Open Access DOI:10.23937/2474-3631/1510041
Pembrolizumab for Locally Advanced or Recurrent/Metastatic Cutaneous Squamous Cell Carcinoma: Long-Term Results of the Phase 2 Keynote-629 Study
Munoz-Couselo E, Hughes BGM, Mortier L, Grob JJ, Gutzmer R, Roshdy O, González Mendoza R, Schachter J, Arance A, Grange F, Meyer N, Joshi A, Billan S, Ojavee SE, Yuan J, Gumuscu B and Bratland Å
Article Type: Poster | First Published: 2024/07/15
Median time from first dose to the data cutoff date of September 13, 2023, was 52.4 months (range, 47.6-56.9) for the LA cohort, 64.7 months (range, 62.1-69.5) for the R/M cohort, and 63.1 months (range, 47.6-69.5) in the total population (Figure 2, Figure 3, Figure 4, Figure 5, Table 1, Table 2 and Table 3)....
Open Access DOI:10.23937/2643-4016/1710039
Deep Wound Infection after Internal Fixation by Ankle Fracture Treated with Calcium Sulfate Beads Carrying Antibiotics: Case Report
Cesar David Hernández-Lira, Diego Rafael Gonzalez-Ramos, Mario José Lezama-Peniche and Víctor Manuel Alayon-Vazquez
Article Type: Case Report | First Published: 2024/07/15
It has been shown in the literature that ankle fractures account for about 10% to 15% of all fractures, and that about 20% of all ankle fractures will require an internal fixation determined directly by a syndesmosis injury. Reported complications range from 1% to 36.5%, including short-term soft tissue infections. It has also been shown that the application of calcium sulfate beads added with antibiotics as a local method in the bone reduces the risk of infection and biofilm formation in this i...
Open Access DOI:10.23937/2572-3286/1510097
Penile Calciphylaxis: Misdiagnosis of a Fatal Condition
Rajashree Thirumeni, DO and Michael Carson, MD
Article Type: Case Report | First Published: 2024/07/14
Penile calciphylaxis is a rare complication most often occurring in patients with end-stage-renal-disease on dialysis. The condition is associated with a high mortality rate. Misdiagnosis of this life-threatening condition is common. We describe a case of a 41-year-old male with end-stage-renal disease on hemodialysis who suffered multiple admissions for a penile wound. He was misdiagnosed repeatedly leading to significant morbidity. The patient elected hospice care. This case report is intended...
Open Access DOI:10.23937/2572-4061.1510059
SPE-HPLC-UV Analysis of Phthalates in Biological Fluids of Transfused Mothers in Sacred-Heart Hospital Lantoro Abeokuta Nigeria
Olumayowa Joshua Onipede, Gregory Olufemi Adewuyi, Adejumoke Idowu Ayede, Oladapo Olayemi, Folasade Adenike Bello, Jonathan O. Osamor and Gregory Olawole Arifalo
Article Type: Research Article | First Published: 2024/07/12
Exposure to phthalates through blood transfusion has been a concern of research, as studies have been inconclusive on their leaching of phthalates to the blood of the transfused patient. This study examined levels of diethyl phthalate (DEP), dipropyl phthalate (DPP), dibutyl phthalate (DBP), diethylhexyl phthalate (DEHP) and monobutyl phthalate (MBP) in blood serum, urine and breast milk samples of transfused mothers in Sacred Heart Hospital Lantoro Abeokuta Southwest Nigeria. Samples were extra...
Open Access DOI:10.23937/2643-4016/1710038
Digital Neurolipoma: A Case Report
Hamza Madani, Ahmed EL Ghazzal, Hicham Ait Benali and Mohammed Shimi
Article Type: Case Report | First Published: 2024/07/12
Lipomas of the finger are extremely uncommon, slow-growing benign tumors composed of fibrous adipose tissue, accounting for less than 5% of benign hand tumors. Neurolipoma, fibrolipoma or lipofiromatous Hamartoma is a lipomatous tumoral process involving peripheral nerves and their dividing branches, particularly in the hands and feet....
Open Access DOI:10.23937/2378-3656/1410453
Mesenteric Cyst Manifested as Partial Intestinal Obstruction
Said Abdulrahman Salim Mzee, Mohammed M.M Ali, Cosmos Mutisya, Zakari Shaibu, MD, PhD, Arnold Kiptoo Mutai, Swalah Suleiman Salim Al-Busaidy and Isah Adamu Danbala, MD, PhD
Article Type: Case Report | First Published: 2024/06/30
Mesenteric cysts are rare abdominal masses that can present with varied clinical manifestations, including partial intestinal obstruction. We present a case of a 17-year-old boy with no significant medical history who exhibited chronic abdominal pain, fluctuant abdominal swelling, constipation, loss of appetite, and bilious projectile vomiting. Previous history of blunt trauma to the hypogastric region at age 10 was noted. Laboratory investigations showed elevated white blood cell count, neutrop...
Open Access DOI:10.23937/2474-3658/1510324
The Role of Microbiome in Malaria Transmission and Severity
Kwame Kumi Asare and Paul Ekow Duntu
Article Type: Review Article | First Published: 2024/07/10
Malaria is a public health concern, especially in Sub-Saharan Africa. Several malaria control programs to treat, control, and eradicate malaria have been implemented, however, more than 90% of malaria-related deaths in under five years occur in Africa. With the emergence and spread of artemisinin-resistant P. falciparum, global malaria control now focuses on vaccine development and a search for novel and efficient antimalarial drugs. Although current evidence shows host microbiota play a signifi...