Open Access DOI:10.23937/2378-3656/1410098
Topical Cream Curadermbec5 Treats a Recalcitrant Basal Cell Carcinoma
Batsev AF, Dobrokhotova VZ and Cham BE
Article Type: Case Report | First Published: March 28, 2016
Solasodine rhamnosides, solamargine and solasonine, are antineoplastics with high affinity, high efficacy and low toxicity as shown in cell culture, animal and human studies. The mode of action is by apoptosis and is accompanied by a high order of specificity. This specificity towards cancer cells is ideal for treating skin cancers. Previous studies show that solasodine rhamnosides in a topical cream formulation CuradermBEC5 is a highly regarded therapy for nonmelanoma skin cancers....
Open Access DOI:10.23937/2377-9004/1410080
Urinary Incontinence as a Presenting Symptom of Bladder Cancer
Elena Vilar Gonzalez, Marta Perez de la Fuente, Enrique Gonzalez Diaz
Article Type: Case Report | First Published: March 25, 2016
Urinary incontinence is a very common complaint among women. We should think of potentially serious aetiologies when there is no response to empiric treatments, especially in postmenopausal women. We report a case of a 69 year old woman, referred to our pelvic floor unit with urinary incontinence and nocturia. After failing with anticholinergic treatment, a transvaginal ultrasound scanning shows an irregular solid lesion of 6 mm, which was diagnosed by further urological investigation as a trans...
Open Access DOI:10.23937/2572-3278.1510011
The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin
Ondrea A. Moore, Ying Gao, Allen Y. Chen, Ross Brittain and Yi Charlie Chen
Article Type: Original Article | First Published: March 22, 2016
The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we present the main extraction methods, anticancer activity and bioavailability of baicalin. Besides, the util...
Open Access DOI:10.23937/2572-3243.1510008
Bone Mineral Density Measured by Quantitative Computed Tomography in pre-pubertal/Early Pubertal children with hypovitaminosis D
Ferenc Peter, Agota Muzsnai, Laszlo Blatniczky and Peter Lakatos
Article Type: Original Article | First Published: March 28, 2016
These examinations were performed in pre-pubertal and early pubertal white European children living in one of the inner Buda districts of Budapest. This region of the city is populated by slightly more well-to-do families than the average. The selection was made in two schools. All parents of studied children provided written informed consent, enrollment included more than 90% of children in the chosen classes. To avoid the effects of pubertal changes as far as possible, the upper age-limit was ...
Open Access DOI:10.23937/2474-3658/1510010
Prevalence of β-Lactamase Positive Ampicillin Resistant H. Influenzae from Children of Bangladesh
Harunur Rashid, Shereen Shoma and Mahbubur Rahman
Article Type: Original Article | First Published: March 26, 2016
A total of 255 NPS specimens were collected from every seventh of 1786 children with meningitis (n = 293) and pneumonia (n = 1493). One hundred and twenty one (47.5%) H. influenzae were isolated from 255 NPS specimens. Among 121 isolates, 15 (38%) were recovered from meningitis compared to 106 (49%) from pneumonia cases (P < 0.3). Fifteen percent of isolates (18/121) were serotype b (Hib) and the rest were non-Hib....
Open Access DOI:10.23937/2572-3235.1510013
Adaptive Radiotherapy for Limited Stage Small Cell Lung Cancer
Lindsay Rowe, Andra Krauze, John Hanson and Don Yee
Article Type: Research Article | First Published: April 13, 2016
The addition of thoracic RT to chemotherapy for limited stage small cell lung cancer (LS-SCLC) patients provides improved local control and overall survival. Despite the improved outcomes provided by thoracic RT, LS-SCLC has a high local recurrence rate and low survival after contemporary treatments. Local control rates remain 47% at 2-years, and 5-year overall survival remains 5-10%....