Open Access DOI:10.23937/2474-3674/1510074
Enhancement of NK Cell Cytotoxicity against MDA-MB-231 Cell by Presence of OK432
Sellamuthu Subbanna Gounder, Rafeezul bin Mohamed and Baskar Subramani
Article Type: Original Article | First Published: April 12, 2019
Several advancements are made in the field of immunotherapy for enabling an effective cure for cancer. Treatments are being approached with multipronged approach with combination therapies as well as by gene therapy. Cancer incidence however progressing further mainly due to the changes in lifestyle. Epidemiological surveys indicate that cancer incidence is being more predominant in females; in particularly breast cancer is the most common diseases throughout world. However, the treatments attem...
Open Access DOI:10.23937/2474-3674/1510073
The Importance of Detecting Regulatory T Cells in Neonatal Sepsis
Yao Yu, Yingzuo Shi and Yisen Zhang, MD
Article Type: Short Review | First Published: April 11, 2019
Sepsis is a deadly complication of pediatric infection. Tregs are a typical subset of lymphocytes showing immune suppressive function. Tregs show grateful influence to immune system in neonatal sepsis. The proportion of Tregs relate with inflammatory response, Oxidative stress sepsis and this would be a new curing targeting to immunotherapy. In this short review, we analysis the research findings of Tregs in neonatal sepsis and emphasize the significance of Tregs. Sepsis is a common critical ill...
Open Access DOI:10.23937/2378-3419/1410108
Well Differentiated Neuroendocrine Uncommon Primary Breast Carcinoma: A Case Report
Angela Strazzanti, MD, Claudio Trovato, Angelo Caponnetto, Santi Gangi, Loredana R Villari, Pietro Gangemi and Francesco Basile
Article Type: Case Report | First Published: April 11, 2019
Neuroendocrine breast carcinomas (NEBC) are rarely malignant with a frequency of less than 0.1-0.3% of all breast tumors. The actual incidence of NEBC in BC (Breast Cancer) populations being still largely unknown due to the lack of a clear cut diagnostic criteria. In 2003, the World Health Organization (WHO) Classification of Tumors of the Breast and Female Genital Organs definitely established that the immunohistochemical expression of NE markers is the unique requirement for NEBC diagnosis....
Open Access DOI:10.23937/IJDA-2017/1710012
Biopsychosocial Stressors in Pre-liver Transplant Patients: A Case Series
Mahdod Eftekar, MD, FRACGP, FRANZCP
Article Type: Case Series | First Published: April 13, 2019
Liver transplant candidates undergo multiple stressors due to the complexity of the medical, social and psychological circumstances about the transplantation. These stressors may predispose candidates to psychiatric disorders or acopic responses. Authors looked at the medical documents of 43 transplant candidates referred from Jan 2015 to May 2018 retrospectively. The biopsychosocial stressors extracted from the psychiatrist and social worker's notes....
Open Access DOI:10.23937/2378-3656/1410263
Staphylococcemia due to Cosmetic Doping: An Important Etiology of Fever of Undetermined Origin
Ronisie Duarte de Oliveira, Raquel Rodrigues Ferreira Rocha de Alencar, Bruno Vianei Real Antonio, Andre Luiz Tiuba Mendonca and Aryadine Allinne Machado de Miranda
Article Type: Case Report | First Published: April 13, 2019
A new problem, called cosmetic doping, has been inserted globally for some decades, and has grown in importance in Brazil in recent years, affecting athletes and non-athletes. The cosmetic doping consists in the use of oily substances by the intramuscular route to increase volumetrically the muscle, which can lead to the formation of oil deposits in the muscle, called oleomas, necrosis, physical deformities and even death. We present a 31-year-old male patient who sought the emergency room with ...
Open Access DOI:10.23937/2572-4061.1510021
Public and Environmental Health Effects of Plastic Wastes Disposal: A Review
Okunola A Alabi, Kehinde I Ologbonjaye, Oluwaseun Awosolu and Olufiropo E Alalade
Article Type: Review Article | First Published: April 12, 2019
Since 1950 to 2018, about 6.3 billion tonnes of plastics have been produced worldwide, 9% and 12% of which have been recycled and incinerated, respectively. Human population increase and consistent demand for plastics and plastic products are responsible for continuous increase in the production of plastics, generation of plastic waste and its accompanied environmental pollution. We have reviewed in this paper, the most relevant literatures on the different types of plastics in production, the h...
Open Access DOI:10.23937/2469-5777/1510071
Use of Mouthguards by Amateur Basketball Athletes in Greece and The USA
Elena-Lito Exarchou, Ioannis Kotsanos and Nikolaos Kotsanos
Article Type: Original Article | First Published: April 11, 2019
Mouthguard use reduces the consequences of oral trauma in sports with intense physical contact. The use of mouthguards is recommended by the Academy for Sports Dentistry for all sports involving physical contact and collision, and by the American Academy of Pediatric Dentistry for sports in which orofacial injury can occur, e.g. basketball. The aim of this study is to evaluate mouthguard use and relative knowledge by male amateur Greek and collegiate American basketball athletes....
Open Access DOI:10.23937/IJND-2017/1710007
Identification of PSEN1 and PSEN2 Gene Variants and Clinical Findings with the Literature
Nadide Cemre Randa, Elçin Bora, Esra Ataman, Ozlem Oz, Gorsev Yener and Ayfer Ulgenalp
Article Type: Original Article | First Published: April 11, 2019
Alzheimer's disease is an age-related and irreversible disease and characterized progressively decline in cognitive functions such as memory, speech, executive functions and visual-spatial skills. Currently, there is no a simple and definitive diagnosis method for clinical management. It is possible to diagnose with 85-90% accuracy with clinical assesment and neuropsychological tests. The precisely-known risk factors associated with Alzheimer's disease are aging, family history, and the presence...
Open Access DOI:10.23937/2474-3674/1510072
Assessment of the Degree of Stress during Pediatric Ground Transport
Carme Alejandre, MD, David Vila, PhD, Ana Olego, M Jose Tovar, Angels Llorens, Marta Hernandez, M Paz Larrosa and Elisabeth Esteban, PhD
Article Type: Original Research Article | First Published: April 11, 2019
A total of 220 patients were included, of whom 135 were male (61.4%) with a median age of 2.5 months (IQR 3 days-21 months). Median transfer time was 29 minutes (IQR 13-52 minutes). Sixty-three patients needed non-invasive ventilation (28.6%). The median score before the transfer was 16 (IQR 15-19) and after it 16 (IQR 14-18). In 23 cases (10.5%) patients were accompanied by their parents in the ambulance; no statistically significant differences were observed in the value of the score (p 0.959)...
Open Access DOI:10.23937/iacvd-2017/1710016
Magnitude of Cardiovascular Risk Factors among Adult Hypertensive Patients Attending in Ayder Comprehensive Specialized Hospital, Ethiopia, 2018
Degena Bahrey, Tekleweyni Mariye, Gebreamlak Gebremedh, Ayehu Kassa, Alem Girmay, Girmay Teklay, Hagos Tasew, Hagos Berihu and Yohannes Ashebir
Article Type: Research Article | First Published: April 10, 2019
A total of 578 hypertensive patients were taken from cardiac follow-up. Among the hypertensive patients the magnitude of cardiovascular risk factors was 212 (36.7%). The magnitude of each cardiovascular risk factor was high. Magnitude of overweight and obesity was 33.7%. Concurrently 30.4% had habit of taking high salt diet and 27.3% were patients with dyslipidaemia. Patients with less physically active were 89.1% and 23.5% were consuming alcohol regularly. Whereas 15.9% was smoker. This study a...