Open Access DOI:10.23937/2572-3987.1510032
Paxlovid's Double-Edged Sword: Treating COVID-19 and the Risk of Viral Load Rebound
Sarah Hughes, PharmD, Jessica Russo, PharmD, MBA and Kimberly Finley, PharmD, BCACP
Article Type: Review Article | First Published: 2024/11/29
Coronavirus disease 19 (COVID-19) is an infectious respiratory illness caused by SARS-CoV-2 virus that has caused more than 3 million deaths since its emergence as a public health emergency in January 2020 [1]. Through emergency efforts, pharmaceutical companies such as Pfizer, Moderna, and Johnson and Johnson were able to create vaccinations to reduce hospitalizations and death related to COVID-19. Until 2021, social distancing combined with N-95 masks and the primary series of vaccination were...
Open Access DOI:10.23937/2572-3235.1510131
Diagnostic Efficacy of Dynamic Maneuver in Contrast Enhanced Computed Tomography Compared to Conventional Contrast Enhanced Computed Tomography in the Imaging of Neck Region
Rubi P, MSc, Dinesh Sekar, MSc and Ramiya R, MSc
Article Type: Original Research | First Published: 2024/11/24
Neck lesions encompass a variety of pathological conditions, including carcinomas, lymphadenopathy, and abscess and thyroid nodules. The advancements of Computed Tomography (CT) play major role in detecting neck pathologies. Injection of contrast media is primary while imaging neck region, So Contrast Enhanced Computed Tomography (CECT) is the best choice for this imaging. Though, CECT performed with dynamic maneuvers plays important role in assessing the lesion size, margins and relationship wi...
Open Access DOI:10.23937/2643-4563/1710058
Prostate Cancer Tissue Biomarkers Associated with Tumor Microenvironment and Progression: Application of NMR Spectroscopy
Pradeep Kumar and Sujeet Kumar Mewar
Article Type: Review Article | First Published: 2024/11/24
In cancers of men, prostate cancer (PCa) is a prevalent malignancy. Finding biomarkers is important and useful for figuring out PCa incidence and prognosis. For males over 50, prostate cancer (PCa) is the most prevalent adenocarcinoma type of cancer diagnosis. PCa typically has a variety of clinical and pathological symptoms and is heterogeneous and multifocal. There is currently little knowledge about the molecular genetics of the progression mechanism behind this variability. The most effectiv...
Open Access DOI:10.23937/2377-3634/1410185
Knowledge, Attitude and Sociocultural Correlates to Diabetes and Hypertension among Adults Living in Enugu-South L.G.A of Enugu State
Uchechukwu I. Ezue, King-David I. Ahuchaogu, Chidinma A. Omeke, Maureen A. Nwokorie, Ifeanyi I.Ofonere, Christabel U. Ogwezi and Chidinma J. Nnamani
Article Type: Original Research | First Published: 2024/11/25
Non-communicable diseases are traced to be the leading cause of both mortality and morbidity worldwide and there are indications the numbers will continue to rise. Diabetes and Hypertension are both Non-communicable diseases. Hypertension is a condition in which the force of the blood against the arterial walls is too high. Diabetes is a group of diseases that results in too much sugar in the blood. It is a chronic, metabolic disease characterized by elevated levels of blood glucose in the body....
Open Access DOI:10.23937/2469-5793/1510163
Prevalence of Traditional Medicine Practices amongst Mothers of under-Five Children at the Federal University Teaching Hospital Owerri, Imo State, South-East Nigeria
Anthony Okeoghene Eguvbe, Nkencho Osegi, John Esiso Egbagba and Kellybest Ibasimama Davids
Article Type: Original Research | First Published: 2024/11/23
Traditional medicine is sometimes known as alternative medicine. It is an indigenous medical system based on the beliefs about the causes of illness as well as the customs and culture of the people. According to the World Health Organization (WHO), traditional medicine is "the knowledge, skills and practices based on the theories, beliefs and experiences indigenous to different cultures, used in the prevention, diagnosis, improvement or treatment of physical and mental illness." There are a lot ...
Open Access DOI:10.23937/2378-3419/1410192
Blood Plasma Metabolomic and Lipidomic Signatures of Prostate Cancer Using NMR Spectroscopy
Pradeep Kumar, Virendra Kumar, Rajeev Kumar, Sanjay Sharma, Sanjay Thulkar and M A Khan
Article Type: Research Article | First Published: 2024/11/25
Prostate cancer (PCa) with metastasis remains an incurable disease requiring early diagnosis and effective treatments. Bone metastasis is the predominant cause of mortality from PCa. Aggressive PCa metastasizes or spreads to bones, such as the hip, spine, and pelvis. Bone metastatic PCa is considered an advanced stage. This study was designed to determine the association of these metabolites/lipids with the progression of metastases cascade in PCa. Thus, the present study is based on 1H-NMR to i...
Open Access DOI:10.23937/2469-5718/1510269
Role of Exercise in Prevention and Treatment of Osteoporosis - A Narrative Review
Merry Mathew, Mimi Zumwalt and Sachi Khemka
Article Type: Review Article | First Published: 2024/11/22
Osteoporosis is characterized by diminished bone density and structural integrity, which presents a significant health concern, particularly among older adults and postmenopausal women. Exercise has emerged as an important preventive measure and therapeutic intervention for osteoporosis, with positive impacts on bone metabolism and bone mineral density (BMD). This narrative review examines the utility of exercise for the management of osteoporosis in postmenopausal women, with a special focus on...