Open Access DOI:10.23937/2474-1353/1510016
Parental Bonding and Adult Attachment Style: The Relationship between Four Category Models
Kay Wilhelm, Inika Gillis and Gordon Parker
Article Type: Research Article | First Published: March 16, 2016
Early relationships formed between parent and child are thought to guide the child's feelings, thoughts and expectations in subsequent adult relationships. We examined the relationship between two four category models of perceptions of parenting and adult attachment style among a nonclinical cohort. Parenting style was assessed using the Parental Bonding Instrument (PBI) and adult attachment, using the Relationship Questionnaire (RQ)....
Open Access DOI:10.23937/2474-1353/1510015
Women's Experiences in Accessing Reproductive, Maternal, and Child Healthcare Services in the Mopti Regions of Mali
Filio Degni, Brahima A. Diallo, Walid El Ansari, Reija Klemetti and Kathleen Valtonen
Article Type: Research Article | First Published: March 14, 2016
Mali is one of the West African nations facing public health challenges. The country ranks among the top 10 countries in which women face the highest risk of death during pregnancy and childbirth. Particularly during the armed conflict in 2012, in the northern regions of Mali, healthcare services were destroyed and afterwards the healthcare centers were no longer able to run in the normal way. Women's access to health services became a critical issue in those regions....
Open Access DOI:10.23937/2378-3656/1410095
Socket Reconstruction after Firework Explosion Injury
Reili Rebane, Mari Tamsalu and Artur Klett
Article Type: Case Report | First Published: March 14, 2016
We report a challenging case of orbital socket reconstruction. A 49- year-old man presented two weeks after fireworks exploded in his face. He had multiple orbital bone fractures on the right and the globe was enucleated because of severe damage. No primary orbital implant was used due to infection risk. One month after the trauma he suffered from infection of the conjunctival sac and periorbital skin despite initial intravenous and oral antibiotics. Because of inability to wear a cover shell ey...
Open Access DOI:10.23937/2378-3656/1410094
Atypical Presentation of Madelung Disease
Maisel Lotan Adi, Retchkiman Meir and Gronovich Yoav
Article Type: Case Report | First Published: March 09, 2016
We present a unique case of a sixty two year old woman with symmetric lipomatosis of the lower back, similar to cup C female breast. Lipoma is the most common type of soft tissue mesenchymal tumor. Lipoma is commonly found in the upper back, neck, shoulder and abdomen, and rarely in the face, hands or feet. When lipomatosis is symmetrical it is often termed Multiple Symmetrical Lipomatosis (MSL), also known as Madelung disease, a rare syndrome of unknown etiology....
Open Access DOI:10.23937/2469-5734/1510025
Partial-mouth Periodontal Examination Protocols for Population-based Surveillance of Periodontitis
Duong T Tran, Isabel C Gay and Muhammad F Walji
Article Type: Research Article | First Published: February 16, 2016
Using the CDC/AAP definition, the ranges of relative bias of moderate and severe periodontitis prevalence were 6.8% to 18.1% and 28.4% to 41% in absolute value for the PMPE protocols, respectively. With half-reduced CDC/AAP definition, half-mouth four-site protocol provided small absolute bias (4.2%) and relative bias (11.4%) for the estimates of moderate periodontitis prevalence; corresponding biases for severe periodontitis were -1.1% and -8.2%....
Open Access DOI:10.23937/2378-3419/3/2/1048
New Enzyme-Targeting Radiosensitizer (KORTUC) Containing Hydrogen Peroxide & Sodium Hyaluronate for Intra-tumoral Injection Using Mice Transplanted with SCC VII Tumor
Ryo Akima, Yasuhiro Ogawa, Shiho Morita-Tokuhiro, Akira Tsuzuki, Shin Yaogawa, Shinji Kariya, Norihiko Hamada, Akihito Nishioka, Shinichiro Masunaga and Koji Ono
Article Type: Original Article | First Published: March 21, 2016
The therapeutic effect of radiotherapy using linear accelerators (Linac) for relatively large tumors of more than several centimeters in diameter is reduced to one- third due to a large number of hypoxic tumor cells and a significant amount of anti-oxidative enzymes, such as many kinds of peroxidases and catalase. To overcome tumor hypoxia and abundant peroxidase activities, an injection of hydrogen peroxide into tumor tissue is considered to be a most effective method. However, this is consider...
Open Access DOI:10.23937/2378-3419/3/2/1047
P53 Sensitizes Breast Cancer Stem Cells to Let-7 miRNAs Induced Repression
Jian Liu, Ning Du, Huangzhen Wang, Xin Wang, Peili Wang, Jia Zhang, Gang Li, Jing Zhang, Sida Qin, Chongwen Xu, Shou-Ching Tang, Xin Sun, Boxiang Zhang, Dapeng Liu and Hong Ren
Article Type: Original Article | First Published: March 10, 2016
Cancer stem cells (CSCs) are responsible for the tumor recurrence and resistance to chemo-radiotherapy. Let-7 family of miRNAs functions in regulating cancer biology by repressing multiple downstream oncogenes. In this study, we examined the regulatory loop of suppressive let-7 and p53 in the pathogenesis of breast cancer, and explored the mechanism through which this loop affects the growth patterns of breast cancer stem-like cells (BrCSCs)....
Open Access DOI:10.23937/2378-3419/3/2/1046
Metronomic Chemotherapy Preserves Quality of Life Ensuring Efficacy in Elderly Advanced Non Small Cell Lung Cancer Patients
Francesca De Iuliis, Stefania Vendittozzi, Ludovica Taglieri, Gerardo Salerno, Rosina Lanza, and Susanna Scarpa
Article Type: Original Article | First Published: March 01, 2016
Metastatic non small cell lung cancers (NSCLC) are diseases with poor prognosis and platinum-based doublet chemotherapy still remains their standard cure. Elderly patients often present comorbidities that limit the utilization of this chemotherapy; therefore these patients should have a first-line treatment with low toxicity and capable to preserve the quality of life (QoL) but, at the same time, to ensure the best possible response. Furthermore, a first-line treatment allows patients to be fit ...