Open Access DOI:10.23937/2469-570X/1410050

Autologous Porcine Bone Marrow Mesenchymal Cells for Reconstruction of a Resorbed Alveolar Bone: A Preclinical Model in Mini-Pigs

Cecilie Gudveig Gjerde, Daniele De Santis, Massimo Dominici, Guglielmo Zanotti, Solve Hellem, Serena Piccinno, Jorge S Burns, Alba Murgia, Olivia Candini, Mauro Krampera, Pierfrancesco Nocini, Alessandro Addis, Jerome Amiaud, Pierre Layrolle, Kamal Mustafa and Elena Veronesi

Article Type: Original Research | First Published: November 29, 2017

Regeneration of atrophied alveolar bone prior to insertion of dental implants is a major challenge for oral and maxillofacial surgery....

 Open Access DOI:10.23937/2469-5750/1510051

Usage of Skin Tumor Images on the Internet for Personal Computer Based Automated Cognition

Soh Nishimoto, Yohei Sotsuka, Kenichiro Kawai, Hisako Ishise and Masao Kakibuchi

Article Type: Research Article | First Published: December 02, 2017

Visual diagnosis of skin tumors is one of the most important steps in dealing with them. Nowadays, artificial intelligence has been booming and technology of automated cognition by computer has been improved. One of the bottlenecks in building an efficient cognition system is providing adequate amount of data to base on....

 Open Access DOI:10.23937/2474-3658/1510045

Quality of Perioperative Antibiotic Prophylaxis in a Community Hospital in Western Qatar

H Guanche Garcell, Ariadna Villanueva Arias and RA Nonato Alfonso

Article Type: Original Article | First Published: November 25, 2017

Descriptive study was carried out in a 75-bed public hospital in Western Qatar. The study included the patients underwent selected procedures who required antibiotic prophylaxis from Jan-2013 to June 2016. Data was collected by the infection control practitioner....

 Open Access DOI:10.23937/2572-4193.1510033

Two Cases of Sinonasal Teratocarcinosarcoma: Confounders, Treatment and Review of the Literature

Vidur Bhalla, Naweed Chowdhury, Thomas Muelleman, Sameer Alvi, Chelsea Hamill, Roukoz Chamoun and D David Beahm

Article Type: Case Report | First Published: November 29, 2017

Sinonasal Teratocarcinosarcomas (SNTCS) are rare tumors of the anterior skull base that are typically diagnosed in the fifth decade of life, with only 5 reported cases in children. Treatment typically involves surgical resection and radiotherapy....

 Open Access DOI:10.23937/2469-5858/1510036

Future Demands Concerning the Epigenetic Relevance of Melatonin and the Circadian System in Gerontology

Rudiger Hardeland

Article Type: Review Article | First Published: December 01, 2017

Melatonin is a highly pleiotropic regulator molecule that influences numerous functions in many cell types. Its actions comprise direct and circadian oscillator-mediated effects. The levels of circulating melatonin typically decline in the course of aging....

 Open Access DOI:10.23937/2572-3286.1510033

A Self-Sufficiency Philosophy for Non-Communicable Disease Control

Narisa Futrakul and Prasit Futrakul

Article Type: Communication | First Published: November 25, 2017

A non-communicable disease comprising various vascular diseases namely renal microvascular disease, cerebrovascular disease, and coronary vascular disease, has been a threatening public health problem today. The failure of preventive strategy is due to the lack of understanding the nature of the origin of vascular disease....

 Open Access DOI:10.23937/2469-5769/1510028

Risk Factors for Hospital Readmission and Follow Up after NICU Discharge of Infants Born at Extremely Low Gestational Age in Metropolitan Melbourne

Tejas N Doctor, Efrant Harnaen, Bob Seith, Kenneth Tan and Simon Craig

Article Type: Original Article | First Published: December 04, 2017

Extremely preterm infants, < 28 week of gestational age, (ELGANs) continue to need high levels of health-care post-discharge from the NICU. We studied post-NICU hospital contacts of this highly vulnerable population and present data from infants treated in our health network....

 Open Access DOI:10.23937/2469-5769/1510027

Intravenous Clonidine: A Useful and Safety Sedation for Critically Ill Children

Carme Alejandre, David Vila, David Vila, Sergio Benito, Patricia Corniero, Monica Balaguer, Susana Segura, Francisco Jose Cambra and Iolanda Jordan

Article Type: Research Article | First Published: December 01, 2017

Critically ill children who are admitted to Pediatric Intensive Care Unit (PICU) often receive analgesia and sedation for pain, comfort and safety. Moreover the new objectives of sedation include maintenance of the functioning of the neuromuscular system early upon ventilatory support....

 Open Access DOI:10.23937/2378-3664/1410020

Methotrexate-Loaded PLGA Nanoparticles: Preparation, Characterization and their Cytotoxicity Effect on Human Glioblastoma U87MG Cells

Hassan Maleki, Farid Dorkoosh, Mahdi Adabi, Masood Khosravani, Hossein Arzani and Morteza Kamali

Article Type: Research Article | First Published: November 23, 2017

The purpose of the current study was to prepare Methotrexate (MTX) loaded Poly Lactic-Co-Glycolic Acid (PLGA) Nanoparticles (NPs) and investigates their toxicity effect on human glioblastoma cells. The influence of different experimental parameters including polymer concentration....

 Open Access DOI:10.23937/2469-5866/1510021

The Effect of a Functional Intensive Intervention Program on Self-Care in Children with Cerebral Palsy: A Case Study

Rosanne Roelofsma and Eugene Rameckers

Article Type: Original Research | First Published: November 29, 2017

Former studies have shown that usual care in children with Cerebral Palsy (CP) often lacks effectiveness. Task-oriented functional intensive therapies have been shown to be promising for CP patients. The present case study aimed to examine the effect of a task-oriented functional intensive therapy program....