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© 2018 Napoli A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

ORIGINAL ARTICLE | OPEN ACCESS DOI: 10.23937/2377-9004/1410131

Uterus-Sparing Treatment Options for the Management of Fibroids

Alessandro Napoli1, Roberto Scipione1, Hans-Peter Erasmus1*, Cristina Marrocchio1, Susan Dababou1, Fabrizio Andrani1, Carola Palla1, Michele Anzidei1, Federica Ciolina1, Lucia Manganaro1, Delia Savone2, Ludovico Muzii2, Francesco Pecorini2 and Carlo Catalano1

1Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Italy

2Department of Gynecology-Obstetrics and Urology, Policlinico Umberto I, Sapienza University of Rome, Italy


Currently, different treatment options are available in the management of uterine fibroids: Medical therapy aims at relieving symptoms, while semi-invasive or non-invasive procedures aim to treat symptoms and eventually to reduce the fibroids' size. A wide spectrum of treatments may be confusing to implement correctly, and the gynecologist should be familiar with the features of each procedure, to provide a personalized therapy, with each patient being directed towards the most suitable therapeutic option according to her specific characteristics. A thorough knowledge of the properties of each therapeutic strategy is fundamental for a correct orientation of the specialist in the management of symptomatic uterine fibroids; the final purpose has to be the establishment of an individual-centered care system, within each woman will be addressed by the most suitable among the available treatment options. This work provides a panoramic view of the main available uterus-sparing strategies for the management of symptomatic fibroids (with particular attention on specific indications, patient selection, advantages and adverse events), as well as a practical and comprehensive guide for the choice of the most appropriate option.