Open Access DOI:10.23937/2469-5750/1510031
Fluoroscopy-Induced Chronic Radiodermatitis
Tugba Falay, Vefa Asli Erdemir, Sevil Savas, Mehmet Salih Gurel and Ezgi Ozkur
Article Type: Case Report | First Published: August 29, 2016
Fluoroscopy induced chronic radiation dermatitis (FICRD) is a rare complication which can be difficult to diagnose and treat. Recently fluoroscopy use has increased and the diagnostic and the theuropathic fluoroscopy procedures are becoming more complex; therefore incidence of FICRD is rising. Because of presentation often occurs after months or years patients are sometimes unaware of exposure to radiation....
Open Access DOI:10.23937/2469-5807/1510044
Clinicopathological Study of Angiogenesis in Gastric Cancer
Evangeli S Lampri, Anna C Goussia and Niki J Agnantis
Article Type: Review Article | First Published: August 31, 2016
Many models of multistage tumorigenesis have been proposed to explain the conversion of a normal cell into a neoplastic one. In addition to all genetic and epigenetic changes, angiogenesis is necessary for the growth and expansion of tumors. Besides, no neoplastic lesion could not exceed the size of 2 mm if not supported by a rich vascular network....
Open Access DOI:10.23937/2469-5807/1510043
A Review of Carcinoma Ex-Pleomorphic Adenoma of the Salivary Glands
Saeedeh Khalesi
Article Type: Review Article | First Published: August 31, 2016
One of the malignant forms of pleomorphic adenomas (PA) is carcinoma ex pleomorphic adenoma (CA-ex-PA). Carcinoma ex pleomorphic adenoma is an uncommon malignant tumor with high aggressive behavior and poor prognosis. However, there are a few studies in this topic in the recent literature. Furthermore, the lesions are uncommon and often have a difficult diagnosis by clinicians and pathologists, because the residual small PA component and various malignancy subtypes may be present. In this study,...
Open Access DOI:10.23937/2469-5807/1510042
Basaloid Salivary Gland-Analogue Tumors of the Mammary Gland: Clinicopathologic Assessment of a Rare Subtype
Andrew L Walls, Lavinia P Middleton, Adel K El-Naggar and Aysegul A Sahin
Article Type: Review Article | First Published: July 31, 2016
Salivary and mammary glands share common ontology, but variable prevalence of tumor subtype frequency. Common primary salivary gland-type tumors are rare and less recognized in breast. Analogous to primary basaloid salivary tumors, basaloid mammary carcinomas, as in primary salivary, exhibit a spectrum of features from benign to malignant. The rarity and unfamiliarity of these tumors may lead to diagnostic and management challenges....
Open Access DOI:10.23937/2378-3648/1410028
Generation of Epstein-Barr Virus Immortalized-B Lymphocytes Cell Line of Orang Asli
Mohd Helmy Yusof, Sharifah Izwan Tuan Othman, Siti Shuhada Mokhtar, Yushimah Yunus, Abu Thalhah Abdul Aziz and Hoh Boon Peng
Article Type: Original Article | First Published: September 26, 2016
Obtaining sustainable source of cells or DNA from a single individual has always been a constraint in biomedical research. Generation of lymphoblastoid cell lines (LCLs) as a surrogate for replacement of isolated peripheral blood mononuclear cells (PBMCs) has substantially accelerated the process of biological investigations. LCLs can be established by transfection of B lymphocytes from peripheral blood with Epstein Barr Virus (EBV), bearing minor genetic and phenotypic alterations....
Open Access DOI:10.23937/2378-3648/1410027
An Overview on the Phylogeny of Aerobic Metabolism and the Preponderance of Mitochondrial Functions in Evolution
Denis Rousseau
Article Type: Review Article | First Published: September 15, 2016
Aerobic oxidation of carbohydrates by mitochondria has been a great invention of nature, marking a big step in early evolution. This biological system has greatly multiplied the energy production of the cell by supplying this energy to different metabolic units, with increased temporal and spatial specificities. The numerous mitochondrial functions that have emerged and developed along evolution constitute strong signatures of evolution pressures, driving toward higher order, more complex and mo...
Open Access DOI:10.23937/2469-5793/1510043
Improving Conceptual Clarity of Antenatal Interventions: A Scoping Review
Melissa Buultjens, Gregory Murphy, Jeannette Milgrom and Darren Poinen
Article Type: Review Article | First Published: September 02, 2016
There is increasing awareness of perinatal health as a public health issue, while the antenatal period is a transitional time for parents-to-be and presents various opportunities to maximize health outcomes. The objectives of this scoping review were to identify non-pharmacological interventions in antenatal care, to examine the health outcomes and reductions of perinatal morbidity occurring in childbearing women as a result of these interventions, to explore the mechanisms of intervention effec...
Open Access DOI:10.23937/2469-5793/1510042
Implementation and Outcomes of a Community-Based Educational Program for Colorectal Cancer Prevention in Hispanics
Marcia Cruz-Correa, Frances Cordero, Jean Pierre Betancourt, Yaritza Diaz-Algorri, Sofia M. Lopez, Mirza Rivera, Rafael Mosquera, Victor Carlo-Chevere and Segundo Rodriguez-Quilichini
Article Type: Original Article | First Published: August 25, 2016
The TTT program consisted of didactics and seminars to capacitate participants to become trainers in CRC prevention. This project was evaluated using three components: (1) training workshops; (2) community educational sessions; and (3) the participant's experience as a trainer. Pre - and post-tests on CRC screening knowledge were given to TTT participants. Program effectiveness was determined by the pre- and post-tests, number of workshop participants completing a community educational session w...
Open Access DOI:10.23937/2469-5793/1510041
Attitudes to Changes in Cervical Screening Guidelines: Preliminary Views of Australian General Practitioners and Nurse Practitioners
Olivia Denham, Suzanne M Garland, Alexandra Gorelik, Gina Ogilvie, Jeffrey Tan, Danielle Mazza, C David H Wrede, Barbara McBride and Yasmin Jayasinghe
Article Type: Research Article | First Published: August 22, 2016
GPs and nurse practitioners were invited to complete an online survey through advertisements in e-newsletters. The survey assessed participants' demographics, cervical screening practices and perceived barriers to screening according to the proposed new guidelines. Responses were on a 7-point Likert scale. Statistical analysis was performed using the chi-square for categorical variables and student T-test for continuous variables. Adjusted odds ratios were determined using multivariate logistic ...