Open Access DOI:10.23937/2572-4061.1510044

Meta-Analyses of Glyphosate and Non-Hodgkin’s Lymphoma: Expert Panel Conclusions and Recommendations

Kirman CR, Cocco P, Eslick GD, Villeneuve PJ and Hays SM

Article Type: Review Article | First Published: March 31, 2022

An expert panel was assembled to support a review of a series of recent publications using a modified Delphi format. These publications were scored based on a consideration of confidence in their methods, results, conclusions, and applicability to risk-based decision making. Mean confidence scores for the papers reviewed ranged from 53 to 74 (maximum score = 100), and key strengths and concerns were identified. This review highlights the need for transparency in meta-analyses. Different conclusi...

 Open Access DOI:10.23937/2572-4061.1510043

Cytotoxic Effects of Ceteareth-20 and Paraffinium Liquidum In Vitro

Duygu Kirkik, PhD, Fatih Hacimustafaoglu, PhD and Derya Altunkanat, PhD

Article Type: Research Article | First Published: March 31, 2022

The aim of this study is to investigate the effects of ceteareth-20 and paraffinium liquidium on cell viability and cytotoxicity in human lymphocyte in vitro. We studied the cytotoxic and inhibitory effects of ceteareth-20 and paraffinium liquidum on cell proliferation using lactate dehydrogenase (LDH) assay and cell proliferation (WST-1) assay. The cytotoxicity was enhanced when cells were treated with 1%, 5%, 25% and 50% paraffinium liquidium dilutions (p < 0.05). Moreover, cell number signifi...

 Open Access DOI:10.23937/2572-4193.1510118

Management of Oral Cavity Mucormycosis in a Ketoacidotic Patient with Targeted Debridement and a Palate Obturator

Jennifer Adams, BS and Adam Bender-Heine, MD

Article Type: Case Report | First Published: March 31, 2022

Mucormycosis is an opportunistic mycosis common in poorly-controlled insulin dependent diabetic patients particularly with ketoacidosis. It often begins as a nasal and paranasal sinus infection with inhalation of spores into the paranasal sinuses of a susceptible host. In this case report we review the clinical symptoms, relevant imaging, and management of a diabetic patient with mucormycosis threatening his better seeing eye. This case report offers the clinician a review of important clinical ...

 Open Access DOI:10.23937/2572-3243.1510110

Does Open Reduction and Internal Fixation for Proximal Humeral Fractures Increase the Incidence of Osteonecrosis of the Humeral Head? A Meta-Analysis of Randomized Controlled Trials

Wei Li, Lei Chen, Dongqiang Gu and Shunxin Zhang

Article Type: Research Article | First Published: March 31, 2022

Open reduction and internal fixation (ORIF) for proximal humeral fractures is said to increase the incidence of osteonecrosis of humeral head. Fact or fiction? Therefore a systematic review was performed, searching multiple databases, online registers of randomized controlled trials (RCTs), and the proceedings of major meetings. All RCTs comparing the incidence of osteonecrosis of humeral head between ORIF and conservative treatment were identified. Two authors independently assessed methodologi...

 Open Access DOI:10.23937/2474-3658/1510254

Socio-Economic Factors and ITN Policies in Senegal, a Country Close to Malaria Elimination

Elvire Mfueni Bikundi, Annie Robert, Catherine Bouland, Edouard Akotionga, Ndèye Mareme Sougou and Yves Coppieters

Article Type: Original Article | First Published: March 31, 2022

Malaria is a global public health problem with many cases each year in the world (241 million cases with 247,000 deaths (67% were under five children) in 2020. Most malaria cases occur in Sub-Saharan African countries (93%). The objective of our study was to observe how is implemented ITN policies against malaria with a view on socio-economic factors, in Senegal, which is country close to malaria elimination. Data used for analysis is from Demographics and Health Surveys 2019 for Senegal. Linear...

 Open Access DOI:10.23937/2474-3690/1510067

Caffeine Elevates Blood Pressure

Maria Teresa Ambrosini, BS, PharmD, BCPS

Article Type: Commentary | First Published: March 31, 2022

Caffeine is known to increase blood pressure, and it is recommended that there be a 30 minute waiting period between drinking caffeinated beverages, eating a meal, or exercise before taking a blood pressure reading. Daily consumption of coffee, either regular or espresso, or other caffeinated beverages before a reading results in elevated blood pressure. Caffeine is widely distributed throughout the body and it is water and fat soluble. It has an elimination half life of 5 hours, which is longer...

 Open Access DOI:10.23937/2469-5858/1510128

The Experiences of Older Adults Labeled as a High Fall Risk: A Generic Qualitative Inquiry

Stacey Morningwake, PhD

Article Type: Original Article | First Published: March 30, 2022

Falling is a multifaceted phenomenon that greatly impacts older adults. Throughout fall research, the aspect of fall risk labeling has been unobserved. This study aimed to explore the perceptions of older adults given high fall risk labels. The focus of the study surrounded the research question, “What is the experience of older adults who have been labeled as a high fall risk?” Eight older adults aged 65-85 participated in this generic qualitative inquiry, with each participant given a high...

 Open Access DOI:10.23937/2469-584X/1510084

CD 90 as Cancer Stem Cell Biomarker in Liver Cancer

Mohamed Hussein

Article Type: Research Paper | First Published: March 25, 2022

Liver cancer is the end-stage of chronic liver diseases. The main aetiologies of chronic liver diseases CLDs are chronic hepatitis C virus (HCV) infection. The aim of this work was to evaluate diagnostic value of CD-90 in patients with chronic liver disease (CLD) Fibrosis, Liver cancer and healthy individuals. The present study included Fibrotic patients, Liver cancer patients, in addition individuals were enrolled in this study as control group. AFP and CEA were estimated in all groups. CD-90 w...

 Open Access DOI:10.23937/2474-1353/1510137

Application of Reproductive Related Gene Detection in Etiological Analysis of Recurrent Non-Transplantable Embryo

Yingjie Zhou, Peng Liu, Yue Geng and Li Zhang

Article Type: Original Research | First Published: March 24, 2022

Gamete maturation and embryonic development are directly related to genetic factors. If the patient has genetic abnormalities, the efficacy of clinical treatment may be seriously affected or even ineffective. In this study, we analyzed the variation of reproductive related gene associated with the adverse outcome of assisted reproductive therapy, recurrent non transferable embryo, and discussed the key points of genetic counseling and the selection of clinical treatment schemes for recurrent non...

 Open Access DOI:10.23937/2469-5718/1510218

Impact of Resistance Training on Sports Performance and Muscular Adaptations

Zachary M. Townsend

Article Type: Review Article | First Published: March 31, 2022

Resistance training helps contribute to sportsperformance and general health benefits. In particular, resistance training is linked to physiological adaptations causing increases in muscular strength, endurance, power, and hypertrophy. These muscular adaptations can be translated to improvements in sports performance. With this concept in mind, sports performance coaches can manipulate training variables in order to optimize athletic performance and help athletes achieve their goals. However, ad...