Open Access DOI:10.23937/2572-4045.1510067
Posttransplant Cutaneous Anaplastic Large Cell Lymphoma
Najoua Ammar, Mariame Meziane, Nadia Ismaili, Laila Benzekri and Karima Senouci
Article Type: Original Article | First Published: March 09, 2023
Post-transplant lymphoproliferative disorders (PTLD) are frequent in organ recipients; they are most often of B lymphocyte origin; on the other hand, CD30+ t-cell PTLD remain rare; we report the observation of a case of CD30+ anaplastic large cell lymphoma in a renal transplant recipient....
Open Access DOI:10.23937/2469-5769/1510113
Appearance of Bronchiolitis in Children with Congenital Heart Disease
Randriamanga RLiD , Rakotomalala RLH, Rakotomamonjy HL and Robinson AL
Article Type: Research Article | First Published: March 23, 2023
Bronchiolitis is a viral respiratory infection that is usually mild in infants less than one-year-old but can be serious and fatal in children with underlying heart disease. Our objective was to describe the epidemiological - clinical, therapeutic and evolutionary aspect of the bronchiolitis and heart disease association seen at the Tsaralalàna mother child hospital center. This was a retrospective case-control study over a 5-year period from January 2016 to January 2021; 1 case was matched to ...
Open Access DOI:10.23937/2469-5769/1510112
Trends and Non-Clinical Predictors of Respiratory Syncytial Virus (RSV) and Influenza Diagnosis in an Urban Pediatric Population
Marina Oktapodas Feiler, PhD, MS, Recai Yucel, PhD, Zhiqing Liu, Mary Caserta, MD, B. Paige Lawrence, PhD, Carter H Pason, Dwight J Hardy, PhD, Kelly Thevenet- Morrison, MS, Ann Dozier, PhD, MS and Todd A Jusko, PhD, MS
Article Type: Original Manuscript | First Published: March 05, 2023
To evaluate the demographic, maternal, and community-level predictors of pediatric respiratory syncytial virus (RSV) and influenza diagnosis among an urban population of children residing in Rochester, NY. A test-negative case-control design was used to investigate various non-clinical determinants of RSV and influenza diagnosis among 1,808 children aged 0-14 years who presented to the University of Rochester Medical Center (URMC) or an affiliated health clinic in Rochester, NY between 2012-2019...
Open Access DOI:10.23937/2377-3634/1410167
Remission of Type 2 Diabetes with High-Fiber, Low-Fat, and Calorie Restricted Plant-Based Diet Study
Gunadhar Panigrahi, MD, FACC, DipABLM
Article Type: Clinical Research | First Published: March 11, 2023
Type 2 Diabetes (T2D) is a chronic progressive disease, and its prevalence is on the rise around the world. Despite advances in pharmacotherapy, mitigating the burden of the disease on individuals, societies and the healthcare system remains a challenge. Remission has emerged as a therapeutic target in T2D with wide range of interventions. A plant-based diet seems to be promising to achieve this goal. The present study is conducted to establish the feasibility of achieving remission of type 2 di...
Open Access DOI:10.23937/2377-3634/1410166
High Rate of Mortality in Children and Youth with HIV Infection Compared to those with Diabetes in Tanzania
Edna S Majaliwa MD, MMED, FESPE, Joel Ndayongeje BSC, MSC MPh, Kaushik Ramaiya MBBS, MMED, Blandina T Mmbaga MD, MMED, PhD and Sayoki G Mfinanga MD, PhD
Article Type: Original Article | First Published: March 11, 2023
Pediatric and youth diabetes mellitus (DM) and pediatric and youth human immunodeficiency virus (HIV) infection are among the chronic diseases with significant public health implications and high mortality. The availability of mortality statistics in type 1 diabetes and HIV/AIDS is critical for addressing the two conditions in one setting. To compare the mortality of children and youth living with Diabetes (CYLDM) versus children and youth living with HIV (CYLHIV)....
Open Access DOI:10.23937/2378-3419/1410179
Punicic Acid Inhibits Proliferation and Induces Apoptosis in Human MCF-7 Breast Cancer Cells
Oluwafemi Gbayisomore, Hannah Klausner and Shelley A Phelan, PhD
Article Type: Research Article | First Published: March 08, 2023
One of the main components of Pomegranate Seed Oil is punicic acid, an omega-5 fatty acid that is capable of inhibiting breast and prostate cancer cell proliferation, although the mechanisms of action are not yet known. In order to further understand its potential anti-cancer properties, we investigated the effect of punicic acid on proliferation and cytotoxicity of human MCF-7 breast cancer cells. Cells were treated with punicic acid for up to 72 hours, and cell proliferation, cytotoxicity, and...
Open Access DOI:10.23937/2643-4512/1710088
Building an Adult Congenital Heart Disease Unit in Colombia, a Comprehensive Model of Specialized Care for a Growing Population
John Jairo Araujo, MD, MBBS, Mst, NBE, FSIAC, FSISIAC, FACC
Article Type: Review Article | First Published: March 22, 2023
Adults with congenital heart disease are a growing population in Colombia and worldwide. Currently, Colombia has a population of more than 51 million inhabitants, with 38.2 million adults, 115,000 of whom live with congenital heart disease of varying complexity. The demographic profile shows that this population with congenital heart disease is mostly young, with ages ranging from 20 to 44 years. Keeping them in optimal health is a challenge, and care involves centralization in special adult con...