Open Access DOI:10.23937/2377-3634/1410105

Effects of Fractionated Neem Leaf Extract (IRC) on Blood Glucose Level in Alloxan Induced Diabetic Wistar Rats

Okpe Aaron C, Shu Elvis N, Nwadike kenneth I, Udeinya Iroka J, Nubila, Nkoyo I and Aniagor Ebele N

Article Type: Research Article | First Published: April 04, 2019

This study evaluated the hypoglycaemic effects of fractionated neem leaf extract (IRC) on alloxan induced diabetic wistar rats. IRC dissolved in phosphate buffered saline (PBS) PH 7.2 was administered as 50 mg/kg, 500 mg/kg, 1000 mg/kg, 2000 mg/kg single doses and 5 mg/kg, 50 mg/kg, 250 mg/kg and 500 mg/kg repeated doses in the diabetic rats while in the normoglycaemic rats 100 mg/kg and 250 mg/kg were used respectively. The positive control groups received single and repeated doses of glibencla...

 Open Access DOI:10.23937/2377-9004/1410143

A Large Uterine Leiomyoma with Hypertrophied Omental Vessels: A Case Report

Ayse Nur Aksoy, Ebru Bulut Erdem, Gülsah Tanas Sarıkas and Elçin Telli

Article Type: Case Report | First Published: March 29, 2019

Uterine leiomyomas are the most common solid benign uterine neoplasms that arise from the overgrowth of smooth muscle and connective tissue in the uterus. It is estimated that 20-40% of women of reproductive age have uterine leiomyoma; the prevalence increases during the reproductive age and decreases after menopause. Uterine leiomyomas have been classified according to their location: Submucosal, intramural, subserosal. While subserosal uterine leiomyomas are usually asymptomatic; intramural an...

 Open Access DOI:10.23937/IJDA-2017/1710011

Meaning and Agency in Biological Autonomy: The Motor Image in Self Integration

Denis Larrivee

Article Type: Review Article | First Published: March 29, 2019

Understanding the physical basis for mediating personal integration constitutes an important domain of investigation for physical and mental health. Among its singular determinants are behavioral influences that plastically shape integration through motor plans and executed movements, and which also fundamentally contribute to cognition. A key requirement of the motor plan is that of framing motions in the context of an agent, where the body is appropriated as an origin of action emergence. Embo...

 Open Access DOI:10.23937/IACPH-2017/1710002

The Impact of Thyroid Autoantibodies Positivity on In Vitro Fertilization Outcome: A Comprehensive Review

Sokratis Grigoriadis, Evangelos Maziotis, Mara Simopoulou, Konstantinos Sfakianoudis, Polina Giannelou, Anna Rapani, Petroula Tsioulou, Agni Pantou, Despina Tzanakaki, Konstantinos Pantos and Michael Koutsilieris

Article Type: Research Article | First Published: March 28, 2019

In Vitro Fertilization (IVF) has been employed for more than four decades. A crucial concern is the etiology of infertility due to the fact that it may range widely, from reproductive system anatomy and endometrium receptivity to multisystem disorders and several immunologic factors. Among the immune pathologies that could compromise fertility are the autoantibodies affecting thyroid function. Infertile women are in a great prevalence of thyroid autoimmune disorders. However, there are still uns...

 Open Access DOI:10.23937/2469-5718/1510122

Characterization of Exercise-Induced Cytokine Release, the Impacts on the Body, the Mechanisms and Modulations

Katsuhiko Suzuki

Article Type: Review Article | First Published: March 28, 2019

The objective of this review is to introduce significant research findings mainly on cytokine responses to exercise. First, some basic background information on cytokines is provided. Then, some of our data according to exercise modes and key experimental research on the factors affecting cytokine responses to exercise are explained. Furthermore, the mechanisms and modulations of the cytokine responses are described to understand stress and inflammatory reactions and their prevention/recovery......

 Open Access DOI:10.23937/RMI-2017/1710010

The Effect of Different Sperm Concentration in Semen on Clinical Outcomes of In Vitro Fertilization (IVF) and Intracytoplasmic Sperm Injection (ICSI): Retrospective Study

Teresa Wiesak, PhD, Robert Milewski, PhD, Kerri King, BSc, Andrew Atkinson, MD and Allen Morgan, MD

Article Type: Review Article | First Published: March 28, 2019

The objective of this retrospective study was to determine whether clinical outcomes (clinical pregnancy, implantation, live births and miscarriage) were affected by the application of IVF or ICSI insemination with different sperm concentrations in ejaculate in unselected population of infertility patients. Data of 786 in vitro fertilization (IVF) and 1268 intracytoplasmic sperm injection (ICSI) cycles were retrieved and analyzed according the stratification of the cycles as follows: Group with ...

 Open Access DOI:10.23937/2572-3235.1510044

DIBH-VMAT for Consolidation RT in Mediastinal B-NHL can Significantly Reduce Doses to OAR Report of Two Cases

Antje Fahrig, PD, Th Koch, Ch Heine, MSc, M Lenhart and L Fischer von Weikersthal

Article Type: Case Report | First Published: March 27, 2019

Consolidative radiotherapy after immuno-chemotherapy in localized bulky diffuse large B-cell lymphoma (DLBCL) patients significantly improves both, overall and progression-free survival and treatment is in principle curative. Therefore protection of organs at risk is highly relevant. Two 53-years and 18-years old patients with bulky mediastinal DLBCL were planned with and without deep inspiration breath-hold (DIBH) and volumetric modulated arc therapy (VMAT). DIBH reduced the doses to the heart ...

 Open Access DOI:10.23937/IACOD-2017/1710011

Genes Involved in the Development of Autism

Ines Lopes Cardoso and Sandra Almeida

Article Type: Research Article | First Published: March 27, 2019

Autism is still considered a very complex disease, since it has diverse etiology, with multiple factors apparently associated with its appearance. However, none of them reveals to be totally responsible for its development. Nowadays, this disorder is considered to have a strong genetic component with the interaction of several genes. Furthermore, other diseases with well-known etiology might also be related with autism. The aim of this review is to discuss, through bibliographic search, genetic ...

 Open Access DOI:10.23937/2378-3656/1410260

Shear Wave Elastography: A New Assistant Modality in the Diagnosis of Hamartoma

Aysegul Altunkeser and Fatma Zeynep Arslan

Article Type: Case Report | First Published: March 27, 2019

Shear wave elastography(SWE) is a relatively new, promising modality which enables detailed information about tissues mechanical properties. Hamartomas are relatively rare, soft benign breast lesions comprised of glandulary and stromal components. The importance of radiological imaging methods increases especially in cases who do not have the typical appearance of hamartomas. Mammography and sonography are effective methods in evaluating morphological features of lesions. However, typical hamart...

 Open Access DOI:10.23937/2378-3656/1410259

Shear Wave Elastography as an Early Indicator of Breast Cancer in a Breastfeeding Patient: A Case Report and Literature Review

Aysegul Altunkeser and Fatma Zeynep Arslan

Article Type: Case Report | First Published: March 25, 2019

Shear wave elastography (SWE) is a relatively new and highly effective method to reveal mechanical features of tissue by demonstrating quantitative elasticity value. The morphological features including margin of the lesion, orientation, shape and border are considered in differentiation of breast lesions on USG. It is a known fact that malignant lesions are usually palpated as a hard mass in the physical examination. A qualitative broad information can obtain about the tissue elasticity by inte...