Open Access DOI:10.23937/2378-3516/1410025

Differentially Expressed Proteins in Response to Resuscitation of NonCulturable Cells of Mycobacterium tuberculosis H37Rv: Potential New Drug Targets

Ravi Kr. Gupta, Bhavnesh Kumar, Deepa Bisht, Kiran Katoch, Kalyan Mitra and Ranjana Srivastava

Article Type: Case Report | First Published: August 03, 2015

The major obstacle in TB eradication is attributed to the dormant state of the TB bacilli, Mycobacterium tuberculosis and is characterized by asymptomatic, non-culturability and antibiotic resistant state of disease. Conventional antibiotic therapy is only applicable to the active form of the disease. These non-replicating cells can resume the growth in immunosuppression state and cause the symptomatic disease....

 Open Access DOI:10.23937/2377-9004/1410056

Management of Spontaneous Rupture of the Amnion with an Intact Chorion

Jenny A. Jacob, Norman A. Ginsberg, Lee P. Shulman and Leeber Cohen

Article Type: Case Report | First Published: August 06, 2015

Idiopathic severe preterm oligohydamnios as a result of spontaneous rupture of the amnion with an intact chorion is a rare event with a scarcity of reports found in the literature. We evaluated the impact of serial amnioinfusions on this unusual occurrence. This is a followup of a 37-year-old woman with idiopathic severe oligohydramnios diagnosed at 18 weeks of gestation. We performed fie serial amnioinfusions with the purpose of improving fetal lung maturity and to prevent Potter anomalad. At 3...

 Open Access DOI:10.23937/2572-4215.1510003

Comparison of Bioelectrical Impedance Analysis and Magnetic Resonance Imaging for the Quantification of Fat Mass

Cuisle Forde, Niamh Murphy, James Meaney, Paul Kennedy, Gerard Boyle and John Gormley

Article Type: Original Research Article | First Published: August 17, 2015

Body composition is a key determinant of health. Many methods, including bioelectrical impedance analysis (BIA), are available to estimate body composition; however the validity of such methods varies greatly. The aim of this cross sectional study was to investigate the accuracy of the Tanita MC-180MA BIA machine in the quantification of fat mass through comparison with Magnetic Resonance Imaging (MRI)....

 Open Access DOI:10.23937/2378-346X/1410032

Surgical Management of Concomitant Ptosis and Cicatricial Entropion in a Patient with Ocular Cicatricial Pemphigoid

Scuderi G, Mutolo MG, Lambiase A and Recupero SM

Article Type: Case Report | First Published: August 22, 2015

A 71 year-old patient presented with vision impairment and pain in the right eye due to entropion associated with trichiasis and mild-ptosis. He had a history of ocular cicatricial pemphigoid together with a lung cancer of the apex of the right lung with pleural involvement. There was a history of central retinal vein occlusion of the left eye. Clinical and orthoptic examination was conducted and a decision was made to perform surgical correction of the entropion followed by correction of ptosis...

 Open Access DOI:10.23937/2378-3656/1410047

Does Assessment of Self-Regulated Learning and Metacognition in Surgical Residents Provide Insight to Performance on High Stakes Standardized Examinations? A Pilot Study

Jack Contessa, Tassos C. Kyriakides and Geoffrey Nadzam

Article Type: Research Article | First Published: August 14, 2015

The concept of lifelong learning has received widespread attention in the healthcare field and in numerous other industries due to the sheer volume of new and expanding knowledge and information continuously created by one hand and rendered obsolete by the other. As a result, physicians need to be engaged in lifelong learning to improve, expand, and maintain mastery of their knowledge, skills, and competencies....

 Open Access DOI:10.23937/2378-3656/1410046

Some Diagnostic Aspect on Abnormal Nitric Oxide Metabolism and Some Pharmacological Aspects of the most used Drugs in Rheumatoid Arthritis

Dejan Spasovski

Article Type: Research Article | First Published: July 31, 2015

Introduction: To evaluate the diagnostic test for Assymetric Dimethyl Arginine (ADMA), Rheumatoid factor (RF), C-reactive protein (CRP), Disease Activity Score with 28 joint ( DAS 28 index ), and to define the effect of untreated rheumatoid arthritis on endothelial function. In order to determine whether ADMA changes depending on the disease evolution, ADMA was used as an indicator for endothelial dysfunction in subclinical atherosclerosis Methods: Using a ELISA technology of DLD-Diagnostika-GMB...

 Open Access DOI:10.23937/2377-9004/1410055

The Case of 11w+ 2d Fetal Heart Rate Positive Unruptured Cervical Pregnancy

Onder Sakin, Bulent Kars, Ilke Tanir and Omer Talip Turhan

Article Type: Case Report | First Published: August 05, 2015

The treatment of cervical pregnancy which is one of the rarest forms of ectopic pregnancy is one of the cases difficult decisions need to be taken. Many years ago when hysterectomy was the only treatment and in case of late treatment decision, 50% of maternal mortality was seen, which results in a change of status with the shape of the high-risk pregnancies' extremely minimal invasive treatment may be possible Moreover, the patient fertility will be preserved and hysterectomy and the negative si...

 Open Access DOI:10.23937/2474-1353/1510001

Spontaneous Ruptured Heterotopic Fallopian Tube Pregnancy: A Challenging Case

Olga Grechukhina, Diana P. English, Wei Hong, Ravi Kaza and Elena Ratner

Article Type: Case Report | First Published: August 09, 2015

This is a case of a 39 year old gravida 4 para 2-0-1-2 patient who presented to the emergency room with 1 week history of worsening left sided abdominal pain associated with vaginal bleeding. She had a positive pregnancy test and transvaginal ultrasound demonstrated an 11x9x7cm retrouterine mass concerning for hemorrhagic debris but no adnexa were identified. Surgery was complicated by conversion from laparoscopy to low transverse laparotomy due to hemorrhage and severe adhesive disease. Both tu...

 Open Access DOI:10.23937/2378-3516/1410024

Discharge Care Bundle for Patients with Acute Exacerbations of COPD: Benefit more likely to be seen beyond 30 Days

Shorofsky M, Lebel M, Sedeno M, Zhi Li P and Bourbeau J

Article Type: Original Article | First Published: August 03, 2015

Background: COPD is associated with significant morbidity, mortality, and hospital costs. The implementation of COPD 'discharge care bundles' has been proposed as having an impact on readmissions. We developed and implemented a discharge care bundle and the aim of this study was to evaluate its effects on utilization of hospital services in a real life setting. Methods: We conducted a retrospective chart review study from 2007-2013 to evaluate utilization of hospital services over three time per...

 Open Access DOI:10.23937/2474-3631/1510007

Ethical Issues Surrounding In-Patient Treatment for Adolescents with Substance Use Disorders

Audra Roemer

Article Type: Review Article | First Published: August 12, 2015

The following article reviews the literature on ethical issues surrounding in-patient treatment of adolescents with substance use disorders. Ethical issues surrounding confidentiality, informed consent, competency, multiple relationships and boundaries, working on a multi-disciplinary team, responsible caring, and termination of services are discussed. There is a gap in the literature regarding the ethical issues associated with this specific population; however, given the sensitive nature of th...