Open Access DOI:10.23937/2469-5831/1510024
Nonparametric Method for Estimation of Controlled Correlations in Studies of VEGF-Hypoxia Relationship
Maxim S Kodryan, Anna V Kuznetsova, Luidmila L Klimenko, Aksana N Mazilina, Ivan V Baskakov and Oleg V Senko
Article Type: Research Article | First Published: March 04, 2020
It is known that vascular endothelial growth factor (VEGF) expression is a response to hypoxia. On the other hand hypoxia may be detected by oximetry parameters including venous CO-oximetry indices or corresponding partial pressures of O2 and CO2. However significant correlation ties between VEGF levels and oximetry parameters were not found in groups of patients with ischemic stroke and transient ischemic attack. At that some effect related to the relationship between VEGF and sO2 was observed ...
Open Access DOI:10.23937/2377-9004/1410163
Urinary Retention in The Case of a Retroverted Uterus in Pregnancy
Camille A Clare, MD, MPH
Article Type: Case Report | First Published: April 08, 2020
Acute urinary retention in patients with retroverted uteri is a rare, obstetrical emergency, and requires immediate intervention. If not treated, it may lead to serious maternal and/or fetal complications. This manuscript describes the case of a 35-year-old female who presents with lower abdominal pain and urinary hesitancy. Physical examination noted a palpable urinary bladder, which was also distended on pelvic ultrasound. Obstetrical ultrasound noted a viable intrauterine pregnancy. The patie...
Open Access DOI:10.23937/2377-9004/1410162
Surgical Management of a Juvenile Cystic Adenomyoma: A Unique Presentation of Adenomyosis
Huda Afaneh, MD, Karen Moses, MD, Omari Young, MD and Mostafa Abuzeid, MD, FACOG, FRCOG
Article Type: Case Report | First Published: April 03, 2020
Endometriosis is characterized by the presence of endometrial glands and stroma in ectopic locations within the peritoneal cavity. More commonly, the lesions can be found on areas such as the cul-de-sac and other pelvic parietal surfaces. Endometrial glands and stroma infiltrating the myometrium characterizes Adenomyosis. Adenomyosis is usually characterized by diffuse foci of endometrial glands scattered throughout the myometrium. Meanwhile, a less common type of adenomyosis, in which the lesio...
Open Access DOI:10.23937/2378-346X/1410113
Resolution of Intraocular Lens Precipitates with Topical Corticosteroids
Tanner J Ferguson, MD, Jordan D Deaner, MD, Craig See, MD, and Careen Y Lowder, MD, PhD
Article Type: Case Report | First Published: March 30, 2020
We describe a case of a patient who developed late-onset intraocular lens (IOL) cellular precipitates 8 months after IOL placement. The patient had a history of clinically inactive toxoplasmosis and developed visually significant IOL precipitates 8 months after uncomplicated cataract surgery with a previously unremarkable postoperative course without other signs of ocular inflammation. The IOL deposits improved and resolved with use of topical steroids, which coincided with an improvement in vis...
Open Access DOI:10.23937/2378-2951/1410169
Non-Bacterial Thrombotic (Marantic) Endocarditis of the Aortic Valve: A Rare Cause of STEMI Revealing a Polycythemia
Judit Ozse , Rainer Knur and Nicolas Von Beckerath
Article Type: Case report | First Published: March 24, 2020
Acute myocardial infarction is a major cause of death and disability worldwide. In general 4% to 7% of all patients diagnosed with AMI do not have coronary artery disease (CAD) at coronary angiography or autopsy. Embolisation as a mechanism of myocardial infarction is well known. Large diversity of aetiologies makes the precise diagnosis challenging. Its sources can be thrombi from left sided heart cavities, paradoxal embolism, tumors (myxoma, fibroelastoma), endocarditis (infective or nonbacter...
Open Access DOI:10.23937/2643-4466/1710023
Stress from Uncertainty Predicts Resilience and Engagement among Subspecialty Medicine Fellows
Arabella L Simpkin, MD, MMSc, Susan Hata, MD, Merranda Logan, MD, MPH and Katrina A Armstrong, MD, MSCE
Article Type: Research Article | First Published: March 28, 2020
Burnout is an accelerating phenomenon in the healthcare environment, with implications for physician wellbeing, patient safety, and the quality of healthcare. The ability to manage uncertainty has been identified as a potentially important determinant of burnout in physicians and is now a recognized competency for trainees. No prior studies have evaluated the association of fellows’ reaction to uncertainty with burnout metrics, including resilience and engagement. Cross-sectional online survey...
Open Access DOI:10.23937/2378-3397/1410109
A Successful Surgical Treatment of Postoperative Hepato-Venous Fistula
Toshimitsu Iwasaki, Masataka Matsumoto, Shumpei Satoi, Yuta Yoshida, Kohei Kawaguchi, Keiko Kamei, Atsushi Takebe, Ippei Matsumoto, Takuya Nakai and Yoshifumi Takeyama
Article Type: Case Report | First Published: April 03, 2020
A 72-year-old man, who had been received hemodialysis for chronic kidney disease, underwent resection of hepatic bed and hepatocholedochus with satellite lymphadenectomy for incidentally identified gallbladder carcinoma after laparoscopic cholecystectomy. He developed spike fever on postoperative day (POD) 10. Computed tomography (CT) showed small fluid collection around the resection surface of liver (Figure 1). Percutaneous drainage was performed and a little fluid with serous appearance was g...
Open Access DOI:10.23937/2378-3516/1410131
Classification Models of Idiopathic Pulmonary Fibrosis Patients
Mohammed Alqawba, Luis R Rodriguez, Norou Diawara, Rebecca T Beuschel, Maryann Kaler, Amisha V Barochia, Stewart J Levine, Steven D Nathan and Geraldine Grant
Article Type: Research Article | First Published: March 16, 2020
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal interstitial lung disease with no current cure. Progression of IPF is difficult to predict as the clinical course can be highly variable and range from a rapidly deteriorating state to a relatively stable state, or may be characterized by a slow progressive decline. Therefore, the need for an accurate diagnosis and improved tools for monitoring and managing IPF is of paramount importance, all for understanding the mitochondrial structure...
Open Access DOI:10.23937/2469-5807/1510105
Extrarenal Rhabdoid Tumour of Soft Tissue
Herbert Plasschaert, Frederik Deman, Isabelle Vanden Bempt, Veerle Labarque, Michael Aertsen, Hilde Brems and Raf Sciot
Article Type: Case Report | First Published: March 14, 2020
Extrarenal rhabdoid tumours appearing in the soft tissues are very rare and might be confused with other high-grade sarcomas harbouring rhabdoid features. We present a case and highlight the differential diagnosis, the ancillary techniques necessary to define its true rhabdoid nature, and the existence of hereditary syndromes. Our case concerns a new-born boy with a congenital and rapidly growing mass in the soft tissue of the left thoracic wall, expanding from a few cm in diameter at the time o...