Open Access DOI:10.23937/2378-3656/1410017

A Case of Hematogenous Spread of E. coli causing Clinical Chorioamnionitis

Anne Kennard, Michael R. Foley and Jordan Perlow

Article Type: Case Report | First Published: February 25, 2015

This case report details a case of chorioamnionitis via hematogenous spread of bacteria following a perforation of the small bowel. Chorioamnionitis is typically thought of as an ascending infection so this case serves as a reminder that intraamniotic infection can arise from multiple sources including bacteremia. The signs and symptoms may be the same as a typical intraamniotic infection, however, may require different treatment due to the different route and pathogens associated with hematogen...

 Open Access DOI:10.23937/2378-3656/1410016

Outcomes of Influence of Dimethylarginine Derivats, PAD Isoenzymes, or both as Hallmark on Citrullinisation Process on Autoantigens ACPA/ Anti CCP Antibodies overall for Diagnosis in Rheumatoid Arthritis

Dejan Spasovski and Tatjana Sotirova

Article Type: Review Article | First Published: February 26, 2015

When establishing new diagnostic method for detection of the endothelial dysfunction in Rheumathoid Arthritis (RA), it is necessary to compare the diagnostic values with other laboratory variables. Aim: To Assess Asymmetric Dimethylarginine (ADMA) in RA and study its relation to ACPA and different clinical and laboratory parameters of disease activity in early non treated RA patients....

 Open Access DOI:10.23937/2378-346X/1410014

Long-Term Efficacy of Infliximab for Treatment of Severe Behcet's Uveitis

Emanuela Interlandi, Pietro Leccese, Ignazio Olivieri and Loredana Latanza

Article Type: Research Article | First Published: February 26, 2015

Medical records of 32 patients (56 eyes) were retrospectively analysed. Primary outcomes included ocular inflammatory activity, frequency of uveitis attacks and steroid-sparing effect. Results: Mean follow-up was 33,2 months while mean age of patients at disease onset was 33,3 years. Ocular inflammation was bilateral in 75% of cases and consisted in panuveitis in 46,4% of affected eyes....

 Open Access DOI:10.23937/2469-5726/1510007

Individualized Rheumatoid Arthritis Patient Care Means more than Achieving a Number

Burkhard F. Leeb

Article Type: Commentary | First Published: March 03, 2015

The therapeutic scope of inflammatory rheumatic diseases and of Rheumatoid Arthritis (RA) in particular, has increased dramatically over the last twenty years leading to incredibly better chances for the patients. Simultaneously disease activity assessment has become more and more important, not only to document the patient's disease course, but also for justifying the application of potentially dangerous and expensive remedies....

 Open Access DOI:10.23937/2378-3397/1410018

QOL of the Patients with Lymph Edema: Evaluation of Japanese Patients using SF-36

Makoto Hikosaka, Fumio Onishi, Masayoshi Takayama, Eri Konno and Kazuo Kishi

Article Type: Research Article | First Published: February 27, 2015

Purpose: This cross-sectional study aimed at evaluating the health related quality of life (QOL) of Japanese patients with lymphedema. Methods: A cross-sectional, descriptive study was conducted. Twenty-seven patients with lymphedema of the upper or lower limb(s) who presented the two institutions between January and December 2010 completed the Short Form 36 (SF-36: a generic health-related QOL measure)....

 Open Access DOI:10.23937/2377-3634/1410024

Assessment of Circulatory Levels of Endothelin-1 in Diabetic Subjects Screened Through a Cross Sectional Study from Rural Women in Bangladesh

Md. Arifur Rahman, Subrina Jesmin, Chishimba Nathan Mowa, Farzana Sohae, Junko Kamiyama, AKM Ahsan Habib, Nobutake Shimojo, Md. Majedul Islam, Masao Moroi, Osamu Okazaki, Naoto Yamaguchi, Satoru Kawano, Taro Mizutani and Yoshio Iwashima

Article Type: Research Article | First Published: February 26, 2015

Endothelin-1 (ET-1), a potential marker of endothelial dysfunction, has been shown to be elevated in diabetic mellitus (DM) subjects. However, to date, the circulatory profile of ET-1 and its association with DM have not been investigated in any South Asian country, including Bangladesh. The present study assessed circulating levels of ET-1 in subjects with or without DM and further examined the association of ET-1 with clinical and metabolic parameters in Bangladeshi rural women....

 Open Access DOI:10.23937/2377-3634/1410023

An Oral Antioxidant Formulation Delaying and Potentially Reversing Canine Diabetic Cataract: A Placebo Controlled Masked Pilot Study

David Williams, Angus Fitchie and Carmen Colitz

Article Type: Clinical Trial | First Published: February 24, 2015

The majority of dogs with diabetes mellitus develop blinding mature cataracts through the action of the enzyme aldose reductase producing sorbitol with osmotic action drawing water into the lens thus causing opacification. ...

 Open Access DOI:10.23937/2377-9004/1410025

Expectant Management in Cesarean Scar Pregnancy

Natasha Gupta

Article Type: Letter | First Published: February 27, 2015

The incidence of pregnancy implantation at unusual sites like cesarean scar, cervix or ovaries is on rise due to the increase in incidence of cesarean sections, dilatation and curettages and pelvic inflammatory diseases. Diagnosis of these rare types of ectopic pregnancies is extremely challenging. Cesarean scar ectopic pregnancy as well as cervical pregnancy can be easily confused with each other or with an inevitable abortion....

 Open Access DOI:10.23937/2377-9004/1410024

The Outcome of TVT-O Procedure with Cough Test in Theatre under Local Anaesthesia and Sedation in Women with or without Intrinsic Sphincter Deficiency: Retrospective Case Series of 111 Women

Nader Gad, Basia Slusarczyk, Brooke O'Brien and Andrew Mitchell

Article Type: Case Report | First Published: February 23, 2015

Aim: To assess the outcome of TVT-O procedure performed under local anaesthesia and sedation, with a cough test, on patients with urodynamic stress urinary incontinence with or without intrinsic sphincter deficiency. Methods: A retrospective cohort study analysing the outcomes of 111 women between December 2004 and April 2013. The primary outcome was the resolution of stress urinary incontinence....

 Open Access DOI:10.23937/2378-346X/1410013

Systemic Rituximab for Conjunctival Marginal Zone (Malt) Lymphoma is not Protective for Subsequent Disease Development in the Contralateral Eye

Konstantinos Kopsidas, Amit Arora, Karim Hammamji, Gordon Hay, Victoria M.L. Cohen, Mandeep S. Sagoo, John L. Hungerford and P. Nicholas Plowman

Article Type: Case Report | First Published: February 23, 2015

Purpose: We report a case of a 35-year old male who presented with unilateral conjunctival extranodal marginal zone (MALT) lymphoma and underwent systemic Rituximab immunotherapy as primary treatment. After an excellent initial response and four years of complete remission he presents with MALT lymphoma to the contralateral conjunctiva. Methods: MALT lymphoma is the most common lymphoid neoplasm of the conjunctiva, and has an indolent clinical course....