Open Access DOI:10.23937/2572-4061.1510035
A Comprehensive Assessment of Hepatotoxicity Induced by Engineered Nanoparticles- A Review
S V S Rana
Article Type: Review Article | Indexed Archive: Volume 6
Liver is the major detoxifying centre of the body. It removes xenobiotics and their metabolites through metabolism or biliary excretion. Hepatocytes constitute 80% of total liver mass and play a major role in storage, synthesis, metabolism and redistribution of essential molecules. Liver has been known to accumulate > 90% of nanomatrerials translocated from other organs. Bioconcentration of nanoparticles may lead to impairment of structure and function of hepatic cells. Therefore, it is critical...
Open Access DOI:10.23937/2572-4061.1510034
Psychological Impact of Medical Professionals Handling COVID-19 Patients in Hospitals
Anirban Biswas, Saroni Biswas and Arijit Bhowmik
Article Type: Research Article | Indexed Archive: Volume 6
COVID-19 pandemic became a death troll and cause of unbearable psychological pressure for all and the pandemic situation has been considered as a national disaster in India. Present study identified the mental health status of the medical professionals in different hospitals handling COVID-19 patients. We collected psychological data of medical professional using online questionnaire and identified their psychological status following three tools namely, Generalized Anxiety Disorder (GAD), Depre...
Open Access DOI:10.23937/2572-4061.1510033
Quantification and Risk Assessment of Heavy Metals in Groundwater and Soil of Residential Areas around Awotan Landfill, Ibadan, Southwest-Nigeria
Olagunju TE, Olagunju AO, Akawu IH and Ugokwe CU
Article Type: Original Article | Indexed Archive: Volume 6
Non-sanitary landfill poses enormous threats to lives. In this study, heavy metals in groundwater and soil of residential areas around Awotan landfill, Ibadan, Southwest-Nigeria were quantified and associated environmental and health risks were assessed within 1-150 m and 151-300 m radii. A total of 20 samples of groundwater and soil each were analysed for Pb, Cd, Cr, Ni, Cu, Fe and Zn using Atomic Absorption Spectrometry (AAS). Pb was above the WHO permissible limit in groundwater while Cd was ...
Open Access DOI:10.23937/2572-4061.1510032
Reference Dose and Reference Concentration Rounding in IRIS: Risk Assessment Ramifications
Lawrence V Tannenbaum
Article Type: Original Article | Indexed Archive: Volume 6
Commonly, reference doses and reference concentrations, toxicity factors supporting non-cancer assessments for the chemical exposures of humans, are rounded values. While the U.S. EPA's Integrated Risk Information System rather evidently employs this rounding practice so as to arrive at toxicity values that are uniform and simple in appearance, the particulars of the rounding approach are only loosely discussed. The analysis provided here found that reference dose and reference concentration rou...
