Open Access DOI:10.23937/2469-5696/1410077

The Severity of Sickle Cell Anemia in Men - The Action of Molecular and Biochemical Markers

Jonathan de Oliveira Rios, Thais Fernandes Ribeiro, Gabriel Felipe Arantes Bertochi, Clarisse Lopes de Castro Lobo and Claudia Regina Bonini Domingos

Article Type: Original Article | First Published: June 23, 2022

Sickle cell disease is characterized by a very heterogeneous clinical course among patients with the same mutations for sickle cell hemoglobin (HbS). Sickle cell anemia (SCA) is a hereditary hemoglobinopathy caused by the homozygosity of a point mutation in the beta-globin gene, which leads to the substitution of glutamic acid for valine in the sixth position....

 Open Access DOI:10.23937/2469-5866/1410042

Juvenile Stroke in a Patient with Severe Large Vessel Atherosclerosis of the Neck Decades after Radiotherapy for Nasopharyngeal Carcinoma: Are Iatrogenic Endocrinopathies Additional Risk Factors?

Ruggiero Leone, Sergio Altomare, Maria Stella Aniello, Daniele Liuzzi, Immacolata Plasmati, Michele Sardaro, Maria Superbo, Daniela Tato, Rosella Carpentiere, Giuseppe Guglielmi and Maurizio Giorelli

Article Type: Case Report | First Published: June 20, 2022

Juvenile Nasopharyngeal carcinoma (NPC) is a rare head and neck cancer in Western Countries. Neck radiotherapy (RT) is a routine procedure for treating or preventing the nodal metastasis in NPC patients. Ionizing radiation from RT has been associated with enhanced atherosclerotic process of large vessel arteries of the neck and brain which results in higher incidence of cerebrovascular events....

 Open Access DOI:10.23937/2643-4512/1710080

Prevalence of Ear Infections in Children (0 to 15 Years) of India: A Systematic Review and Meta-Analysis

Ragini Bhatia, Anil Chauhan, Kulbir Kaur, Monika Rana, Pranita Pradhan and Meenu Singh

Article Type: Original Article | First Published: June 23, 2022

In this review PRISMA guidelines (preferred reporting items for systematic reviews and meta-analysis) were followed. We did extensive literature search in PubMed, Embase, Cinahl and Web of Science to identify relevant community based cross sectional studies that investigated the prevalence of ear diseases in children in India. We used STATA version 16.0 software to perform meta-analysis....

 Open Access DOI:10.23937/2643-4512/1710078

Attitudes and Barriers towards Adolescent Sexuality and Abortion Care in the Northern Part of Ghana

Alhassan Abibata, Musah Nihayatu, Joseph Owusu-Marfo, Ruth Nimota Nukpezah and Yaa Nyarko Agyeman

Article Type: Research Article | First Published: June 15, 2022

The adolescence period is generally perceived as being healthy, however, most adolescents in the Tamale Metropolisgo through this period with health challenges such as sexual and reproductive problems and unsafe abortion. This study aimed to determine the attitude and barriers toward Adolescent Sexuality and abortion in the Tamale Metropolis....

 Open Access DOI:10.23937/2378-3656/1410395

Methotrexate Induced Stevens-Johnson Syndrome: Two Cases Reports

I. Masmoudi, F. Baklouti, N. Siala, YO. Yaye, A. Masmoudi and A. khanfir

Article Type: Case Report | First Published: June 23, 2022

Methotrexate induced Stevens-Johnson syndrome (SJS) is rare but life-threatening cutaneous reaction. This is a case report of two 14-year-old girls with methotrexate (MTX)-induced Stevens-Johnson syndrome (SJS). Both girls received chemotherapy with MTX in the treatment of osteosarcoma and then developed SJS....

 Open Access DOI:10.23937/2469-5726/1510096

A Children's Tale: Unusual Presentation of Juvenile SLE

Naisar Dilip Nahar and Prachi Naisar Nahar

Article Type: Case Report | First Published: June 16, 2022

Paediatric systemic lupus erythematosus (pSLE) is an autoimmune disease with multiple manifestations resulting in inflammation & damage to several organs. We report a case of young boy presented to us with features of meningoencephalitis with multisystem involvement....

 Open Access DOI:10.23937/2474-3658/1510267

Tigecycline-Induced Clinical Jaundice: A Case Report and Review of the Literature

Sarah Ali Althomali

Article Type: Case Report | First Published: June 17, 2022

Tigecycline gained large popularity due to its efficacy against multi-drug-resistant organisms. Tigecycline has a good safety profile, and its most encountered side effects are nausea, vomiting and diarrhea. However, tigecycline has been associated with a mild and transient hepatotoxicity....

 Open Access DOI:10.23937/2474-3658/1510266

Evaluation of the Quality of Malaria Case Management at a Rural Health Facility in the Savannah Region of Ghana

Joseph Owusu-Marfo, Yaa Nyarko Agyeman, Augusta Soninour Kolekang, Samuel Bimpong and Abdul Manan Sumani

Article Type: Research Article | First Published: June 17, 2022

Malaria remains a major public health issue in the world especially in the resourced-limited countries. Ghana is not left out as the incidence of malaria still accounts 40% of all OPD cases....

 Open Access DOI:10.23937/2474-3658/1510265

Guillain-Barre Syndrome Post-COVID 19 Vaccination with Sinovac CoronaVac in a 59-Year-Old Male: First Reported Case in the Philippines

Bello Marq Wilson, MD and Aguirre Amador III

Article Type: Case Report | First Published: June 17, 2022

COVID-19 pandemic has severely disrupted our lives, wrecking havoc in our economies and pushing the healthcare sector to its breaking point. This prompted world governments to come up with different measures and protocols in the hope of containing and preventing the further spread of the COVID-19 virus....

 Open Access DOI:10.23937/2474-3658/1510264

Factors Affecting Tuberculosis Case Detection in Kwahu East District of the Eastern Region, Ghana - A Health Facility-Based Cross-Sectional Study among TB Patients

Mukasa Kabiri, Anthony Agamba, Paul Kofi Awuffor, Helena Sakyibea Darkwa, Kortey Larweh, Kenneth Owusu Frimpong and Ayenor Michael

Article Type: Original Research | First Published: June 16, 2022

Tuberculosis is ranked the second cause of mortalities in the world only behind the deadly COVID-19. The disease is very communicable especially in poorly ventilated environments and crowded places. High risk of transmission from patients to health workers and then to the general population has been a great worry for the tuberculosis control programme worldwide....