Open Access DOI:10.23937/2474-3682/1510089

A Rare Case Report: Urothelial Carcinoma Arising from a Bladder Diverticulum

Hasan Erdogan, Serdar Arslan, Fatih Oncu, Nahide Baran, Fatma Zeynep Arslan and Mehmet Sedat Durmaz

Article Type: Image Article | First Published: May 04, 2018

A 73-year-old man was admitted our hospital with gross hematuria. Abdominal ultrasonography (US) and computed tomography (CT) revealed a bladder diverticulum with a irregular wall thickening that was concerning for tumor (Figure 1). Subsequent cystoscopy and transurethral resection of bladder tumor revealed urothelial carcinoma. Cystoprostatectomy was performed and revealed invasive urothelial carcinoma in the diverticulum extending through the diverticular wall and into peridiverticular adipose...

 Open Access DOI:10.23937/2474-3682/1510088

Black Henna Contact Eczema: Getting Handsome with Poison

Mohamed El Amraoui, Ahmed Bouhamidi, Karima Senouci and Badreddine Hassam

Article Type: Image Article | First Published: May 04, 2018

Black henna contact eczema is common and continues to increase. Paraphenyldiamine (PPD) in addition to its systemic toxicity not only exposes to a selective allergy to (PPD) but also to several of these derivatives and metabolites with cross reactions. We present a case of this irreflected practice....

 Open Access DOI:10.23937/2474-3682/1510087

Giant Inguinal Mass Diagnosed as Testicular Mixed Germ Cell Tumor

Hasan Erdogan, Fatih Oncu, Serdar Arslan, Fatma Zeynep Arslan, Mehmet Sedat Durmaz and Ismet Tolu

Article Type: Image Article | First Published: April 05, 2018

A 19-year-old man was admitted our hospital with right inguinal mass. Ultrasonography (US) showed an irregular, heterogeneous mass lesion in the right ingunal region. Right testis was not seen in scrotum. The patient had no history of any operation. Magnetic resonance imaging (MRI) demonstrated a giant mass which was size of 24 × 17 × 15 centimeter. The mass was hypointense on T1-weighted images, heterogeneous hyperintense on T2-weighted images and heterogeneous contrast enhancement was observ...

 Open Access DOI:10.23937/2474-3682/1510086

Cutaneous Horn of the Eyelid: The Tip of the Iceberg

Mohamed El Amraoui, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Image Article | First Published: April 04, 2018

A 35-year-man, without significant pathological history, with a notion of significant solar exposure seen his profession. Has consulted for a verrucous tumor of the free edge of the right upper eyelid, obstructing the vision, longer than broad, measuring about one centimeter, rolled up on itself with an erythematous base surmounted by a yellow keratin (Figures 1 and Figure 2). View the young age of the patient, the typical character of the lesion and the first episode of the disease, an electro ...

 Open Access DOI:10.23937/2474-3682/1510085

Serious Erysipelas Revealing an Iatrogenic Hematotoxicity to Tamoxifen

El Amraoui Mohamed, Meziane Mariam, Ismaili Nadia, Benzekri Laila, Senouci Karima and Hassam Badredine

Article Type: Image Article | First Published: April 02, 2018

Tamoxifen is an anti estrogen recommended in the treatment of estrogendé pendants cancers. Its side effects are rare and haematological toxicity is extremely rare. We relate an original case of severe erysipelas which revealed a toxic myelopathy to tamoxifen....

 Open Access DOI:10.23937/2378-3664/1410021

Aptamer-Conjugated Magnetic Bead Pull Down and Detection of Human Growth Hormone Releasing Peptides from Serum and Urine by Mass Spectrometry

John G Bruno and Taylor Phillips

Article Type: Research Article | First Published: April 30, 2018

DNA aptamers were developed against human growth hormone releasing peptide (GHRP)-6 and the major metabolite of GHRP-2 (pralmorelin) known as AA-3 (D-Ala-D(β-naphthyl)-Ala-Ala-OH) in 10% human serum or 50% human urine. The lead 5'-biotinylated candidate aptamers from ELISA-like microplate screening were conjugated to commercially available Dynal™ streptavidin-polystyrene-coated 2.8 µm diameter magnetic (magnetite) microbeads (MBs) and used to "pull down" and purify or enrich for their cognat...

 Open Access DOI:10.23937/2469-5734/1510051

Anatomy of the Inferior Alveolar Nerve in Rabbits and its Block Anesthesia

Yong-Di Li, Zheng-Long Tang, Jian-Qin Tan, Dong-Xiang WANG and You-Li Chen

Article Type: Research Article | First Published: May 04,2018

This study performed an anatomical investigation of the mandible and inferior alveolar nerve in rabbits to provide an anatomical basis for the establishment of animal models for mandibular experiments and the implementation of block anesthesia in the inferior alveolar nerve....

 Open Access DOI:10.23937/2378-3656/1410208

Sunitinib Induced Cytopenia in Metastatic RCC

Aykut Bahceci, M Metin Seker, Turgut Kacan, Nalan Akgul Babacan, Birsen Yucel and M Asım Gedikli

Article Type: Case Report | First Published: March 30, 2018

Most malignant kidney tumors are renal tubular epithelium derived adenocarcinomas and referred to as renal cell carcinoma (RCC). Kidney cancer accounts for 3-4% of adult cancers and one third of the overall cases of RCC are diagnosed at the advanced stages of the disease. RCC is a chemo-radioresistant cancer. Therefore, immunomodulatory agents and tyrosine kinase inhibitors (TKI) are commonly used in the treatment of mRCC....

 Open Access DOI:10.23937/2469-5858/1510042

Metabolic Syndrome and Neurodegenerative Diseases

Gizem Yalcin and Abdullah Yalcin

Article Type: Mini Review | First Published: May 02, 2018

Neurodegenerative diseases are progressive disorders that affect central nervous system and gradually worsen over time. Despite many experimental and clinical studies being performed, no effective cure has been found yet. Protein aggregation, excitotoxicity, neuronal death, inflammation, mitochondrial dysfunction, oxidative stress and metabolic syndrome are among the major role players in neurodegeneration. Increasing evidence demonstrates that metabolic syndrome is interrelated with many neurod...

 Open Access DOI:10.23937/2469-5858/1510041

Visual Impairment Contributes to Frailty among a Group of Healthy Community Dwelling Older Population

Miu Ka Ying Doris

Article Type: Original Article | First Published: April 30, 2018

Research studies have shown that visual ability is of considerable importance for daily living and social functioning. Loss of vision or its limitation can be hazardous to independent living and quality of life. Deficits in vision and the ability to respond to visual cues can cause incorrect sensory inputs and lead to difficulties in perceiving the geographical environment, hazards and moving stimuli....