Open Access DOI:10.23937/2378-3656/1410389

Prolonged Recovery of Neuromuscular Transmission during General Anaesthesia after Mivacurium Administration - Case Report

Paweł Radkowski, PhD, Katarzyna Podhorodecka and Mariusz Kęska

Article Type: Case Report | First Published: April 29, 2022

Mivacurium is the shortest-acting nondepolarizing relaxant, used for brief procedures, such as those performed in the ambulatory setting. The recommended intubating dose of 0.2 mg/kg usually provides a clinically effective neuromuscular block for approximately 15 to 20 minutes and spontaneous recovery is 95% complete within about 25 to 30 minutes. 71-years-old woman was admitted for an elective laparotomy surgery with an intraoperative examination. Standard monitoring and TOF Scan (both the addu...

 Open Access DOI:10.23937/2474-3682/1510202

Transcranial Color-Coded Duplex Ultrasonography in the Diagnosis of Brain Aneurysm

Issac Cheong, MD

Article Type: Clinical Image | First Published: April 28, 2022

A 50-year-old male with no relevant clinical history presented sudden headache accompanied by nausea, which evolved with facial paresis and drowsiness with a computed tomography (CT) showing bilateral subarachnoid bleeding, being admitted to the intensive care unit. We performed a transcranial color-coded duplex ultrasonography (TCCS) that showed the presence of a rounded image at M2 portion of the right middle cerebral artery (rMCA) that measured 20 mm × 21 mm with a positive color Doppler sig...

 Open Access DOI:10.23937/2469-5777/1510098

Acute Lower Extremity Posterior Compartment Syndrome: A Rare Complication of Apixaban Use

Jennifer Adams, BS, Jose H Ramos, MD, Shyama Appareddy, MD and Gustavo Garcia, MD, FACP

Article Type: Case Report | First Published: April 15, 2022

Apixaban is an oral anticoagulant that directly inhibits Factor Xa and is indicated for the prophylaxis and treatment of deep venous thrombosis and stroke prevention in nonvalvular atrial fibrillation. Acute lower extremity Posterior Compartment Syndrome is a rare complication of Apixaban use. We present a 78-year-old male with significant medical morbidities taking Apixaban for Atrial Fibrillation presenting with post-traumatic extensive hemorrhagic bullae on the left proximal pretibial region ...

 Open Access DOI:10.23937/2643-4474/1710105

Usage of Denosumab for Giant Cell Rich Tumors: A Case Study and Literature Review

Shivum Desai, BS, Jingya Miao, MS, Alice S Wang, BS and Omid Hariri, DO, MSc

Article Type: Case Study and Literature Review | First Published: April 20, 2022

Denosumab is a human monoclonal antibody to receptor activator of NF-κB ligand (RANKL), which has been FDAapproved for the management of giant cell tumor of bone. Here, we present a case of 21-year-old female with solid aneurysmal bone cyst (ABC) treated with denosumab for 6 months to date. The patient experienced positive outcomes as the result of denosumab therapy. Although the use of denosumab has been reported in a number of studies, its off-label use for treatment of ABC and other giant ce...

 Open Access DOI:10.23937/2643-4474/1710099

Surgical Implications of Internal Jugular Stenosis in a Patient Undergoing Resection of a Craniocervical Junction Meningioma

Catherine Zhang, Lauren Harris, Hamza Itum, Sanjiv Chawda, Julian Coker, Jonathan Pollock, Ahmed Sadek and Shoakazemi

Article Type: Case Report | First Published: March 05, 2022

Internal jugular vein (IJV) stenosis is being increasingly associated with certain neurological conditions, including benign intracranial hypertension, cerebrospinal fluid (CSF) disorders, multiple sclerosis and Alzheimer’s disease. The role of surgery in IJV stenosis have typically been to manage the associated CSF disorders, or with IJV stents. We describe a case of a patient incidentally found to have bilateral possible IJV stenosis with dilated paraspinal collateral venous channels during ...

 Open Access DOI:10.23937/2474-3658/1510257

Role of Clinical, Laboratory, and Radiological Manifestations in Prognostication of COVID-19 in 804 Patients Admitted to Three Tertiary Care Centers in Dubai, United Arab Emirates

Rommana Mehdi, Arshee Khan, Priyank Gupta, Aisha Siddiqui, Anam Ahsan, Mona Hosseini, Farah Ghayoor, Jawahir Tahir, Samya Javed, Saubia Fathima, Zufana Nasir, Hana Mohd Sughaiyer, Erum Rehman, Nimmi Moni, Salama Buqaish, Eman Abdelwahed, Deema Harb, Beyla Zuberi and Laila AlDabal

Article Type: Original Research | First Published: April 20, 2022

December 2019 heralded the onset of the 2019 novel coronavirus (SARS-CoV-2) outbreak in the Hubei province in China. Ever since the disease has spread across continents resulting in rising magnitudes of cases and fatalities. SARS-CoV-2 is a beta coronavirus that belongs to the family Coronaviridae and order Nidovirales. Six coronavirus species have been identified to infect humans and cause mild disease so far; SARS-CoV-2 is the seventh member of the coronaviruses that infect humans. Fatal illne...

 Open Access DOI:10.23937/2474-3658/1510256

Prevalence of Diminished Vitamin D and Association between Vitamin D-Levels and Morbidity by Acute Respiratory Infections (ARI) among Hospital Staff in Northern Bavaria during a Seasonal Flu Epidemic

Michael Holbach, MPH and Bernd Seese

Article Type: Original Research | First Published: April 15, 2022

Although vitamin D is known to have an influence on the immune system, the impact of a low level on the susceptibility to ARI is not very clear. So the aim of this study was to investigate the prevalence of diminished vitamin D in adult workers and the relationship between vitamin D-levels and the morbidity of acute respiratory infections (ARI) during the influenza epidemic in the first quarter of 2018 (Q1/2018) in Germany. Included were 60 employees of a hospital in northern Bavaria. Immediatel...

 Open Access DOI:10.23937/2469-5793/1510146

Addressing HIV Drug Shortage in Kenya: A Crucial Action

Oladunni Amos Abimbola, Olajide Edward Olorunfemi, Alaka Hassan Olayemi, Odususi Oluwatomisin Dara, Haruna Usman Abubakar, Bamidele Opeyemi Olufunso and Jackson Safari Kilonzo

Article Type: Commentary | First Published: April 24, 2022

HIV/AIDS is one of the major public health concerns worldwide. The African region is the most affected worldwide, with Kenya being the joint sixth largest epidemic in the region. Kenya’s health system is characterized by donor reliance and donor concentration. As a result, key national strategic programs including HIV program are significantly funded by foreign aid. While the challenge of insufficient internal funding has relatively being cushioned by external support, Kenya’s transition fro...

 Open Access DOI:10.23937/2469-5750/1510113

Chronic Psoriasis with Vulvar Presentation: A Case Report

Nathan Joshua Manales, BS, Maricela Chavez, MD, MS, Miriam Shayeb, MS and Gary Ventolini, MD

Article Type: Case Report | First Published: April 18, 2022

Psoriasis is a fairly common chronic skin condition that presents itself as erythematous, itchy patches with the most commonly affected areas being the elbows, knees, buttocks, scalp, and sites of trauma. Psoriasis of the genitals affects less than half of those diagnosed with psoriasis and can cause major discomfort and frustration. This case report aims to highlight as well as to help discern the presence of vulvar psoriasis among other causes. This report describes a patient with chronic psor...

 Open Access DOI:10.23937/2572-3286.1510070

Cocaine Induced ANCA Negative Vasculitis - A Diagnostic Dilemma!

Kunal Bhuta, Kriti Devkota2 and Haris Mobeen

Article Type: Case Series | First Published: April 24, 2022

Cocaine is an addictive stimulant drug. In 2014, about 913,000 Americans met the Diagnostic and Statistical Manual of Mental Disorders criteria for dependence or abuse of cocaine. Approximately 69% of Cocaine has been contaminated with Levamisole. Levamisole has been found to be immunogenic causing anti-neutrophil cyto-plasmic antibody (ANCA)-associated cutaneous vasculitis in 88-100% patients. 24-year-old male with a history of polysubstance abuse including IV drug abuse presented with complain...