Open Access DOI:10.23937/2572-407X.151040

Adequate 25-OH-Vitamin D Level and Calcium Intake Enhance the Efficacy of Teriparatide in Gain-of-Function Mutation in Calcium-Sensing Receptor Defect, A Case Report

Ho Man Tong and Lap Ming Wong

Article Type: Case Report | First Published: August 11, 2025

Gain-of-function mutations in the calcium-sensing receptor (CaSR) result in congenital hypoparathyroidism, characterized by suppressed parathyroid hormone (PTH) secretion, hypocalcemia, hyperphosphatemia and hypercalciuria. Managing hypocalcemia in these patients is challenging, as conventional therapy with calcium and active vitamin D analog supplementation often exacerbates renal complications....

 Open Access DOI:10.23937/2572-3235.1510136

Best Methods to Reduce Unnecessary Radiation Exposure

Liliana Ramirez

Article Type: Literature Review | First Published: July 29, 2025

The role of a radiographer is to create diagnostic quality images using different forms of radiation. Radiography uses x-rays to create radiographic images, which can cause biochemical changes. It is the ethical and legal responsibility of a radiographer to follow radiation protection practices and the concept of ALARA, as low as reasonably achievable, and protect the patient from unnecessary radiation....

 Open Access DOI:10.23937/2377-3634/1410187

Validation of the Ipswich Touch Test for Screening of Loss of Protective Sensation and Peripheral Neuropathy in Type II Diabetes

Zairul Nizam Z Fithri, Lokman H Sulaiman, Ida S Ismail, Normy Narihan, Shamini Nadaraja and Adila Selamat

Article Type: Original Article | First Published: July 25, 2025

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes that significantly increases the risk of foot ulceration and amputation. Early detection of loss of protective sensation (LOPS) is critical, particularly in resource-limited settings. This study aimed to validate the Ipswich Touch Test (IpTT), a simple and non-invasive screening tool, against the 10 g monofilament (MF) and other neurological assessments in individuals with Type II diabetes....

 Open Access DOI:10.23937/2643-4512/1710102

Pulmonary Hypertension in Pediatric and Adult Congenital Heart Disease: Deciding When and When Not To Repair. An Overall Perspective of Latin America and the Caribbean Countries

John J. Araujo, MD, MBBS, NBE, FSIAC, FSISIAC, FACC, FASE

Article Type: Review Article | First Published: July 22, 2025

Congenital heart defects are very prevalent in the world, affecting 1 out of 100 live births. In Latin America and the Caribbean, more than 57,000 children are born with a congenital heart defect each year, 45% of which are moderately and highly complex. Globally, 6-8% of congenital heart defects may develop pulmonary hypertension and, of these, 50% will develop the most extreme form, Eisenmenger syndrome....

 Open Access DOI:10.23937/2469-5769/1510138

Risk Factors for Death in Premature Newborns at the Ouahigouya Regional Teaching Hospital in Burkina Faso

Ouermi AS, Sanogo B2, Savadogo H, Ouattara ABI, Some Z, Barro M and Yugbare S

Article Type: Original Article | First Published: July 08, 2025

Prematurity is a real public health problem in developing countries. The objective of this study was to investigate the risk factors for death in premature newborns in a pediatric ward. This was a retrospective cross-sectional study with descriptive and analytical aims that took place over a period of 12 months....

 Open Access DOI:10.23937/2572-4215.1510034

Statin-Associated Immune-Mediated Necrotizing Myopathy: A Case Report

Emily Andrews, OMS-IV, Graham McDaniel, MD and Haiping Mei, MD

Article Type: Case Report | First Published: June 21, 2025

Statins are a widely used class of drugs that have been found to be safe and effective in treating hypercholesterolemia. Statin-associated muscle symptoms (SAMS) are a clinical spectrum defined as muscle pain, discomfort, and/or weakness with or without elevated CK levels. This spectrum ranges from more common minimal myalgias to rare, severe statin-associated immune-mediated necrotizing myopathy (IMNM)....

 Open Access DOI:10.23937/2469-5750/1510132

Dermatologic Lasers: Comprehensive Review of Cosmetic and Therapeutic Uses

Emily H. Miller

Article Type: Literature Review | First Published: July 22, 2025

Laser and light therapy for dermatology has revolutionized the practice of dermatology to offer highly accurate, effective therapies for a wide range of skin conditions. This article provides a comprehensive description of dermatologic lasers, covering their history, mechanism of action, classification, application, and relative efficacy....

 Open Access DOI:10.23937/2469-5750/1510131

Use of Verteporfin to Regrow Hair and Reduce Fibrosis after Transplantation

Melissa Toyos, MD, Rolando Toyos, MD, Allison Toyos

Article Type: Review Article | First Published: July 22, 2025

Verteporfin is FDA-approved for wet macular degeneration. Recent Stanford research has revealed a novel use for verteporfin promoting scarless skin regeneration by inhibition of Yes-associated protein (YAP), preventing the activation of En1-positive fibroblasts causing scars....

 Open Access DOI:10.23937/2378-346X/1410162

Adult-Onset Orbital Xanthogranuloma Presenting As A Chronic Painless Upper Eyelid Mass

Catherine Y Liu, Lea Carter, and Jorge Agi

Article Type: Original Article | First Published: July 15, 2025

Imaging revealed a well-circumscribed, enhancing intraconal mass, and histopathological examination following orbitotomy confirmed xanthogranulomatous inflammation. Stains for infectious organisms were negative, and no systemic abnormalities were identified, supporting a diagnosis of isolated AOX. Although the patient experienced transient improvement with corticosteroids, definitive management required surgical excision....

 Open Access DOI:10.23937/2378-3397/1410178

Incidental Finding of Situs Inversus Totalis in Cadaveric Kidney Transplant Donor: Surgical Challenge and Short-Term Evolution of Recipients

Jennifer Hernandez Licona, Jesus Bravo Leon, Veronica Gonzalez Mascareno and Jesus Antonio Martin Hernandez

Article Type: Case Report | First Published: July 22, 2025

Kidney transplantation is the treatment of choice for patients with end-stage chronic kidney disease. In the first six months post-transplantation, surgical complications represent a significant cause of graft loss. Situs Inversus Totalis (SIT) is a rare anatomical anomaly that poses technical challenges in organ procurement and transplantation. Evidence regarding the viability of organs from donors with SIT is scarce....