Open Access DOI:10.23937/2474-3674/1510018

Aetiology and Presentation of Intestinal Obstruction among Patients Presenting to a Tertiary Hospital in Uganda

Arlene Muzira Nakanwagi, Stephen C Kijjambu, Peter Ongom and Tonny Stone Luggya

Article Type: Research Article | First Published: July 04, 2016

Intestinal Obstruction is the impairment of normal flow of intestinal contents from mouth to anal canal with aetiology that varies depending on various factors. Understanding aetiology of a country's surgical services has proven to aid better planning for its emergency surgical conditions. Mulago, which is Uganda's National Referral Hospital, is resource constrained with a surgical burden of 33% due to acute abdomen with Intestinal Obstruction. This study aimed to determine the current presentat...

 Open Access DOI:10.23937/2474-3674/1510017

Arginine in the Critically Ill: Can we Finally Push Past the Controversy?

Martin D Rosenthal, Cameron Rosenthal, Jayshil Patel, Janeen Jordan, Kristina Go and Frederick A Moore

Article Type: Review Article | First Published: July 04, 2016

Arginine is a conditional amino acid that has a wide breadth of metabolic activity and applications when supplemented. During critical illness, high stressed states, and increased metabolic demand arginine becomes an essential amino acid. It is during this time that supplementation benefits the host. Arginine supplementation during sepsis, however, has remained controversial as there is theoretical harm stemming from arginine serving as a substrate for nitric oxide production. In this review we ...

 Open Access DOI:10.23937/2378-3672/1410018

Uridine Cytidine Kinase Like-1 Enhances Tumor Cell Proliferation and Mediates Protection from Natural Killer-Mediated Killing

Gail Gullickson, Elise C. Ambrose, Richard G. Hoover and Jacki Kornbluth

Article Type: Original Research Article | First Published: May 24, 2016

Uridine cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein over-expressed in many tumor cells, especially in highly malignant, aggressive tumors. Sequence analysis indicates that UCKL-1 has homology to uridine kinases, enzymes that play a role in DNA and RNA synthesis and that are often up-regulated in tumor cells. Previous studies have shown that UCKL-1 is a substrate for natural killer lytic-associated molecule (NKLAM), an E3 ubiquitin ligase found in NK cell cytolytic granul...

 Open Access DOI:10.23937/2377-4630/3/2/1047

Comparison of the Analgesic Effects of Preemptive Lornoxicam and Paracetamol after Laparoscopic Cholecystectomy

Tugba Karaman, Tamer Kuzucuoglu, Gulten Arslan, Serkan Karaman and Mujge Hatun

Article Type: Original Article | First Published: June 13, 2016

Despite increasing knowledge about pain, postoperative pain management is still a challenge. Opioids are widely used drugs in the treatment, but the side effects of the opioids lead to investigations about the novel pain management strategies. We aimed to compare the effects of preemptive intravenous lornoxicam and paracetamol on postoperative pain scores, opioid consumption, and patient satisfaction during laparoscopic cholecystectomy recovery....

 Open Access DOI:10.23937/2378-3656/1410109

The Biliary Sinus: A Rare Late-Stage Complication of Cholecystectomy

Ihsan Yildiz, Yavuz Savas Koca and Ibrahim Barut

Article Type: Case Report | First Published: June 03, 2016

A 53-year-old female patient who had undergone open cholecystectomy due to cholelithiasis 6 years earlier was admitted to hepatobiliary surgery unit with a painful mass in the right upper quadrant and fever. Ultrasonography showed that a 3-cm fluid-filled mass in the right upper quadrant subcutaneously, in computed tomography a fluid-filled tubular lesion extending from the right lobe of liver to right upper quadrant, and percutaneous cholangiography showed that a radio-opaque density communicat...

 Open Access DOI:10.23937/2378-3656/1410108

Left Atrial Appendage Occluder with Recurrent Thrombus Formation Visualized by Three-Dimensional Transesophageal Echocardiography

Sebastian Greiner and Hugo A Katus

Article Type: Case Report | First Published: May 31, 2016

A 78-year-old Caucasian female with newly diagnosed atrial fibrillation was put on anticoagulation with phenprocoumon. Two months later she developed an intracranial hemorrhage localized in the brainstem. Neurological findings were paresis and paraesthesia of the left body side. The treatment was conservative and symptoms resolved within three months....

 Open Access DOI:10.23937/2378-3656/1410107

Chemotherapeutic Agents for Brain Metastases in Non-Small Cell Lung Cancer: A Case Report with Eribulin Mesylate and Review of the Literature

Alejandra C Fuentes, Reordan O De Jesus and David N Reisman

Article Type: Case Report | First Published: May 30, 2016

Lung cancer accounts for the majority of cases of brain metastases, resulting in higher morbidity and mortality. Surgery and radiation are the current standard of care for the treatment of brain metastases. However, when brain metastases recur despite these treatments, the management options are limited, especially when recurrent metastatic events occur. The role of systemic chemotherapy for brain metastases remains undefined, with advances in drug delivery and ongoing studies using targeted age...

 Open Access DOI:10.23937/2572-4037.1510012

Psychological Progress in Schizophrenic Patients undergoing Psychoanalytic Psychotherapy

Gillian Steggles

Article Type: Review Article | First Published: May 18, 2016

Psychoanalytic psychotherapy uses psychoanalytic principles in delivering psychotherapy which supports patients as well as informing them about themselves and the external world through psychoanalytic interpretations. Undergoing a psychoanalysis can be very stressful, and requires ego strength that allows assimilation of personal knowledge by the patient and its utilization within the personality. Classical psychoanalysis makes heavy demands on the analysand's, or patient's, stamina, and schizop...

 Open Access DOI:10.23937/2572-4037.1510011

Psychometric Properties of the Swedish Version of the Personality Inventory NEO-PI-3

Hakan Kallmen, Peter Wennnberg, Per Andreasson and Hans Bergman

Article Type: Short Communication | First Published: March 30, 2016

Background: The NEO-PI and its successors (NEO-PI-R and the latest NEO-PI-3) are among the most commonly used instruments to assess personality internationally. The American version of NEO-PI-3 is adapted to modern language and is more readable than its predecessors. Aims: The present study describes the development of the Swedish version of the NEO-PI-3 and its psychometric properties. Methods: A web-based questionnaire was sent to a random sample from the Swedish population and 18.5% responded...

 Open Access DOI:10.23937/2378-346X/1410057

Orbital Contracture Repair Using the Radial Forearm Free Flap: A Nine and Ten Year Follow-up

Brian T Andrews, Russell B Smith, Todd E Thurston and Keith D Carter

Article Type: Case Series | First Published: June 01, 2016

Introduction: Orbital contracture is a severe cicatricial process within the enucleated orbit prohibiting the use of an ocular prosthesis and often requires socket expansion procedures. We hypothesize that the RFFF provides stable long-term expansion of the contracted orbit and allows for continued ocular prosthesis use without the accumulation of keratin debris. Methods: A retrospective chart review was performed at the University of Iowa Hospitals and Clinics....