Open Access DOI:10.23937/2474-1353/1510052

Reversible Posterior Encephalopathy Syndrome in Patient with Acute Intermittent Porphyrin: A Case Report

Ya Duan, Shan Kang, Jian Zhao and Zengjun Tang

Article Type: Case Report | First Published: May 24, 2017

Acute Intermittent Porphyria (AIP) is a metabolic disease caused by an inherited deficiency of heme biosynthesis. Acute attacks of AIP during pregnancy are very rare. However, it presents the obstetrician with challenging problems. Prompt diagnosis and early detection of the disease are crucial for the appropriate treatment and favorable prognosis....

 Open Access DOI:10.23937/2469-584X/1510045

Giant Hiatus Hernia and Association with Gastro-Oesophageal Reflux: A Review

Kevin J Chan, Bernard M Smithers and Michael W Hii

Article Type: Review Article | First Published: May 31, 2017

A Hiatus Hernia (HH) describes the protrusion of intra-abdominal contents, through the oesophageal hiatus of the diaphragm and into the mediastinum. The hernia typically contains the stomach to varying degrees but may include other organs such as the omentum, colon, liver, pancreas and spleen....

 Open Access DOI:10.23937/2469-584X/1510044

Effect of EGF on Bax, Bcl-2 and Fas Expression in Ulcerous Disease and N87 Cell Line

Fatma Soylemez, Ozlem Izci Ay, Ertan Ay, Engin Altintas, Cagatay H Turkseven and Mehmet E Erdal

Article Type: Research Article | First Published: May 15, 2017

To evaluate the effect of EGF in primary culture of ulcer patients and N87 cell line on expressions of apoptotic genes. Ulcer patients who applied to Gastroenterology Clinic of Mersin University Medical Faculty were included in this study. EGF application to the primary culture of biopsy samples with ulcer patients and gastric cancer cell-line (ATCC-NCI-N87) has been carried out at three different doses....

 Open Access DOI:10.23937/2572-3243.1510035

Minimally Invasive Percutaneous Screw Fixation of Phalangeal Fractures of the Hand

Simon-Perez C, Garcia-Virto V, Garcia-Medrano B, Rodriguez-Mateos JI, Faour-Martin O and Martin-Ferrero MA

Article Type: Research Article | First Published: June 01, 2017

This study present the results of an effective, minimally invasive treatment method for displaced diaphyseal and articular fractures of hand phalanges, which are difficult to manage and frequently involve complications stemming from excessive treatment....

 Open Access DOI:10.23937/2572-3243.1510034

Acute Lymphoblastic Leukemia in Systemic Lupus Erythematosus Disguise: A Case Report

Gaafar Ragab, Hala El-Gendy and Rasmia M El-Gohary

Article Type: Case Report | First Published: June 08, 2017

The present report describes the case of an 18-year-old male exhibiting Acute Lymphocytic Leukemia (ALL). He initially presented with a multitude of rheumatic manifestations that were attributed to Systemic Lupus Erythematosus (SLE). The initial peripheral smear and bone marrow exam did not show any abnormal cells that developed later on along his disease course....

 Open Access DOI:10.23937/2469-5742/1510027

Managing the Elderly with Urinary Incontinence and Dementia

Si Ching LIM

Article Type: Research Article | First Published: June 05, 2017

The elderly patients with dementia are often challenging to manage, especially if they have urinary incontinence. There are many causes for urinary incontinence and among the elderly with dementia, the problem is often not related to abnormalities of the lower urinary tract....

 Open Access DOI:10.23937/2469-5742/1510026

Impact of Pneumoperitoneum on the Post-Operative Renal Function and Level of Acute Kidney Injury Markers: Comparison between Laparoscopic and Open Nephrectomy

Amjad Shalabi, Omri Nativ, Mustafa Sumri, Bishara Bishara, Wisam Khoury, Hoda Awad, Ofer Nativ and Zaid Abassi

Article Type: Research Article | First Published: May 24, 2017

As laparoscopic surgery becomes more widespread, understanding the adverse effects of pneumoperitoneum becomes more important, especially in patients subjected to laparoscopic unilateral nephrectomy. The purpose of the current study was to investigate the effect of pneumoperitoneum on the remnant kidney after laparoscopic nephrectomy compared to open surgery....

 Open Access DOI:10.23937/2469-5742/1510025

Orchitis the Strange, the Rare and the Unusual: Case Report and Review of the Literature

Pace Gianna, Benzone Stefano and Pola Lisa

Article Type: Review Article | First Published: March 07, 2017

Orchitis are classified as granulomatous and non-granulomatous orchitis. Several agents are responsible for inflammatory and infective diseases of the testis, causing orchitis. The most common clinical features are scrotal swelling, mass and/or pain. The diagnosis is mainly histological because clinical and sonographic aspects may be not conclusive....

 Open Access DOI:10.23937/2378-3648/1410030

Thermo Stability of DNA Methylation Marks in Human Sperm

Timothy G Jenkins, Monis B Shamsi, Emma James, Kenneth I Aston and Douglas T Carrell

Article Type: Research Article | First Published: June 12, 2017

Shipping of various tissues, including sperm, for the purposes of diagnostic testing and/or collaborative scientific pursuits is commonly performed. While many sample attributes are largely stable during the shipping process regardless of shipping environment, some physical factors such as temperature, duration of storage and other handling conditions may affect certain features of these samples including a commonly assessed epigenetic mark, DNA methylation....

 Open Access DOI:10.23937/2378-3648/1410029

Testing the Mutagenicity Potential of Chemicals

Geert R Verheyen, Koen Van Deun and Sabine Van Miert

Article Type: Research Article | First Published: May 15, 2017

All information for the proper development, functioning and reproduction of organisms is coded in the sequence of matched base-pairs of DNA. DNA mutations can result in harmful effects and play a role in genetic disorders and cancer. As mutations can arise through exposure to chemical substances, testing needs to be done on substances that humans and animals can be exposed to....