Open Access DOI:10.23937/2378-3656/1410235
Painless Thyroiditis Induced by Immune Checkpoint Inhibitors in a Patient with Small Cell Lung Cancer
Maria Jose Burches Feliciano, Antonia Perez Lazaro and Juan Francisco Merino Torres
Article Type: CASE REPORT | First Published: September 14, 2018
New antineoplastic agents consisting of specific monoclonal antibodies which enhance the host's immune response against the tumoral cells are becoming more common in clinical practice. Ipilimumab, an antibody that blocks the cytotoxic T-lymphocyte antigen 4 (CTLA-4), and nivolumab, a programmed cell death 1 (PD-1) inhibitor are now approved for several advanced neoplasias such as melanoma, non-small cell lung cancer and renal cell carcinoma....
Open Access DOI:10.23937/2378-3656/1410234
Fatal Side Effect of Treprostinil - Hypoglycemia: A Case Report
Dongling Luo, Caojin Zhang and Yigao Huang
Article Type: CASE REPORT | First Published: September 12, 2018
Treprostinil is generally safe and efficacious prostacyclin analog that is recommended for patients with NYHA class III/IV pulmonary hypertension. The reported side effects of standard dosing of treprostinil include fatigue, facial flush, headache, chest pain, dyspnea, right ventricular heart failure and pallor. Other side effects include abdominal cramping, diarrhea, jaw pain, edema, vasodilation and nausea [1]. Hypoglycemia as a side effect of treprostinil is extremely rare. We report the firs...
Open Access DOI:10.23937/2378-346X/1410091
Iron-Overload, Oxidative DNA Damage and Differential Transcript Expression of Iron Homeostasis Genes in Human Cortical Cataracts
Sankaranarayanan Rajkumar, Nair Gopinathan Vidya, Darshini Ankit Ganatra and Abhay Raghukant Vasavada
Article Type: ORIGINAL RESEARCH | First Published: September 10, 2018
The purpose of the study is to determine the level of iron, its role in oxidative damage and to profile and measure the level of transcript expression of genes responsible for iron homeostasis in lenses of human cataracts. Human whole lenses (WLs) were obtained from donors' eyes (n = 33) within 8 hours of death. A total of 167 (control, n = 35 and cataract, n = 132) anterior central capsules (ACC) harboring lens epithelial cells (LECs) and lens aspirate containing LECs, primary and secondary len...
Open Access DOI:10.23937/2469-5793/1510089
Social Networking Sites (SNSs) Addiction
Basem Abbas Al Ubaidi
Article Type: REVIEW ARTICLE | First Published: September 10, 2018
Social Networking Sites (SNSs) in our lives are an essential computer-generated combination regarded as a 'global customer phenomenon'. In recent times, as statistics have shown, this phenomenon daily records a dramatic increase in its users. It is a state of mental addiction, an illness if you may so call it for some users. It has been noted that some extroverts use social networks for social augmentation, whereas introverts use it for social compensation. Addicted customers mostly deal with lo...
Open Access DOI:10.23937/2469-5793/1510088
Control Excessive Anger before it Controls Your Life
Basem Abbas Al Ubaidi
Article Type: REVIEW ARTICLE | First Published: September 10, 2018
There is usually a public misconception between anger, aggression, and hostility. Anger is a sense of emotion that ranges from the standard reaction of mild irritation to the intense response of fury and rage. Anger becomes a dilemma if it felt too intensely, frequently, expressed inappropriately and associated with extreme physical/mental strain on the individual. On the other hand, aggression is an often-violent behavior that causes harm or injury to another person or property. While, hostilit...
Open Access DOI:10.23937/2469-5750/1510061
Resveratrol, Blueberry, Cranberry and Raspberry Exhibit Protection Effect to Photodamaged Hair
Julia de Souza Gomes, Marina Silva Rita, Joao Marcos da Cunha Altomare, Nadia Rezende Barbosa Raposo, Marcos Antonio Fernandes Brandao and Hudson Caetano Polonini
Article Type: RESEARCH ARTICLE | First Published: September 07, 2018
When hair is exposed to the sun there may occur protein degradation, which alters its physical appearance. Thus, beneficial hair adjuvants with addition of natural sunscreens are sought for cosmetics development. In this study, we developed hair conditioning products containing blueberry, raspberry, cranberry and resveratrol in different proportions, incorporated into TrichoCond®. In vitro photoprotection capacities of the products and cystine content of the hair samples after treatments were d...
Open Access DOI:10.23937/2377-4630/1410072
When Equipment Misbehaves: Severe Respiratory Acidosis Resulting from a Compromised Coaxial Circuit
Anh Q Dang, Marc Rozner, Nicole Luongo and Shital Vachhani
Article Type: CASE REPORT | First Published: September 07, 2018
The construction of a coaxial circle breathing circuit encloses the inspiratory limb within the expiratory limb to preserve heat, humidity, anesthetic gas, and oxygen. However, the construction also makes kinks or breaks in the enclosed inspiratory limb difficult to detect. With kinking or disconnection of the central inspiratory limb, the patient may rebreathe expiratory gases, leading to a significant increase in dead space and concomitant respiratory acidosis. We describe a clinical case in w...
Open Access DOI:10.23937/iaoms-2017/1710010
Advanced MRI Sequences (Diffusion and Perfusion): Its Value in Parotid Tumors
Merino Domingo F, Martin Medina P, Lopez Fernandez P, Zafra Vallejo V, Salvador Alvarez E, Gutierrez Diaz R, Sanchez Aniceto G and Ramos A
Article Type: RESEARCH ARTICLE | First Published: September 07, 2018
Tumors of salivary glands constitute 3% of neoplasms of the body. Clinical signs and symptoms usually occur in tumors at advance stages. Dynamic-contrast-enhanced and diffusion-weighted MR sequences have been described as useful diagnostic tools in other locations. Our goal is to evaluate the utility of these techniques for parotid tumors. We retrospectively reviewed the Parotid tumors operated by our department whit Dynamic-contrast-enhanced and diffusion-weighted MR sequences between 2012 and ...
Open Access DOI:10.23937/iaim-2017/1710004
A Complicated Tonsillitis: Lemierre's Syndrome
Moreno Diaz Javier, García Brunen Jose Miguel, Loscos Aranda Silvia and Arenas Miquelez Aranzazu Inmaculada
Article Type: CASE REPOR | First Published: September 07, 2018
Lemierre's syndrome is a rare complication of tonsillitis, with septic emboli and jugular vein thrombosis. We present a case in a young adult without immune deficiencies that required purulent collection drainage and admission to the Intensive Care Unit. This entity, although rare, is potentially fatal and should be known for early diagnosis and treatment....