Open Access DOI:10.23937/2469-5734/1510050

Occlusion: What's behind a Bite? Study of the Knowledge and Attitude about Principles of Occlusion among Dental Professionals

Moksha Nayak and Drisya Soman

Article Type: Research Article | First Published: May 02, 2018

General dental practitioners and non-orthodontic specialists can play an essential role in education and motivation of their patients about the principles and practice of orthodontic treatment; which can be very beneficial to the patient's lifestyle. It is, therefore, important to identify their level of knowledge and attitude toward orthodontic treatment. This study was planned to study this aspect in the form of comparative analysis in general dental practitioners and other specialists includ...

 Open Access DOI:10.23937/2378-3656/1410207

Rhino-Orbito-Cerebral Mucormycosis in Immunocompetent Young Patient: Case Report

Rabab Taha, Talal Almteri, Nizar bahabri and Hani Almoallim

Article Type: Case Report | First Published: March 22, 2018

Mucormycosis is an invasive infection in immunocompromised host. It can lead to a devastating rhino-orbital-cerebral involvement with detrimental consequences. This disease is mainly caused by member of the family Mucoraceae that include Rhizopus, Rhizomucor, Mucor and Lichtheimia (formerly Absdia). This infection classically affects immunocompromised patients. The most common site of this infection in immunocompromised patients related to the pattern of the associated disease. In patients with ...

 Open Access DOI:10.23937/2377-3634/1410086

Cardiovascular Complications and Composition of the Intestinal Microbiome in Patients with Type 2 Diabetes

EG Siegel, J Lorenzo Bermejo, I Flade and C Hasslacher

Article Type: Original Article | First Published: April 28, 2018

Cardiovascular complications (CVCs) are still the most frequent cause of morbidity and death in patients with type 2 diabetes. The current options for the treatment of the classic risk factors such as dyslipoproteinemia, hypertension, and diabetes have so far not been able to alter this situation to a fundamental extent, meaning that new therapeutic approaches must be identified....

 Open Access DOI:10.23937/2469-5726/1510060

Modulation of Histone Deacetylases (HDACs) Expression in Patients with and without Systemic Lupus Erythematosus: Possible Drug Targets for Treatment

Kenneth L Wiley, Edward Treadwell, Kayihura Manigaba, Beverly Word, Jarren Oates and Beverly D Lyn-Cook

Article Type: Research Article | First Published: April 28, 2018

There is increasing evidence that epigenetic factors may play a role in the pathogenesis of Systemic Lupus Erythematosus (SLE). Both global and gene specific methylation is known to occur in lupus patients, as well as, changes in histone acetylation status. Histone acetylation is associated with active chromatin or activation of genes, whereas histone deacetylase (HDAC) activity is associated with silencing of genes. Therefore, HDACs have been targeted as potential therapeutic targets for a numb...

 Open Access DOI:10.23937/2469-5718/1510088

Effects of a Slashpipe Training Intervention on Postural Control Compared to Conventional Barbell Power Fitness

Nicolas Kurpiers, Teresa Rovelli, Christin Bormann and Tim Vogler

Article Type: Research Article | First Published: April 26, 2018

Postural control is essential to maintaining balance and stability under health-related aspects. In the past several training concepts have been recommended for the enhancement of postural control. One of these concepts is the so-called 'Slashpipe' training, which uses a pipe partly filled with liquid in order to complete exercises similar to those found in barbell power fitness programs. However, evidence for the benefits of this intervention is rare. The aim of the study was to investigate the...

 Open Access DOI:10.23937/2469-5718/1510087

The Metabolic Cardio-Respiratory Effects of Abdominal Electrical Muscle Stimulation

Craig E Broeder, Amanda J Salacinski, Steve Mauk and Dimitria Vandarakis

Article Type: Research Article | First Published: April 25, 2018

Electrical Muscle Stimulation (EMS) has been studied in athletes, healthy, and diseased populations mainly focusing on muscle strength and body composition. Therefore, the purpose of this study was to determine the metabolic and cardiovascular effects of acute EMS at rest and steady-state walking (3.5 mph & 5% grade) in healthy adults. Thirty-eight subjects (M = 19, F = 19) volunteered and completed resting and steady-state exercise trials with and without EMS in duplicate on separate days (test...

 Open Access DOI:10.23937/2572-4193.1510035

A Retrospective Study: Good Functional Outcomes are Independent of Pre-Operative Factors in Stapes Surgery for Otosclerosis

Jeremy Goh Chin Guan and Yeo Seng Beng

Article Type: Research Article | First Published: April 28, 2018

Otosclerosis is a disease of the temporal bone that affects the inner and middle ear. It is characterized by a pathological pleomorphic replacement of normal bone with spongiotic or sclerotic bone. Otosclerosis has traditionally been presumptively diagnosed by characteristic clinical findings on medical history, physical examination and audiology testing....

 Open Access DOI:10.23937/2378-346X/1410086

Isolated Ankyloblepharon Filiforme Adnatum in a Newborn

Saroj Gupta and Harsha Saxena

Article Type: Case Report | First Published: April 26, 2018

We report a case of a rare congenital eyelid abnormality, ankyloblepharon filiforme adnatum, in an otherwise healthy male neonate, born to healthy parents out of non-consanguineous marriage. Newborn presented with a single band of tissue connecting left upper and lower eyelid, resulting in limited palpebral aperture opening. Antenatal history was normal. The baby was operated on the seventh day of life under local anesthesia. The eyelid band was excised at the level of each lid margin resulting ...

 Open Access DOI:10.23937/2378-3419/1410091

Which Has Better Dosimetry in Retroperitoneal Sarcoma: Rapid Arc or 3D Conformal Radiotherapy Techniques?

MW Hegazy, B Moftah and O Hassad

Article Type: Research Article | First Published: April 26, 2018

Our study was on 10 patients with RPS diagnosed and treated at king Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia, planned for pre or postoperative radiation therapy with prescribed dose of 45Gy in 25 fractions. In both techniques, we looked at planning target volume (PTV) coverage, dose homogeneity and organs at risk dose (stomach, bowel, liver, kidneys and spinal cord)....

 Open Access DOI:10.23937/2378-3001/1410073

Rotigotine in Parkinson's Disease Patients: What is the Efficient and Tolerable Dose According with the Real Clinical Practice? An Open, Non-Controlled Multicenter Spanish-Study

Salazar G, Fragoso M and Codas J

Article Type: Original Article | First Published: April 26, 2018

Rotigotine is dopaminergic agonist (DA) with a high affinity for D3-dopaminergic receptors delivered through trans-dermal patch which has shown efficacy and tolerance in Parkinson's disease patients (PD) according with some articles published in the past. Whereas, most of the studies published on Rotigotine have shown efficacy to ameliorate the cardinal symptoms of PD at daily dose of 8 Mgs....