Open Access DOI:10.23937/2474-3690/1510046

Prevalence of Hypertension among Rural Adults and Availability of Management Services in a Nigeria Community

Ojima Zechariah Wada, David B Olawade, Temitope D Afolalu, Awe O Oluwatofarati and Iyanuoluwa G Akinwalere

Article Type: Research Article | First Published: April 11, 2020

With over a billion people across the globe living with hypertension and over a tenth of the global annual mortality being attributed to hypertension, it is no surprise why this disease is of great public health concern. In the bid to reduce the prevalence of hypertension by 25% by the year 2025, recent data about the current prevalence and disparities in health intervention is required. This study provides relevant information about the prevalence of hypertension in a distant rural community in...

 Open Access DOI:10.23937/2469-5858/1510087

The Predictive Status of the Neurocognitive Frailty Index in a Canadian Sample of Elderly with Hypertension

Sarah Pakzad, Paul Bourque and Nader Fallah

Article Type: Research Article | First Published: April 03, 2020

According to Statistics Canada in 2014, 23.4% of Canadians aged between 45 and 64-years-old, and 47, 4% of adults aged 65 years and older were diagnosed with hypertension. Given the significant association between hypertension and cognitive decline, and consequently on frailty status, the contribution of Neurocognitive Frailty Index in the assessment of patient’s prognosis is of utmost importance. Hence, the prognostic utility of the Neurocognitive Frailty Index (NFI), a comprehensive measure ...

 Open Access DOI:10.23937/2469-5750/1510079

One Case of Refractory Condyloma Acuminatum in Children with Persistent HPV51 Infection Treated By Chinese Medicine Paiteling

Yang Meng, Huang Yaohui, Zhu Qinghuan, Lin Xiujuan, Pan Yanbin and Li Jianmin

Article Type: Case Report | First Published: March 30, 2020

Condyloma acuminata (CA), or anogenital verrucae, is a common sexually transmitted disease associated with human papilloma virus infection. It is principally transmitted through sexual intercourse and frequently occur in adolescents or adults. In the last decades, cases of CA in children gradually have increased that may be related to sexual abuse, vertical transmission and close contact with infected individuals. Guidelines...

 Open Access DOI:10.23937/2469-584X/1510072

A Role for Pre-Polymerized Sucralfate in the Management of Erosive and Non-Erosive Gastroesophageal Reflux Disease

Ricky Wayne McCullough, MD, ScM, FAcadTM

Article Type: Review Article | First Published: March 30, 2020

Clinical outcomes from standard sucralfate do not justify role in the management of erosive and non-erosive gastroesophageal reflux disease. Pre-polymerized sucralfate, sometimes called high potency sucralfate or polymerized cross-linked sucralfate is a new sucralfate formulation recognized by the US FDA in 2005. Positive clinical data from three randomized controlled trials using pre-polymerized sucralfate for GERD and NERD was first reported in 2014 AGA’s Digestive Disease Week (DDW)....

 Open Access DOI:10.23937/2474-1353/1510113

Delaying Antibiotics: A Cause for the Rise in Morbidity and Mortality from Sepsis?

John L Yovich, MD

Article Type: Commentary | First Published: April 08, 2020

A recent report analyzing the global burden of disease shows that the incidence and mortality from severe sepsis has continued to rise across the period 1990-2017. Although the burden is highest among low-income countries, there are more than 5 million deaths recorded annually in high-income countries and this burden is disproportionately high among young persons, being mostly from communicable infections. Despite residing in one of those high-income countries, I have witnessed severe morbiditie...

 Open Access DOI:10.23937/2469-567X/1510060

Dual Carriage of Hepatitis B Surface and Hepatitis B Envelope Antigen in Children in a Tertiary Health Facility in the Poorest Region of Nigeria, 2000-2015

Isaac Warnow Elon, Jalo Iliya, Alkali Yaya, Ajani Ayomikun, Abubakar Joshua Difa, Oyeniyi C and Danlami Halilu

Article Type: original research | First Published: April 10, 2020

Hepatitis B infection is endemic in sub-Saharan Africa, where transmission predominantly occurs in infants and children by perinatal and horizontal routes. The risk of chronic infection peaks when infection is acquired early. Records of Hepatitis B surface and envelope antigen results in Federal Teaching Hospital, Gombe between May 2000 and May 2015 were retrieved and analyzed. Hepatitis B surface antigen is high among adolescent males. Infants and young children have the highest carriage rate ...

 Open Access DOI:10.23937/2643-461X/1710029

A Prospective Analysis of Otomycosis in a Tertiary Care Hospital

Shuaib Kayode Aremu, Kayode Rasaq Adewoye and Tayo Ibrahim

Article Type: Original article | First Published: April 08, 2020

The study was conducted in the Ear, Nose, and Throat (ENT) department of Federal Teaching Hospital Ido-Ekiti, which is a tertiary care hospital in Ekiti state, Nigeria. The study involved 275 patients above the age of 10, who presented in the ENT department over 5 years period and were clinically diagnosed cases of otomycosis. Certain patient demographics such as age, gender, and clinical presentations were recorded along with possible risk factors and clinically observed findings. Microbiologic...

 Open Access DOI:10.23937/2469-5769/1510060

Impact of Low Grade Periventricular-Intraventricular Hemorrhage on Neurodevelopmental Outcome of Preterm Infants

Atef Alshafei, MRCPCH. MSc

Article Type: Review article | First Published: April 09, 2020

Improvement of neonatal intensive care in the modern era has greatly changed the demographic image with evolving new generation of extreme preterm survivors. And indeed, evolving new co-morbidities that influence the short and long-term outcomes of these infants. Periventricular-Intraventricular hemorrhage (PVH-IVH) is a significant health problem affecting the brain structures in a critical stage of development in preterm infants. Although the incidence has declined since the 80's of the last c...

 Open Access DOI:10.23937/2378-346X/1410114

Neurodevelopmental Disabilities in Children with Retinopathy of Prematurity: A Report from India

Nagamani Beligere, MD, MPH, Vijayalakshmi Perumalsamy, MD, Jeyaseeli H Flora, MS and Marla J Garska, MS

Article Type: Research Article | First Published: March 30, 2020

We assessed the neurodevelopment, visual and neurological outcomes among children with a diagnosis of ROP referred to an ophthalmic center in India between 2014-2016. Neurodevelopmental status was assessed using skills inventory, for premature and primary school children who are blind and visually impaired. Visual and motor coordination status was assessed using Buketencia Developmental Test of Visual Motor Integration....

 Open Access DOI:10.23937/2377-3634/1410118

Serum Trypsinogen and Lipase as Biomarkers of Exocrine Pancreatic Function in Newly Diagnosed Children and Adolescents with Type 1 Diabetes Mellitus

Eman M Sherif, MD, Doaa M A Elzoghby, MD and Rasha Eladawy, MD

Article Type: Research Article | First Published: March 30, 2020

Type 1 diabetes mellitus (T1DM) in literature has usually been associated with laboratory decrease in pancreatic exocrine enzymes levels. Nevertheless, the exact onset of decreased pancreatic enzymes levels in sera of patients is still unknown. We measured pancreatic serum levels of trypsinogen and lipase in Egyptian children and adolescents with newly diagnosed T1DM to reveal their role in diagnosis and their relation to HbA1c as a marker of glycemic control, lipid profile and fasting c-peptide...