Open Access DOI:10.23937/2643-4539/1710012

Obesity may Increase the Prevalence of Parkinson’s Disease while Parkinson's may Reduce Obesity Index in Patients

Muslimat Kehinde Adebisi, Ehianeta Teddy, Mzee Said Abdulraman Salim, Liuyi, Abdul Nazif Mahmud, Aaron Gia Kanton and Abdullateef Taiye Mustapha

Article Type: Research Article | First Published: October 14, 2019

Currently Parkinson's disease is becoming more common among younger people of ages from 30-40 years. The incidence is higher among patients with higher BMI, some reports has it that Obesity is a risk factor for Parkinson’s disease while some reported that there is no relationship between obesity and Parkinson’s disease. Parkinson’s disease patient at the time of diagnosis has a above normal BMI but this goes below normal as the disease progresses. Therefore, it is important to explore the ...

 Open Access DOI:10.23937/2643-3885/1710036

Surgical Management of Foot Macrodystrophia Lipomatosa in Adults: Case Report of Surgical Technique

Reema Alhussein and Mohammed Alshouli

Article Type: Case Report | First Published: October 02, 2019

Macrodystrophia lipomatosa is a rare congenital anomaly causing localized or generalized gigantism. Characterized by an abnormal excessive growth of mesenchymal elements in particularly fibro-adipose tissue, bone, tendon, nerves and vessels. We report our experience in surgical management of a case with Macrodystrophia lipomatosa involving the second toe of the left foot. A through clinical and radiological assessment followed by surgical second ray amputation and soft tissue debulking of the le...

 Open Access DOI:10.23937/2377-3634/1410113

Effect of Antihypertensive Agents on Biochemical Parameters in Diabetic Patients in Taif - KSA

Niveen M. Daoud, Ola A. Qadi, Dania O. Al-talhi and Hanan Kamal Al-sharabi

Article Type: Clinical Study | First Published: October 21, 2019

Hypertension and diabetes mellitus are chronic medical conditions that frequently coexist. Our objective is to evaluate the effect of Angiotensin converting enzyme inhibitors and Angiotensin II receptor blockers comparatively and in integration with Metformin, dipeptidyl 4 inhibitors and insulin on lipid profile, serum creatinine, liver enzymes and electrolytes in type II diabetic patients. Hypertension and diabetes mellitus are chronic medical conditions that frequently coexist. Obesity, high s...

 Open Access DOI:10.23937/2378-3419/1410126

Cancer Patterns in Odisha - An Important Mining State in India

Sharmila Chatterjee, MBBS, MPH, CPH, Paul H Levine, MD, Surendra Nath Senapati, MD, Dipti Rani Samanta, MD and Pinaki Panigrahi, MD, PhD

Article Type: Original Research | First Published: October 14, 2019

Odisha, a populous state and a major mining belt in India has high levels of environmental carcinogens. There is no population-based cancer registry in Odisha, thus giving no opportunity to develop systematic studies on important regional carcinogens. This paper highlights current patterns of cancer as seen at Acharya Harihar Regional Cancer Centre (AHRCC), and provides the first opportunity to determine the most important research questions that could drive cancer control programs in Odisha. Tw...

 Open Access DOI:10.23937/2378-2951/1410160

Safety of Hydrochlorothiazide in the Real World: A Commentary on the Italian Medicines Agency (AIFA) Pronouncements

Valerio Massimo Magro, MD, Carla Coppola, MD, Eugenio Boccalone, MD, Michele Caturano, MD, Giovanni Scala, MD and Walter Verrusio, MD, PhD

Article Type: Commentaries | First Published: October 14, 2019

Thiazide diuretic drugs are the most commonly used molecules for the treatment of systemic hypertension. Despite their established role in the treatment of this disease, well recognized by the guidelines of national (such as the Italian Society of Cardiology - SIC - for example, which incorporates the directives of the European Society of Cardiology - ESC -) scientific societies. Several evidences have shown that hydrochlorothiazide therapy in chronic renal disease with advanced grade of kidney ...

 Open Access DOI:10.23937/2469-5831/1510022

Child Mortality: A Comparative Study of Some Developing Countries in the World

Ilker Etikan, Ogunjesa Babatope, Kabiru Bala and Savas Ilgi

Article Type: Research Article | First Published: September 30, 2019

According to the United Nations Sustainable Development Goals, countries all over the world are expected to create a healthy living environment for the populace most especially the vulnerable population of which children are examples. Despite the reducing trend in the under-five mortality rate in some developing nations, some nations still have a high record of under-five mortality. This study adopted the use of a One-way Analysis of Variance (ANOVA) to evaluate any significant difference in the...

 Open Access DOI:10.23937/2469-5742/1510062

Risk Factors for Urinary Tract Infection in Men Treated with Transurethral Resection of the Prostate for Lower Urinary Tract Symptoms

J Stangl-Kremser, S Bronimann, M Abufaraj, C Pozo, SF Shariat and G Schatzl

Article Type: Research Article | First Published: October 14, 2019

Our cohort comprised 96 consecutive patients treated with TURP for obstructive lower urinary tract symptoms associated with benign prostatic enlargement suggestive of benign prostate hyperplasia. We collected relevant data of our cohort including demographic data, comorbidities, past medical history presence of preoperative indwelling transurethral catheter and histopathology of prostate chips after resection were assessed for each patient. Patients’ charts were also reviewed to ascertain the ...

 Open Access DOI:10.23937/2469-5742/1510061

Holmium Laser Lithotripsy: In-Vitro Investigation of Optimum Power Settings in Fragmentation, Dusting and Propulsion and Stone Breaking Times

Mehmet Solakhan

Article Type: Research Article | First Published: October 14, 2019

An experimental urinary system model was created. Stones previously taken during the operation were used for the procedure. For this purpose, stones with Ca-oxalate and Ca-phosphate were used. Kidney and ureter model was prepared under laboratory conditions. Irrigation catheter with a lumen of 15 mm was used for the ureter model. 9F rigid ureterorenoscope (Storz/Germany) was used to reach the stone. DORNIER MEDILAS H SOLVO/30 W-Germany laser was used for stone crushing. 275 and 550 microfibers w...

 Open Access DOI:10.23937/2643-4512/1710029

Determinants of Children Under-Five Mortality in Cambodia: Analysis of the 2010 and 2014 Demographic and Health Survey

Vanthy L, Chhorvann C, Bunleng H and Sopheab H

Article Type: Original Articl e | First Published: October 14, 2019

Despite declining rates for children under five years of age (U5M) in the last ten years, developing countries continue to challenge to meet Sustainability Development Goals (SDG) target, including reducing neonatal mortality to 12 deaths, and U5M to 25 deaths per 1,000 live births, by 2030. Cambodia, located in Southeast Asia, recently been reclassified by the World Bank as a lower middle-income country. Cambodia U5M has declined over the last decade, and Cambodia achieved the Millennium Develo...

 Open Access DOI:10.23937/2643-4016/1710014

Femur Stress - Can You Take It?

Saagar Patel, MD, Areeb Masood, MD, Girija Rajakumar, MD, Pritish Bawa, MD, Haitham Awdeh, MD and Manickam Kumaravel, MD

Article Type: Research Article | First Published: October 07, 2019

Outline the biomechanics and pathophysiology of stress-induced injuries to the femur. Provide various imaging presentations of stress injuries of the femur including radiographs, computed tomography (CT), and Magnetic resonance imaging (MRI). Understand treatment modalities, recognize complications and become proficient in avoiding pitfalls. This paper will discuss detailed macro and microanatomical features of the femur and associated soft tissues such as muscles, tendons, and cartilage. A revi...