Statins are a widely used class of drugs that have been found to be safe and effective in treating hypercholesterolemia. Statin-associated muscle symptoms (SAMS) are a clinical spectrum defined as muscle pain, discomfort, and/or weakness with or without elevated CK levels. This spectrum ranges from more common minimal myalgias to rare, severe statin-associated immune-mediated necrotizing myopathy (IMNM)....

The patient had an atypical presentation of Guillain- Barre syndrome (GBS) with descending muscle weakness and paralysis that started at the upper extremities and progressed to the lower extremities in contrast to a typical ascending infection that usually starts at the lower extremities. Hyporeflexia of deep tendon reflexes of the affected extremities was also present....