Open Access DOI:10.23937/2378-3001/1410098
Blood Blister-Like Aneurysm of the Intracranial Internal Carotid Artery Associated With Extracranial Dissection of the Artery
Riccardo Russo, Fabrizio Venturi, Mauro Bergui and Gianni Boris Bradac
Article Type: Case Report | First Published: April 23, 2020
Blood blister-like aneurysms (BBAs) have been described as small aneurysmal bulges, more frequently arising from non-branching sites on the supra-clinoid internal carotid artery (ICA). Their etiology is still controversial. In our case the association of the BBA, presenting with a severe subarachnoid bleeding, and extracranial ipsilateral ICA dissection in a patient with fibromuscular dysplasia, could suggest that both lesions were due to the same pathologic process. The aneurysm was treated in ...
Open Access DOI:10.23937/2378-3672/1410046
An Immunological Algorithm to Defeat Covid-19
Ajay Gupta and Ayush Gupta
Article Type: Commentaries | First Published: April 27, 2020
Countries like Italy, Spain or Germany etc. with very low prevalence of tuberculosis and discontinued BCG immunization since decades, are witnessing the worst form of this global pandemic of Corona virus. It has also been seen that Covid-19 affected more of those countries who have robust and free influenza vaccination programme. High mortality of Covid-19 patients is probably result of the reduced Th1 immunity due to lack of past exposures to various infections and poor or absent local innate i...
Open Access DOI:10.23937/2378-3672/1410045
Blood Plasma from Survivors of COVID-19: A Novel and Next Frontier Approach to Fight against Pandemic Coronavirus
Nimesh Singh and Archana Pandey
Article Type: Review Article | First Published: April 26, 2020
Blood from people who have recovered can be a rich source of antibodies, proteins made by the immune system to attack the virus. The part of the blood that contains antibodies, so-called convalescent plasma, has been used for decades to treat infectious diseases, including Ebola and influenza. In the absence of a cure or vaccine for the coronavirus, a group of scientists is searching for a fast solution in an unconventional place: The veins of people who have recovered. Starting in New York City...
Open Access DOI:10.23937/2643-3885/1710043
Examination of Rear Foot Bones Shapes in Patients with Ankle Osteoarthritis using Principal Component Analysis
Takuya FUJINUMA, Yuya OISHI, Shinichi KOSUGI, Hiroaki KUROKAWA, Yasuhito TANAKA, Satoki TSUICHIHARA and Hiroshi TAKEMURA
Article Type: Research Article | First Published: April 22, 2020
Artificial ankle joint replacement surgery is an important treatment for patients with ankle osteoarthritis (OA). Estimation of the pre-deformed ankle bones shapes are a key factor in artificial joint replacement surgery, and the surgeon can achieve highly satisfactory outcomes for patients such as less pain and sufficient function with an alternative ankle joint. However, the relationship between the bone shape deformation process and stage of the disease remains unclear. In this study, we inve...
Open Access DOI:10.23937/2377-3634/1410119
Evaluation of Corneal Transparency in Diabetic Patients Aged 60 Years and Over
Luling Yang and Xuemin Li
Article Type: Original Article | First Published: April 16, 2020
The corneal densitometry analysis results varied between different age groups. In the 60 to 69 age group, the anterior layer at zone 0 to 2 mm had better corneal clarity in controls than in DM patients. Corneal densitometry values were markedly higher in diabetic eyes compared with control eyes in 70 to 79 age group when considered by central zones of total cornea at the 2 to 6 mm. The corneal transparency increased in 80 to 89 years DM patients in the majority of corneal zones. Besides, a weak ...
Open Access DOI:10.23937/2378-3419/1410135
Haemoheological Studies in Cancer - Future Scope
Amit Sengupta, MBBS, MD, PhD
Article Type: Short Communication | First Published: April 23, 2020
Hyper-viscosity of blood was documented in cancer. A marginal fall in the blood viscosity was noted during treatment. In some patients, a significant fall in the viscosity, hematocrit and plasma protein level was observed. We noted no post-treatment survival benefit in them. The fall in viscosity was possibly linked to lowering of immunological factors, anti-inflammatory response, reduction in cancer cell density and also serum proteins and hematocrit. We need to conduct well designed studies in...
Open Access DOI:10.23937/2378-3419/1410134
Extracutaneous Melanoma: About Five Observations and Review of the Literature
Khadija Elboukhari, Kaoutar Achehboune, Sara Elloudi, Hanane Baybay, Nawal Hammas, Leila Chbani and Fatima Zahra Mernissi
Article Type: Case Series | First Published: April 16, 2020
Extracutaneous melanoma is not a frequent situation, making a difficulty for the diagnosis. It is characterized by a poorer prognosis and rapid metastasis. The research for a primitive cutaneous melanoma is obligatory before retaining this entity. The dermatologist role is to eliminate a cutaneous primitive melanoma by the clinic and dermoscopic examination. We report five cases of non-cutaneous melanoma: Three mucosal melanoma, one choridian, and the fifth one is a parotid melanoma, and we will...
Open Access DOI:10.23937/2378-2951/1410174
Covid-19 and the Cardiologist!
Sharma Prachi, MD, DNB, Sethi Rishi , MD, DM, FACC, FESC, FRCP (Edin.), FCSAI, FAPSIC, MAMS, FCSI, FISC and V S Narain, MD, DM, FSCAI, FESC
Article Type: Commentary | First Published: April 29, 2020
While the world is badly hit by this SARS-CoV-2 pandemic, the cardiologists have a special role to play and risks too to bear. Patients with known cardiovascular diseases are at a risk of increased morbidity and mortality by this infection. Also, Covid-19 may present with varied cardiovascular manifestations. This puts the upfront managing cardiologist and his team at greater risk of catching infection. So, they need to find the best possible way to help such patients with minimum possible risk ...
Open Access DOI:10.23937/2378-2951/1410173
National Trends and Outcomes of Myocardial Infarction: Result from National Inpatient Sample 2000 to 2015
Abdulrahman S Museedi, MD, Mouhamed Nashawi, BS, Abdullah Ghali, BS, Aws Alameri, MD, Mustafa Al Qaysi, MD and Robert Nathanson, MD, FACP
Article Type: Observational study | First Published: April 20, 2020
The burden of cardiovascular disease within the United States is profound, with large volumes of economic and academic resources being utilized to treat patients with cardiovascular diseases. Myocardial infarctions (MI) represent one of the most acute forms of cardiovascular pathology, with a profound mortality rate if prompt treatment and medical attention is not sought out after. While elements of changes in clinical practice and the spurring of new guidelines are responsible for improved heal...