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Clinical Medical Image Library

Sub-RPE Desposits - Ex Vivo Hyperspectral Autofluorescence (AF) Image of Drusen from 84-Year-Old Male Donor with late Age-Related Macular Degeneration

R. Theodore Smith*, Tal Ben-Ami and Yuehong Tong

New York University, Department of Ophthalmology, Newyork, USA

*Corresponding author: R. Theodore Smith, New York University, Department of Ophthalmology, 550 First Avenue, New York, NY 10016, USA, Tel: 212-263-7300; E-mail:
Clin Med Img Lib, CMIL-1-008, (Volume 1, Issue 1); ISSN: 2474-3682
Published Date: August 25, 2015
Citation: Smith RT, Ben-Ami T, Tong Y (2015) Sub-RPE Desposits - Ex Vivo Hyperspectral Autofluorescence (AF) Image of Drusen from 84-Year-Old Male Donor with late Age- Related Macular Degeneration. Clin Med Img Lib 1:008
Copyright: © 2015 Smith RT. This is an open-access content distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

The image is an overlay of 3 images representing the distribution of the 3 most abundant fluorophore signals that were extracted using advanced factorization algorithms. The 3 images were digitally colored red (1), green (2) and blue (3). The signals localized to different components in the RPE as illustrated by color mixing: RPE Cells (azure), sub-RPE deposits (pink). This method demonstrates that distinct fluorophore signals are localized to sub-RPE deposits in AMD tissues.

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