Open Access DOI:10.23937/2469-5696/1410073
Aplastic Anemia-Related Mortality in Brazil, 2000-2018
Augusto Hasiak Santo
Article Type: Case Report | First Published: January 14, 2022
Aplastic anemia (AA) is a rare and serious disease, potentially life-threatening, that affects hematopoietic stem and progenitor cells and is characterized by pancytopenia and a hypoplastic bone marrow. The development of AA result from the destruction of hematopoietic cells by three main mechanisms, including direct environmental injury, dysregulated immune system, and primary inherited or acquired bone marrow failure syndrome. There are no AA specific markers then the diagnosis is reached by e...
Open Access DOI:10.23937/2469-5866/1410041
Magnetic Particles in the Human Body: A Short Review on the Effects of these Particles on the Human Health
Manfred Fähnle
Article Type: Review Article | First Published: January 08, 2022
Magnetic particles in the human body have various effects on the human health, ranging from positive effects in the treatment of diseases, e.g., by a hyperthermia treatment, to negative effects, e.g., on Alzheimer’s disease. In the present manuscript a short review is given on these effects of magnetic particles in the human body. It is written that by exposing diseased tissue to elevated temperature for a period of time, called hyperthermia, is a promising treatment of human diseases. Cells a...
Open Access DOI:10.23937/2643-4466/1710036
Association between the Third Trimester Vaginal Microbiome and Time from Full Cervical Dilation to Delivery: An Exploratory Study
Steven S Witkin, Daniel Skupski, Antonio F Moron, Allison Boester, Iara M Linhares and Larry J Forney
Article Type: Research Article | First Published: December 31, 2021
Bacteria from the vagina are transported into the uterus during labor. We evaluated if the vaginal microbiome in the third trimester of pregnancy was related to the length of the second stage of labor. The composition of the vaginal microbiome in 73 women in their third trimester was measured by analysis of the V1-V3 region of the gene coding for bacterial 16S ribosomal RNA. The vaginal concentration of D- and L-lactic acid was determined by ELISA. The time from full dilation to delivery was ob...
Open Access DOI:10.23937/2643-3966/1710049
Coronary Microvascular Injury in the COVID-19 Patient: The Need for Imaging Studies in Post-COVID-19 Cardiovascular Syndrome
Paula Marcela Cuéllar-Pinzón, MD, María Paula Montes-Lozano, MD, Marco Antonio Suárez- Fuentes, MD, Miller Jesús Melo-Mora, MD and Michael Gregorio Ortega-Sierra, MD
Article Type: Editorial | First Published: January 08, 2022
The COVID-19 pandemic has generated numerous questions about the pathophysiology of the acute phase of this disease, and as time goes by, also of the chronic phase, known as post-COVID-19 syndrome. Although the neurological phenotype (post-COVID 19 neurological syndrome) is the most debated, the evidence points to the fact that the main manifestations of post-COVID 19 patients, regardless of disease severity, are dyspnea, fatigue, tachycardia, and difficulties in performing activities of daily l...
Open Access DOI:10.23937/2474-3658/1510242
Efficacy and Safety Assessment of Three Artemisinin- Based Combination Therapy (Acts) in the Treatment of P. falciparum Malaria in Cameroon
Theresia Njuabe Metoh, Roger Somo-Moyou, Philip Gah Fon, Ernest Tambo, Jun-Hu Chen and Zhou Xiao-Nong
Article Type: Research Article | First Published: December 31, 2021
Artemisinin-based Combination Therapies (ACTs), have been reported to be effective against multidrugresistant Plasmodium falciparum. There are controversies in the choice of the type of ACTs to be used at hospitals settings and health centers. This is mostly determined by the cost and less side effects reported for each drug leading to an over prescription and consumption of some ACTs compared to others and consequently to drug resistance. This situation highlight the importance for constant mon...
Open Access DOI:10.23937/2469-5793/1510143
Increasing HIV Knowledge among Community Workers: Optimizing the Continuum of Care in Davao, Philippines
Danielle A. Walker, PhD, MA, CHES, Charlyn T. Gambe, RSW, MSSW, Carol J. Ustach, BA, Kristianna Altamirano, MS, Sarah J. Templeton, DNP, FNP-C, Mackenna Mason, BS, Abigail Cruzen, RN and Yujin Lee, RN
Article Type: Research Article | First Published: December 23, 2021
Over 38 million individuals have been diagnosed with Human Immunodeficiency Virus (HIV) worldwide, and the Southeast Asia and Pacific region accounts for 5.8 million of those. Regional progress reduced transmission by 9%, but the Philippines' rising epidemic is largely overshadowed by other countries experiencing tremendous improvement. The Philippines has seen a 203% increase in new infections from 2010-2020, while studies suggest only 2.3% of the population has been tested. Before testing prog...
Open Access DOI:10.23937/2474-1353/1510133
Prevalence of High Risk Pregnant Women Who Attend Antenatal Care and Associated Factors in Jimma Medical Center, Jimma Town, South Western Ethiopia
Jemila Nesro, Midhagsa Dhinsa and Melkamu Gelan
Article Type: Research Article | First Published: December 31, 2021
Around 303,000 women and adolescent girls pass on from pregnancy and childbirth-related complications in 2015 and 99% of these deaths occur in developing countries. That same year, 2.6 million babies were stillborn. Almost all of the maternal deaths (99%), child deaths (98%), Sixty percent of the stillbirths (1.46 million) occurred during the antepartum period and mainly due to untreated maternal infection, hypertension, and poor fetal growth and occurred in low- and middle-income countries. The...