Open Access DOI:10.23937/2469-584X/1510047

A Case of Serial Liver Injury Induced by Plant Food Supplements in a Young Healthy Man

Gianluca Cappelleri, Enrico Sangiovanni and Mario Dell'Agli

Article Type: Case Study | First Published: July 08, 2017

The use of botanicals is increasingly throughout the world. They are ingredients of different types of products, such as herbal medicinal products, Plant Food Supplements (PFS), and functional foods. They are commonly taken to promote health and treat or prevent diseases, even if, in most of cases, there is no clear evidence of their clinical efficacy....

 Open Access DOI:10.23937/2469-584X/1510046

Pediatric Ulcerative Colitis from Prevalence to Outcome

Hasan M Isa, Afaf M Mohamed, Halima E Al-Jowder and Khadija A Matrook

Article Type: Research Article | First Published: June 30, 2017

Pediatric Ulcerative Colitis (UC) is an Inflammatory Bowel Disease (IBD) that has potential morbidities, lifelong challenges and can leave both physical and psychosocial impacts. This study aimed to review the epidemiology, clinical presentations, and way of diagnosis, therapeutic approaches, complications and outcome of pediatric patients with UC....

 Open Access DOI:10.23937/2469-567X/1510030

Sensitive, Subtype Independent HIV-1 PCR Assays for Assessment of Residual Viremia and Total HIV-1 DNA

Tomas Mellberg, Jon Krabbe, Maria J Buzon, Ulrika Noborg, Magnus Lindh, Staffan Nilsson, Bo Svennerholm and Magnus Gisslen

Article Type: Original Research | First Published: July 01, 2017

Correct measurements of residual viremia and reservoir size are crucial in HIV-1 eradication trials and there is a need for sensitive and automated assays. The increasing worldwide diversity of HIV-1 subtypes stresses the importance of subtype independent assays....

 Open Access DOI:10.23937/2469-567X/1510029

Virologic Response and Survival Analysis of 281 HbsAg Treatment Naive Patients on Lamivudine Monotherapy in Sierra Leone

Jia B Kangbai, Isata Victoria Mandoh and Peter Bai James

Article Type: Research Article | First Published: June 17, 2017

More than 350 million people are infected with Hepatitis B Virus (HBV) globally. The main aim of any chronic hepatitis B therapy is to prevent liver cirrhosis and its sequelae, including Hepatocellular Carcinoma (HCC)....

 Open Access DOI:10.23937/2572-4053.1510015

Polycystic Ovarian Syndrome and Narcolepsy: A Coincidental Relationship?

Danielle Lee, Bishoy Kolta and Karim Sedky

Article Type: Case Report | First Published: June 28, 2017

A relationship between Polycystic Ovarian Syndrome (PCOS) and narcolepsy have not been well examined. Both disorders share common co morbidities including obesity, Obstructive Sleep Apnea (OSA), and Excessive Daytime Sleepiness (EDS). ...

 Open Access DOI:10.23937/2469-5750/1510046

Paraneoplastic Pemphigus

Zhong-Shuai Wang and Jun Li

Article Type: Review Article | First Published: July 08, 2017

Paraneoplastic Pemphigus (PNP) is an autoimmune-related acquired bullous disease associated with neoplasia. Both humoral and cellular immunity are involved in the pathogenesis of PNP. Characteristically, PNP has a diverse spectrum of clinical and immunopathological features....

 Open Access DOI:10.23937/2469-5750/1510045

Radiotherapy for Mycosis Fungoides: Review of the Literature

Omer Sager, Hakan Gamsiz, Ferrat Dincoglan, Selcuk Demiral, Bora Uysal and Murat Beyzadeoglu

Article Type: Review Article | First Published: June 12, 2017

Apart from systemic or nodal lymphomas, cutaneous lymphomas present a heterogeneous group of relatively infrequent non-Hodgkin lymphomas with distinct clinical characteristics. Among cutaneous lymphomas, primary cutaneous T cell lymphomas account for the majority of cases with Mycosis Fungoides (MF) being the most prevalent subtype....

 Open Access DOI:10.23937/2572-4061.1510006

Is There any Relationship between Worldwide Pesticide Standard Values in Residential Soil, Drinking Water, and Agricultural Commodity Exposures?

Zijian Li and Aaron A Jennings

Article Type: Research Article | First Published: June 24, 2017

Human could exposure to pesticides via various exposure pathways. Worldwide jurisdictions are making efforts to manage human health risk by regulating pesticide standards in residential soil, drinking water, and agricultural commodity....

 Open Access DOI:10.23937/2572-4061.1510005

Suppression of Calpain-2 by Small Interfering RNA Inhibits Hydrogen Peroxide-Induced Apoptosis in Rat Pancreatic Acinar Cells AR42J

Bettina Hiemer, Alisa Bernert, Frederic LP Gabriel, Michael Wakileh and Heike Weber

Article Type: Research Article | First Published: May 19, 2017

Apoptosis is defined as controlled programmed cell death that occurs as physiological process in the development and morphogenesis of multi-cellular organisms, but is also implicated in various diseases, including acute pancreatitis. Apoptosis can be induced by a wide range of stimuli....

 Open Access DOI:10.23937/2469-5777/1510054

Fixation of a Distal Diaphyseal Tibia Fracture with Neurovascular Tissue Incarceration: Surgical Technique Using a Lesser Invasive Approach

Wilson Belaieff, Dennis Dominguez and Axel Gamulin

Article Type: Case Report | First Published: July 19, 2017

Soft tissue incarceration in a distal diaphyseal tibia fracture may predispose to adverse fracture healing. Incarcerated soft tissue may include nerves and/or vessels, with the potential for neurovascular complications....