Open Access DOI:10.23937/2378-3656/1410365
Preventing Progression of Chronic Kidney Disease with Plant-Based Diet
Gunadhar Panigrahi, MD, FACC, FACP, DipABLM
Article Type: Case Report | First Published: September 29, 2021
A 72-year-old female has long standing history of coronary artery disease (CAD), hypertension, hyperlipidemia, and obesity. In 1987, at the age of 39 years, she had sustained an anterior wall myocardial infarction. She had cardiac catheterization and received a stent to the left anterior descending coronary artery (LAD), the infarct related artery. In 2007, she had sustained a second heart attack at the age of 59 years, and this time she was treated with simple balloon angioplasty to the LAD. In...
Open Access DOI:10.23937/2474-3682/1510190
COVID-19 Associated Cerebral Mucormycosis
Abhishek Singh, Kapildev Soni, Satish Kumar Verma and Anjan Trikha
Article Type: Clinical Image | First Published: October 30, 2021
A 33-year-old female was admitted to COVID ICU after testing positive for the disease with 7 days history of fever, cough, inability to open as well as pain in the left eye, and inability to speak with right sided hemiparesis. She was known diabetic and hypertensive. Clinical examination showed presence of multiple pus points in left infratemopral region. Its microscopic examination showed wide area of necrosis along with cluster of mucormycosis. Due to sudden deterioration of patients GCS, CECT...
Open Access DOI:10.23937/2643-4474/1710087
Case of Endoscopic Surgical Treatment of Thoracic Arachnoid Cyst
Roman Khalepa and Yuliy Kubetskiy
Article Type: Case Presentation | First Published: October 23, 2021
Spinal arachnoid cysts are the benign intradural extramedullary lesions that usually occur at the thoracic region. Such cysts can cause compression of spinal cord with symptoms of myelopathy. The diagnosis is clinical and radiological with the use of MRI. Nowadays there are some surgical options to eliminate compression of spinal cord: laminectomy and total removal of the arachnoid cyst, puncture aspiration, cyst fenestration, cystoperitoneal shunting. Each of these options can be used in arachn...
Open Access DOI:10.23937/2572-4053.1510036
The Importance of Proximal RCA Stenosis is Associated with Severe OSAS Patients
Tolga Dogan, PhD, Baris Sensoy, PhD and Aygul Gunes, PhD
Article Type: Original Article | First Published: October 25, 2021
The aim of this study was to evaluate the relationship of regional selectivity in coronary arteries with OSAS severity using the Syntax (SX) score in OSAS (Obstructive sleep apnea syndrome) patients. This retrospective study included 68 OSAS patients with coronary artery disease (CAD) who were followed up at Cardiology and Neurology Outpatient Clinic in our hospital between January 2019 and October 2020. Patients with previously diagnosed OSAS were separated into 2 groups as mild-moderate OSAS g...
Open Access DOI:10.23937/2572-4193.1510110
Validation Study: Evaluating Phenotypic Expression of Bitter Taste Receptors
Mohamed A Taha, MD, Colin J Shortess, BS, Mackenzie J Noonan, BS, C Chambliss Harrod, MD, Mary JR Barham, Rowda R Mousa, PE and Henry P Barham, MD
Article Type: Research Article | First Published: October 25, 2021
Bitter taste receptors (T2Rs) have shown to play a role in sinonasal innate immunity against SARS-CoV-2. A taste strip test kit has been used in prior COVID-19 studies (prototype version), and has shown significant results. This study addresses the validity of this test kit for assessing the genotype/phenotype correlation of T2R expression, with emphasis on the importance of performing phenotypic testing, rather than genotype testing, as a measure for T2R function as a part of innate immunity ag...
Open Access DOI:10.23937/2474-3658/1510230
An Accuracy-Based Approach to the Microbiologic Diagnosis of Pulmonary Infection
John Ferguson, MD, MPH, Cyprien Jungels, DO and Michael Gailey, DO
Article Type: Review Article | First Published: October 22, 2021
Over six million cases of pneumonia are diagnosed annually in the United States. Clinicians commonly experience uncertainty regarding the accuracy of laboratory tests as these values are not well-published or easily accessible. Performance data of diagnostic tests are needed to assist clinicians in procuring a microbiologic diagnosis. We undertook a literature search to assess the accuracy of diagnostic tests for pneumonia, identified through a search of MEDLINE-indexed journals. Sensitivity and...
Open Access DOI:10.23937/2469-5858/1510126
Meta-Analysis of Acute Sarcopenia among Hospitalized Elderly Patients
Arthur George Gonzales, MD and Miguel Ramos, MD
Article Type: Meta Analysis | First Published: October 22, 2021
The electronic bibliographic databases used are MEDLINE via PUBMED and The Cochrane Library (Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Methodology Register). The search strategy included a combination of appropriate MeSH and other free-text terms including the following key words: “sarcopenia”, “acute care”, “hospitalisation”, and “elderly”. There was no language restriction for the searches. Abstracts and subseque...
Open Access DOI:10.23937/2469-5750/1510108
Dermoscopic Findings of Pilotropic Mycosis Fungoid: A Rare Variant
Benahmed Jihane, Znati, Meziane, Ismaili, Benzekri and Senouci
Article Type: Case Report | First Published: October 23, 2021
Pilotropic mycosis fungoid (PMF) is a rare variant of mycosis fungoides (MF) with distinctive clinicopathological features, accounting for 1 to 5%. It is characterized by a broad spectrum of clinical features and has a more aggressive clinical course than conventional MF. At the onset of its progression, pilotropic mycosis fongoides is sometimes difficult to distinguish from classical mycosis fongoides with follicular involvement. PMF diagnosis is challenging and can mimick other conditions. Der...
Open Access DOI:10.23937/2469-5807/1510120
A Review of the Sub-Classification of Lymph Node Biopsies Reported as Reactive Lymphadenitis at Kenyatta National Hospital, Kenya
Chepkorir Cynthia Chemonges, Nyagol Joshua, Massimo Granai, Stefano Lazzi, Joseph Rugumu Ndungu and Lorenzo Leoncini
Article Type: Original Research | First Published: October 25, 2021
Lymphadenopathy is common in both adult and paediatric patients in Kenya. It has a broad differential diagnosis, the most common being non-specific reactive lymphoid hyperplasia. Prevalence and morbidity of malignancies in early stages, such as micro lymphoma in reactive lymphadenitis remains poorly investigated. This study evaluated the histopathologic patterns of lymph node biopsies reported as reactive lymphadenitis at Kenyatta National Hospital between 2013-2019. Formalin fixed paraffin embe...