Open Access DOI:10.23937/2469-567X/1510028

Successful Treatment of Chronic Hepatitis C using Pegylated Interferon and Ribavirin in a Patient with Sheehan's Syndrome

Rong Xu, Yong-hong Zhang and Xu Yang

Article Type: Case Report | Publication Updated: September 29, 2016

A 50-year-old female with Sheehan's syndrome was treated for chronic hepatitis C using pegylated interferon-α2b and ribavirin. The patient's HCV-RNA status was negative by the fourth week and remained undetectable until the completion of treatment without signs that Sheehan's syndrome had been exaggerated. This case demonstrates that pegylated interferon-α2b and ribavirin does not necessarily exacerbate Sheehan's syndrome....

 Open Access DOI:10.23937/2469-567X/1510027

Human Immunodeficiency Virus Infections in the Middle East and North Africa: Prevalence, Risk, Prevention and Challenges

Ahmed A Abd-Rabou

Article Type: Review Article | Publication Updated: September 27, 2016

The Middle East and North Africa (MENA) has few recorded outputs regarding the prevalence of the human immunodeficiency viral (HIV) infections associated with acquired immune deficiency syndrome (AIDS). When we went through the HIV/AIDS in MENA, we found a hole in the scientific publications. Attention towards this issue progressed recently though, with few pre-clinical studies conducted. In the current review, we collected comprehensive data of HIV epidemiology in MENA and discussed the main ch...

 Open Access DOI:10.23937/2469-5793/1510046

Screening for Urethral, Rectal and Pharyngeal Gonorrhea & Chlamydia among Asymptomatic Male Adolescents and Young Men who have Sex with Men

Faiza Ali, Gaurav N Kaushik, Nicole D Carr, Ericka Hayes and Katie L Plax

Article Type: Original Article | Publication Updated: November 08, 2016

Urban young men (13-25 years old) who have sex with men (YMSM) are at high risk for sexually transmitted infections (STIs). Centers for Disease Control and Prevention (CDC) recommendations are to screen asymptomatic MSM for Chlamydia trachomatis (CT) and Neiserria gonorrheae (GC) based on sexual history. However, this approach misses asymptomatic non-genital infections in men who do not disclose or are not asked about sexual behavior. Our study aimed to determine prevalence of asymptomatic phary...

 Open Access DOI:10.23937/2469-5793/1510045

Real-Data Comparison of Data Mining Methods in Early Detection of Chronic Obstructive Pulmonary Disease (COPD) in General Practice

Rodriguez-Alvarez Cristobalina, Ruperez Felix, Gonzalez-Davila Enrique, Gonzalez-Martin Isidro, Castro Beatrizand and Arias Angeles

Article Type: Original Research | Publication Updated: November 07, 2016

Health authorities have increased the attention given to chronic obstructive pulmonary disease (COPD) in recent years. Even so, under-diagnosis and late diagnosis rates remain high. The aim of this study was to determine which factors allow to discriminate between people with COPD and which do not, trying to provide a simple tool that can be used by primary health care personnel....

 Open Access DOI:10.23937/2469-5793/1510044

Prolonged Esophageal Button Battery Impaction in a 15 Month-Old: A Case Report

Jennifer Marshalla and Kelly Williamson

Article Type: Case Report | Publication Updated: September 13, 2016

A 15 month-old female was transferred to the emergency department from a gastroenterologist's office after a chest x-ray revealed an esophageal foreign body. The patient was undergoing evaluation for regurgitation of food and refusal to eat solid food for three months with their primary care physician. X-ray of the neck upon arrival in the emergency department revealed that the foreign body was consistent with a button battery. The button battery was likely lodged in the esophagus for the three ...

 Open Access DOI:10.23937/2378-3397/1410048

Markedly Elevated Tumor Markers with a Benign Epidermoid Cyst of Spleen

Jane Lee, Jingjing Sherman and L Brian Katz

Article Type: Case Report | Publication Updated: October 17, 2016

A 25-year old female presented with left upper quadrant pain of several weeks duration. Her labs were significant for elevated tumor markers including CA 19-9, CA 125 and CEA. Computed tomography of the abdomen showed ascites, ovarian cysts and enlarged spleen with a large cystic lesion measuring approximately 9.9 × 3.2 cm. Diagnostic laparoscopy revealed an enlarged cystic spleen, ovarian cysts and no evidence of malignancy. Splenectomy was performed along with ascites cytology, peritoneal...

 Open Access DOI:10.23937/2378-3397/1410047

Surgical Gastrostomy in Delayed Emergency: Indications, Morbidity and Mortality in 293 Patients from a Single Center Experience

Anne-Sophie Studer, Vincent Venchiarutti, Edouard Girard, Jessica Morel, Julio Abba and Catherine Arvieux

Article Type: Original Article | Publication Updated: October 15, 2016

293 patients under went surgical gastrostomy according to the Witzel technique. Age, gender, indication, type of anesthesia, complications and 30-days mortality were analyzed. Complications were detailed according to type minor (tube site infection, gastric tube removal, obstruction, breakage or leakage, intra-abdominal displacement, parietal hematoma) or major (gastric bleeding, aspiration pneumonia, gastroesophageal reflux, peristomal hernia, peritonitis, digestive perforation, incisional hern...

 Open Access DOI:10.23937/2469-5807/1510048

A Battle against the Odds: Intensive Therapy in Thrombotic Storm

Priyanka Raheja, Pavel Olivera, Veronica Pons, Mercedes Perez, Joan Balcells, Romy Rossich and Amparo Santamaria

Article Type: Case Report | Publication Updated: October 31, 2016

Thrombotic storm (TS) is a rare life-threatening entity that is characterized by multiple thrombotic events affecting diverse vascular sites occurring over a short period of time (days to weeks). We describe a case of a young boy who developed extensive and rapidly progressive thrombosis which required intensive treatment that included the use of triple antithrombotic therapy, pharmacomechanical thrombectomy, systemic thrombolytic therapy, and the combined use of plasmapheresis and immunosuppres...

 Open Access DOI:10.23937/2469-5734/1510034

Case Report: Ultraconservative Cad/Cam Ceramic Restorations for the Treatment of Developmental Enamel Defects

Pita A, Dimosiari G, Marinou G and Tsitrou E

Article Type: Case Report | Publication Updated: November 03, 2016

Developmental enamel defects can cause a number of problems to patients. Tooth sensitivity, loss of aesthetics and functionality of the involved teeth are some of the many problems reported by patients. This clinical report aims to present a treatment modality for developmental enamel defects following a very conservative approach to restore functionality and aesthetics....

 Open Access DOI:10.23937/2469-5734/1510033

Medication-Related Osteonecrosis of the Jaw with the mTOR Inhibitor Everolimus in a Patient with Estrogen-Receptor Positive Breast Cancer: A Case Report

Cameron YS Lee, Kristin L Lee, Kirk Y Hirata and Jon B Suzuki

Article Type: Case Report | Publication Updated: September 17, 2016

In the treatment of bone metastases from breast cancer, bisphosphonates are considered the cornerstone of treatment to prevent adverse skeletal related events. Intravenous bisphosphonates reduce bone resorption by inhibiting osteoclast function. However, osteonecrosis of the jaws is a commonly reported side effect with intravenous bisphosphonates to treat malignancies, such as breast cancer and restricts their clinic use. New targeted therapies have recently been introduced to improve progressio...