Open Access DOI:10.23937/2378-3397/1410112

Acute Cholecystitis as an Unusual Cause of Abdominal Wall Abscess

Mehdi Hammemi, Wael Ferjaoui, Ghofrane Talbi and Mohamed Taher Khalfallah

Article Type: Surgical Image | First Published: June 29, 2020

It is about a 68-year-old woman who presented to the emergency department with a painful inflammatory swelling in the right upper abdomen and the epigastrium since 6 days. She had a medical history of obesity and type 2 diabetes. She had no surgical history. At physical examination, there is no fever with tenderness in the right upper quadrant of the abdomen. She presented a lump in the right upper abdomen and the epigastrium measured 5 × 6 cm which is red and painful. Laboratory data showed wh...

 Open Access DOI:10.23937/2469-570X/1410069

Stembell Therapy Reduces Macrophages in Atherosclerotic Aortic Valves after Myocardial Infarction

Amber van Broekhoven, MD, Linde Woudstra, PhD, Elisa Meinster, Laura van Haren, Amber M Kay, Marit Koopman, Martine C Morrison, PhD, Marco N Helder, MD, PhD, Lynda J Juffermans, PhD, Casper G Schalkwijk, PhD, Hans WM Niessen, MD, PhD, Alexander BA Vonk, MD, PhD and Paul AJ Krijnen, PhD

Article Type: Original Research | First Published: July 08, 2020

Previously, we have shown that StemBell therapy (i.e. mesenchymal stem cell-microbubble complexes subjected to ultrasound) reduced plaque inflammation and plaque destabilization in the aortic root, and thereby inhibited atherosclerosis exacerbation after myocardial infarction (MI). MI also has an effect on heart valves as it increases valve thickness and remodeling. Moreover, hemodynamic disturbances following MI have also been suggested to affect aortic valve (AV) pathology. Therefore, we have ...

 Open Access DOI:10.23937/2378-3516/1410135

Pulmonary Arteriovenous Malformations of Late Revelation

Adil ZEGMOUT, Abdelhalim BOUCAID, Youness AMCHICH, Yassir BENBABA, Hicham SOUHI, Hanane EL OUAZZANI, Ismail Abderrahmane RHORFI and Ahmed ABID

Article Type: Case Report | First Published: June 29, 2020

Pulmonary arteriovenous malformations are scarce and hard to diagnose. We report a case of a very late discovery at an advanced age. Recent vascular imaging techniques (Three-dimensional Computed Tomographic Angiography) have largely contributed to their diagnosis. The patient is treated with arterial embolization which is effective and carries a low complication rate in skilled hands. This case illustrates the clinical circumstances of diagnosis, the diagnostic algorithm, and the differential d...

 Open Access DOI:10.23937/2572-3235.1510064

Evaluation of Solid Focal Liver Lesions by Shear Wave Sonoelastography with FNAC Correlation

Ashu Singla, Vishwanath TT, MD, DNB, Sudha Kiran Das, DMRD, MD, Nagaraj Murthy, MD, Vikram Patil, DNB, Anupama C, DNB and Vinay Raj, MD

Article Type: Original Research Article | First Published: July 11, 2020

50 patients who were diagnosed to have solid focal liver lesions on sonography during the period August 2017 to September 2019 at JSS Medical College and Hospital, Mysuru underwent Shear Wave Sonoelastography [SWE], following which patient underwent ultrasound guided FNAC for histological evaluation. Benign vs. malignant hepatic lesions could be differentiated using a cut off value of 25 kPa. The overall sensitivity & specificity of SWE was found to be 66% and 30% respectively as a standalone te...

 Open Access DOI:10.23937/2469-5734/1510109

Exploring the Factors Influencing the Choice of Oral Care Products: A Review on Personalized Approach

Amit Agrawal, MD and Ankita Gupta, MDS

Article Type: Review Article | First Published: June 29, 2020

Oral care products are the products that are used to cleanse the oral cavity, freshen the breath, and maintain good oral hygiene. Since the dental industry is expanding day by day, numerous types of oral care products are available in the market which makes the selection process very difficult. There are different approaches which influence the choice of oral care products. Among them, personalized approach ranks at the top and should be used by the people to identify the best formulation of ora...

 Open Access DOI:10.23937/2378-3672/1410053

Durable and Effectiveness of Immunotherapy in the Treatment of Metastatic Gastroesophageal Junction Cancer

Carlos Gil Moreira Ferreira, MBBS, Gustavo Bittencourt Camilo, Eleusa Nogueira Dias, Bianca Lopes de Oliveira, Carlos Murilo Schanuel, Juliana Abreu de Vasconcellos and Emílio Campos Augusto Pereira de Assis

Article Type: Case Report | First Published: July 09, 2020

Gastroesophageal junction adenocarcinoma (AJEG) is a neoplasm that is globally prevalent with generally bad clinical outcome. It is estimated that there is an annual incidence of new tumors in the order of 572,034 in the US with about 28,000 new cases and 10,960 deaths attributable to the disease. In Brazil, an estimated 11390 new cases, corresponding to 8690 in men and 2077 in women for the year 2020. About half of the people with cancer of the esophagus or the gastroesophageal junction have me...

 Open Access DOI:10.23937/2377-3634/1410126

Clinical Presentation and Factors Associated with Diabetic Ketoacidosis at the Onset of Type-1 Diabetes Mellitus in Children and Adolescent at Muhimbili National Hospital, Tanzania: A Cross Section Study

Honesta Kipasika, Edna Majaliwa, Benjamin Kamala and Lucy Mungai

Article Type: Original Article | First Published: July 04, 2020

The incidence and clinical presentation of Type 1 diabetes mellitus (T1DM) varies markedly among countries with a worldwide trend of affected children under- 5 years of age. The classical triad of polydipsia, polyuria and weight loss is the most common presentation. Similarly, the frequency of Diabetic Ketoacidosis (DKA) at the onset of T1DM is persistently high in Africa affecting more than two thirds of diabetic children....

 Open Access DOI:10.23937/2469-5831/1510027

Application of Hierarchical Polynomial Regression Models to Predict Transmission of COVID-19 at Global Level

Matthew Ekum and Adeyinka Ogunsanya

Article Type: Research Article | First Published: June 27, 2020

COVID-19 is the disease caused by a novel coranavirus, which outbreak started in Wuhan community of China during December, 2019. World Health Organisation (WHO) started reporting cases of COVID-19 on 21st January. In this research, we aimed at forecasting new cases of COVID-19 per day, using data collected from 21st January to 10th June, 2020, spanning 142 days, by fitting polynomial models. Different model selection criteria were used to determine the most appropriate model among assumed models...

 Open Access DOI:10.23937/2469-5696/1410052

Hemopure, HBOC-201, for Life Threatening Anemia in a Jehovah’s Witness

Joseph R Nellis, MD, MBA, Michael J Devinney, MD, PhD, Christopher C Young, MD

Article Type: Case Report | First Published: June 04, 2020

There are over 1 million Jehovah’s Witnesses in the United States and nearly 8.5 million worldwide. Within the medical community, they are most notably known for their refusal of blood transfusions. Prior studies have shown that healthy euvolemic volunteers tolerate hemoglobin of 5 g/dL, although when faced with the stress of surgery their operative mortalities are over 30%. Herein we explore the use of Hemopure, HBOC-201, an investigational blood substitute, for a frail 72-year-old female Jeh...

 Open Access DOI:10.23937/2643-4512/1710047

Strategies and Methods to Improve Compliance in Special Patient Groups and with Specific Health Problems

Jose Luis Turabian

Article Type: Review Article | First Published: July 09, 2020

Adherence to long-term treatments for chronic conditions remains a challenging issue in general medicine. A low proportion of patients follow the recommendations from general practitioners. The attention of all recurrent or chronic health problems and turning points of natural or physiological situations but that present medical health risks requires co-operation with patients and changes in behaviour. Taking into account the complexity of the phenomenon of therapeutic compliance, it is necessar...