Open Access DOI:10.23937/2572-3243.1510017
Developmental Insights into Osteoarthritis Increase the Applicability of New Animal Models
Brunt LH, Kague E and Hammond CL
Article Type: Review Article | First Published: July 14, 2016
Osteoarthritis (OA) is an increasingly common degenerative joint condition, estimated to affect more than 100 million people worldwide and more than 40% of people over 70 years of age. There is currently no pharmacological cure. The genetic contribution to osteoarthritis is estimated at between 39 and 60% in knee and hip OA respectively and a number of Genome Wide association studies have identified a number of alleles and loci that confer increased susceptibility to OA....
Open Access DOI:10.23937/2572-3243.1510015
Perspectives on Improving the Efficacy of PRP Treatment for Tendinopathy
James H-C Wang and Xavier Nirmala
Article Type: Commentary | First Published: June 30, 2016
Platelet-rich plasma (PRP), popularly called PRP, is almost like a "house-hold" name these days because of its wide recognition by physicians and patients due to its prevalent use. The popularity of PRP is due to its efficacy in treating chronic tendon injury (or tendinopathy) in some clinical studies. It is particularly preferred by elite athletes because PRP injections were reported to accelerate healing and enable quicker return to sport activities....
Open Access DOI:10.23937/2572-3308.1510019
An Investigation of the Occurrence of Atopic Dermatitis in Khomas Region School Children, Windhoek, Namibia
Rauna Fanuel Kandowishi, Munyaradzi Mukesi, Sylvester Rodgers Moyo and Kang Erxun
Article Type: Research Article | First Published: August 02, 2016
The aetiology of atopic dermatitis remains poorly understood in Namibia despite considerable research in other developing and developed countries. Although there is growing knowledge about factors that may predispose to the onset of atopic dermatitis (AD), as well as factors which may exacerbate existing disease among school children in Namibia very little is known about the epidemiology of atopic dermatitis (AD), and studies from Southern Africa and Namibia in particular are limited. The resear...
Open Access DOI:10.23937/2469-5696/1410022
First Haploidentical Transplant in Peru in Pediatric Patient with Bilineal Leukemia
Mariela Del Carmen Moreno, Cinthia Palacios and Yessenia Cruz
Article Type: Case Report | First Published: August 01, 2016
Bilineal leukemia is a very rare health condition, especially in pediatric patients; it is associated with poor prognosis, even without uniformity therapeutic criteria. Hereby, we present a 4-year-old boy, who debuted as T-cell lymphoblastic lymphoma, he initially received treatment induction, which was unanswered, further studies showed evidence of being bilinear leukemia (T-AML M5). He continued the AML induction therapy followed by four consolidations, achieving CR....
Open Access DOI:10.23937/2378-3656/1410119
Bilateral Clavicle Fracture: A Rare Presentation of a Common Form of Orthopedic Birth Injury
Joana Oliveira, Andreia Abrantes, Raque Gouveia and Graca Oliveira
Article Type: Case Report | First Published: July 14, 2016
A female newborn presented at day-1 with isolated right clavicle crepitus after vaginal delivery by certified nurse midwives. Shoulder dystocia was suspected at birth but delivery was successful with the sole aid of suprapubic pressure. The adequate weight-for-gestational-age female newborn (3605 gr. at 39 Wk.) was vigorous at birth and no resuscitation was needed. Bilateral clavicle fracture was later confirmed by radiographic studies and associated birth injuries like brachial plexus paralysis...
Open Access DOI:10.23937/2378-3656/1410118
Pulmonary Alveolar Hemorrhage While on Dual Antiplatelet Therapy
Brian Grondahl
Article Type: Case Report | First Published: July 11, 2016
Prasugrel is an anti-platelet agent in the thienopyridine class of adenosine diphosphate receptor inhibitors. It is commonly used in combination with low-dose aspirin as dual antiplatelet therapy (DAPT) in patients who have undergone percutaneous coronary intervention with stent placement. Prasugrel's use is associated with an overall low risk of bleeding (2.4% risk of major hemorrhage), but is avoided in the elderly and those with a low body mass index....
Open Access DOI:10.23937/2469-5823/1510052
Undergraduate Nursing Students' Perceptions of High-Fidelity Simulation-Based Learning
Yueh-Chen Yeh
Article Type: Review Article | First Published: June 27, 2016
Because of the growing expectations for novice nurses to be adequately prepared to work in complex healthcare settings, pressure has dramatically increased for nursing schools to deliver better training. Nurse educators must explore innovative teaching methods to link the gap between knowledge and practice in order to enhance the students' ability to function as competent nurses. Researchers stated that simulation has the potential to help nurse educators better train students, especially when f...
Open Access DOI:10.23937/2469-5823/1510051
Communication and Effective Interprofessional Health Care Teams
Gary L Kreps
Article Type: Review Article | First Published: June 27, 2016
It is increasingly important for health care professionals and consumers to participate actively and competently in interprofessional health care teams to contribute specialized knowledge and skills toward addressing complex health care challenges. However, team members must be sensitized to the communication demands of working effectively in health care teams....
Open Access DOI:10.23937/2469-5823/1510050
Why is Respiratory Rate the Neglected Vital Sign? A Narrative Review
Malcolm Elliott
Article Type: Review Article | First Published: June 26, 2016
Respiratory rate assessment is essential for detecting acute changes in a patient's condition. Despite this, research has shown that it is the most neglected vital sign in clinical practice. This literature review identified three key reasons for this: inadequate knowledge regarding respiratory rate assessment; nurses' perception of patient acuity; and lack of time. These factors suggest poor understanding of the importance of respiratory rate as a vital sign....