article | Publication Updated: 2024/07/08
An increase in cancer-cell division (proliferation) is a distinctive feature of cancer and is acknowledge as a key cell-division checkpoint alteration in cancer cells. Breast cancer is well-known as a heterogeneous disease with variant molecular subtypes, responses to therapy and morphological characteristics, breast malignant cells are identified to deactivate cell-cycle checkpoints to support survival and proliferation. Cell-cycle division 6 (CDC6) plays an important role as a cell-cycle check...
Open Access DOI:10.23937/2378-3419/1410187
Plasma Cell Neoplasms with Atypical Features in a University Hospital
Everard Kylie R, MD, Zern Chantel, MD and Ikpatt Offiong Francis, MD
Article Type: Review/Case Series | Publication Updated: 2024/07/08
Plasma cell neoplasms are derived from terminally differentiated B-cells. The distinction between anaplastic plasma cell myeloma and plasmablastic lymphoma, a B cell lymphoma, can be challenging. We present 3 cases of neoplasms with plasmacytic features that highlight the heterogeneity of plasma cell neoplasms and challenges in their diagnosis. Molecular profiling of these cases may provide value in their differential diagnosis....
Open Access DOI:10.23937/2643-461X/1710077
Neonatal Anemia: Prevalence, Associated Factors, and Impact of Malaria in a Newborn Population at the University Hospital Center of Libreville
Minko J, Mbang Nguema OA, Moutombi Ditombi B, Lembet Mikolo AM, Ovengue FC, Mawili Mboumba DP, Ategbo SJ and Bouyou-Akotet MK
Article Type: Research Article | Publication Updated: 2024/07/07
Demographic, clinical, and paraclinical variables of the newborns, as well as maternal histories were prospectively collected in 2015. A thick drop and a complete blood count were performed....
Open Access DOI:10.23937/2474-3658/1510323
Knowledge, Attitudes, and Practices of Healthcare Students' Infection Control in COVID-19 Test Sampling in Vietnam: A Cross-Sectional Descriptive Study
Khanh Hoang Pham, Quyen Thi My Huynh, Ny Dang Tieu Tran, Phuong Truc Vo, Nhat Minh Phan, Tuong Manh Do, Thi Anh Nguyen, Karl Rennick-Zuefle and Tin Hoang Nguyen
Article Type: Research article | Publication Updated: 2024/06/30
The Coronavirus Disease 2019 (COVID-19) pandemic became much more severe in 2021. Healthcare students were a crucial population that needs to participate in disease preventive assistance and were very susceptible to COVID-19 exposure due to the specialized nature of their area of study. Knowledge, attitudes, and practices were important for protecting healthcare volunteer students against infection in COVID-19 sampling....
Open Access DOI:10.23937/2643-4474/1710161
CNS Embryonal Tumour with Desmoplastic Reaction Treated with Ultra-NPT Bionanocatalysts
Tessy Lopez-Goerne, Francisco J Padilla-Godínez, Daniel Alvárez-Amador, Antonela Gonzalez-Bondani, Rafael Valiente, Fernando Chico Ponce de Leon, Vicente Gonzalez-Carranza and José Omar Navarro-Fernández
Article Type: Case Report | Publication Updated: 2024/07/06
Central nervous system (CNS) embryonal tumors, lacking a distinct molecular signature and categorized as "Not Otherwise Specified (NOS)", are WHO grade IV neoplasms with significant genetic diversity. They typically exhibit immature cell sheets with round, oval, or angulated nuclei, often located supratentorially and characterized by a desmoplastic reaction. Diagnosis relies on MRI and molecular analysis, with traditional management involving surgery, radiotherapy, and chemotherapy. However, rec...
Open Access DOI:10.23937/2474-1353/1510162
Longitudinal Analysis of Heart Rate Variability in Post-Bariatric Pregnant Woman: A Case Report
Renata da Silva Cardoso Rocha Tavares, PhD, Tatiana Sousa Cunha, PhD and Karina Rabello Casali, PhD
Article Type: Case Report | Publication Updated: 2024/06/30
The measurement of heart rate variability (HRV) allows a noninvasive investigation of the functioning of the autonomic nervous system, especially the balance between sympathetic and vagal activity. Pregnancy after bariatric surgery has some peculiarities that may interfere with its course and evolution. Studies have investigated the variability of maternal heart rate and its relationship to the prognosis for pregnancy development about the risks of eclampsia and pregnancy complications. This pap...