Open Access DOI:10.23937/2572-4061.1510040

Evaluation of Effect of Ethanol Extraction of Graptophyllum pictum on Zebrafish (Danio rerio) Embryo Model through Toxicity Assay Assessment

Azrina Zainal Abidin, Subashini Visepomaran, Santhra Segaran Balan and Hasnah Bahari

Article Type: Original Article | First Published: September 17, 2021

Graptophyllum pictum is a medicinal plant that helps to cure different forms of disease due to the availability of beneficial phytochemicals such as flavonoids, steroids, alkaloids, saponins and glycosides. The purpose of this research was to evaluate the toxicity effect of G. pictum extract on zebrafish embryos (Danio rerio) at different concentrations. G. pictum was extracted using the ethanol method. A toxicity test was done by exposing the Danio rerio embryo to the G. pictum extraction at di...

 Open Access DOI:10.23937/2469-5750/1510105

Pyoderma Gangrenosum is Associated with Low Socioeconomic Status: A Single-Site, Cross-Sectional Study

Anna Maria Vromans, MS, Josiah Williams, BS, Arjun M Bashyam, MD, William W Huang, MD, MPH, Steven R Feldman, MD, PhD and Lindsay C Strowd, MD

Article Type: Retrospective Study | First Published: September 08, 2021

Pyoderma gangrenosum (PG) is an uncommon, non-infectious, inflammatory skin disorder affecting individuals of all ages. Research characterizing socioeconomic status (SES) of this patient population is limited. Understanding the SES of a patient population is vital to providing a personalized approach for disease management that addresses potential barriers including transportation, work flexibility, cost of medications, and wound care. A single-institution retrospective study of 255 adults with ...

 Open Access DOI:10.23937/2474-1353/1510124

Women’s Health Insurance Status in Senegal West Africa

Rhonda BeLue, Jeremy Green, Adaobi Anakwe and Mor Diaw4

Article Type: Original Research | First Published: September 17, 2021

Senegalese women of childbearing age continue to be disproportionately affected by communicable and noncommunicable disease, yet still face reduced health care access despite the expanding coverage of universal health insurance schemes. There is need to understand the role of women’s socio-demographic positioning and household decision-making autonomy on their health care insurance participation. We analyzed data of a representative sample from the 2016 Senegalese Demographic and Health Survey...

 Open Access DOI:10.23937/2469-5718/1510200

Feasibility of a Six Week High Intensity Interval Training Program in Patients with Non- Small Cell Lung Cancer: A Randomized Pilot Study

Emily Walsh, Guy Hajj-Boutros, Guillaume Bastarache, Andréa Faust and Alain-Steve Comtois

Article Type: Research Article | First Published: September 22, 2021

High Intensity Interval Training (HIIT) has become a mainstream, frequently investigated form of exercise training and has been used as a modality for physical activity in cancer patients. The objective of this study was to determine the feasibility of advanced Non-Small Cell Lung Cancer (NSCLC) patients performing a program of HIIT. To our knowledge, this is the first study to investigate a HIIT program for these patients. Ten participants were recruited for this study. Five were controls and f...

 Open Access DOI:10.23937/2643-4571/1710037

Successful ICU Care in a MERRF Patient with Severe Covid-19

Scott Clanton II, Rajani Adiga, MS, Amy Christie, MD, FACS and Dennis Ashley, MD, FACS, FCCM

Article Type: Case Report | First Published: September 13, 2021

Mitochondrial myopathies are a spectrum of rare diseases caused by a genetic defect in ATP production at the level of the electron transport chain. The degree of disability is variable, but often patients are severely ill and highly susceptible to increased morbidity and mortality with infection. Covid-19 is known to be especially virulent in patients with significant comorbidities. In this case, a 27-year-old man with Myoclonus Epilepsy with Ragged Red Fibers (MERRF) presented in severe shock d...

 Open Access DOI:10.23937/2643-4571/1710036

Reducing Global Health Inequalities in People with Prader- Willi Syndrome: The Role of the International Prader-Willi Syndrome Organization

Anthony Holland and Marguerite Hughes

Article Type: Opinion Piece | First Published: September 10, 2021

The International Prader-Willi Syndrome Organization (IPWSO) is a global charity first established in 1991 to support the needs of children and adults with the genetically determined neurodevelopmental disorder, Prader-Willi Syndrome (PWS), together with their families and health and social care professionals working with them. PWS affects all races and both genders equally and is associated with a complex physical and behavioral phenotype that requires interdisciplinary lifelong health support,...

 Open Access DOI:10.23937/2469-5769/1510079

Assessment of Magnitude and Associated Factors of Immunization Drop Out Rate for Children Aged 12-23 Months In Abobo District South West Ethiopia

Ayalew Kassaw, BSC, MPH IN RH, Abebe Gebere Mariam, BSC, MPH, PHD, Alemi Kebede, BSC, MPH IN RH, and Fassikaw Kebede, BSC, MPH (Epidemiology)

Article Type: Research Article | First Published: September 20, 2021

Vaccination is the epicenters of preventive care for good children health outcomes in each nation. Nevertheless, numbers of factors have been hindering the attainment of targets to provide complete vaccination in different nations. The aim of this study is to assessed predictors of immunizations in 12-23 months aged children in Abobo District, Gambela regions south west Ethiopia. A community based cross-sectional study was employed in 436 pairs of mothers to children aged 12-23 months from 12 ma...

 Open Access DOI:10.23937/2643-4563/1710031

Incidentally Found Thyroid Metastases in Head and Neck Squamous Cell Carcinoma - How to Manage It?

Gama R, Oliveira P, Teixeira M, Castro F and Condé A

Article Type: Original Article | First Published: September 10, 2021

The authors aim to review the available literature regarding incidentally found thyroid carcinoma during lymph node dissection for primary head and neck squamous cell carcinoma (SCC), in order to potentially support clinical decision about management of this unexpected entity. 2 clinical cases are described and a systematic review of the relevant literature on the subject is performed based on Pubmed® database. We reviewed a total of 102 cases. The primary SCCs sites were larynx, oral cavity, a...

 Open Access DOI:10.23937/2377-3634/1410149

Treating Diabetic Peripheral Neuropathy Using a Novel, Nanotechnology-Based Topical Formulation to Improve Pain, Sensitivity, and Function

Jeffery LaMour, DPM, Douglas Grimm, DPM, Ester Smith, PhD, Zvi Yaniv, PhD and Peter Hurwitz

Article Type: Original Research | First Published: September 24, 2021

Diabetes has become one of the largest global healthcare problems of the 21st century. More than 100 million U.S. adults are now living with diabetes or pre-diabetes. The Centers for Disease Control and Prevention (CDC) reports that as of 2015, 30.3 million Americans (9.4% of the U.S. population) have diabetes and 1.5 million Americans are diagnosed with diabetes every year. The population prevalence of diabetes in the US is approaching 10% and is increasing by 5% each year. Annual costs for dia...

 Open Access DOI:10.23937/2377-3634/1410148

Prevalence, Contributing Factors and Management Strategies (Self-Management Education) of Type 2 Diabetes Patients in Nigeria: A Review

Emos E Tella, Ismaeel Yunusa, Judith H Hassan, Ibrahim A Chindo and Victor B Oti

Article Type: Review Article | First Published: September 17, 2021

Diabetes is one of the major causes of morbidity and premature mortality globally with over 371 million people worldwide and more than 80% of morbidity and mortality due to diabetes occurred in the low- and middle-income countries (LMICs) including Nigeria, which has the highest burden of diabetes in Africa. The high number of medical admissions and deaths (15% and 22%) due to diabetes complications in Nigeria reflect the poor quality of care. Therefore, this review aims to discuss the prevalenc...