International Journal of

Rare Diseases and DisordersISSN: 2643-4571

Archive

 Open Access DOI:10.23937/2643-4571/1710058

Craniofacial Fibrous Dysplasia: Is Alkaline Phosphatase an Accurate Marker of Disease Activity?

Wyatt Nice, Kezia Daniel, Kathleen Brindle and Rodolfo Curiel

Article Type: Case Report | First Published: 2024/02/10

Fibrous dysplasia is a rare benign bone condition in which mature bone is replaced with fibrous tissues. Disease activity is most prominent in the first three decades of life before becoming inactive. Elevations in alkaline phosphatase have been known to be present during times of active disease, however, the clinical utility of using alkaline phosphatase to monitor disease progression remains unclear. We present the case of a 72-year-old woman with a history of craniofacial fibrous dysplasia cl...

 Open Access DOI:10.23937/2643-4571/1710057

Navigating Rarity: Extranodal Presentation of Castleman Disease

Kovuri Umadevi, Lavanya Motrapu, Mohd Imran Ali and Rajarikam Nagarjunachary

Article Type: Case Report | First Published: 2024/01/27

Castleman disease (CD) is a rare lymphoproliferative disorder, originally described by Dr. Benjamin Castleman, characterized predominantly by enlarged mediastinal lymph nodes with unknown etiology. While it commonly affects mediastinal lymph nodes, occurrences in neck lymph nodes are less frequent, and presentation in the extremities is exceptionally rare. This report presents a case of a 55-year-old female with a 15-year history of a solitary swelling in her right arm. ...

Volume 7
Issue 1