Open Access DOI:10.23937/2378-3656/1410019
Idiopathic Granulomatous Mastitis - A Great Mimic
Akash Virupakshaiah, Praneeth Pasam, Prachi Kala, Shilpa Lakkundi and Mayilvaganan Sabaretnam
Article Type: Case Report | First Published: February 28, 2015
Idiopathic Granulomatous Mastitis (IGM) is an uncommon breast disease often mistaken for breast infection, abscess or Carcinoma. Here are two cases of IGM diagnosed after prolonged ineffective treatment of presumed infectious mastitis with abscess and carcinoma. The diagnosis was confirmed by biopsy and the patients were further evaluated to exclude other causes that would present with granulomatous formation....
Open Access DOI:10.23937/2377-4630/2/1/1021
Airway Management following Facial Trauma Caused by a Pit Bull Attack
Jaime Ortiz and Kelly A. Frew
Article Type: Case Report | First Published: February 28, 2015
Airway management of patients following facial trauma poses many challenges to the acute care team. An 80 year old male presented following a pit bull attack with massive trauma to his face, scalp and extremities. After carefully considering the options available, we were able to safely secure his airway by utilizing a WuScope. We confirm that the WuScope is a useful tool for airway management in a case of severe facial trauma....
Open Access DOI:10.23937/2469-5793/1510001
Family Medicine and Disease Prevention: Core Topics for Modern and Healthy Society
Massimo Giangaspero
Article Type: Editorial | First Published: May 02, 2015
Family medicine is expression of societal needs in terms of health and welfare standards. From newborn to elderly, all single members of the family are primary subjects for health strategies. Family physicians, practitioners, researchers in the field of healthcare, medicine and general practice are directly involved in first line to ensure adequate sanitary standards and promote preventive measures....
Open Access DOI:10.23937/2378-3001/2/1/1023
Warfarin is Associated with Increased Intracranial Hemorrhage and Mortality in Patients with Ground Level Falls: A Retrospective Cohort Study
Stephen Stanek, Varun Gupta, Tahir Jamil, Christopher Clancy, Brett Aplin, Anthony Archual, Mallory Williams and William Olorunto
Article Type: Retrospective Cohort Study | First Published: February 27, 2015
Fall is the number one mechanism of injury for admissions to trauma centers across the US. The use of anticoagulation therapy has also increased significantly, particularly among the older population. We hypothesized that anticoagulation with warfarin increases the risk of intracranial hemorrhage (ICH) and death after a ground level fall. Methods: A retrospective cohort of all patients admitted to a level 1 trauma center, between 2008 and 2011, after a ground level fall was identified....
Open Access DOI:10.23937/2378-3001/2/1/1022
Pathogenesis of Multiple System Atrophy - Recent Developments
Kurt A. Jellinger
Article Type: Mini Review | First Published: February 27, 2015
Multiple System Atrophy (MSA) is a rare adult-onset neurodegenerative disorder of uncertain etiology, clinically manifesting with parkinsonism, cerebellar impairment, autonomic dysfunction and pyramidal signs. The pathological process affects striatonigral, olivopontocerebellar, and autonomic nervous systems. The major clinical variants correlate to the morphologic phenotypes of striatonigral degeneration (MSA-P) and olivopontocerebellar atrophy (MSA-C). Pathologically, MSA is characterized by G...
Open Access DOI:10.23937/2378-3656/1410018
Can Genetic Testing Provide Information to Develop Customized Nutrigenomic Solutions for Reward Deficiency Syndrome?
Kenneth Blum, Rajendra D Badgaiyan, Zsolt Demotrovics, James Fratantonio, Gozde Agan and Marcelo Febo
Article Type: Opinion | First Published: February 28, 2015
We are entering the era of genomic medicine and neuroimaging as it relates to addiction a subset of Reward Deficiency Syndrome. In 2005 our laboratory received the first USA patent on Nutrigenomics and RDS treatment. This was awarded on the basis of our earlier work showing anti-addiction activity of a nutraceutical consisting of amino-acid precursors and enkephalinase inhibition properties and our discovery of the first polymorphic gene (Dopamine D2 Receptor Gene [DRD2] to associate with sever ...