Open Access DOI:10.23937/2643-4563/1710019

Usefulness of P16 and KI67 Immunostaining in Cervical Smear Cytology in Guatemalan Women: A Cross-Sectional Study

Alberto Garcia, MD, PhD, Angel Velarde, MD, MSCE, Francisco Quereda, MD, PhD, Jaume Ordi, MD, PhD, Orlando Rodas, MD, PhD, Erick Soch, MD, H Arturo Morales, MD, Federico Nave and Carlos Lopez, MD

Article Type: Original Research | First Published: October 18, 2019

Conventional cytology is an economic method for screening abnormalities in cervical smears, but with implications in false positive and false negative as compared to better detection of transformed cells with the Dual staining P16/KI67 proteins in cervical smears, therefore, we evaluate the validity and reproducibility of cytology with double staining of P16 and KI67 as compared to conventional cytology in cervical smears. Participants were 210 Guatemalan women with abnormalities in conventional...

 Open Access DOI:10.23937/2572-4193.1510068

Preoperative Computed-Tomography for Endoscopic Sinus Surgery: A Simplified Checklist

Saad M Alshammari, MD and Nada A Alshaikh, MD

Article Type: Research Article | First Published: October 21, 2019

Endoscopic sinus surgery (ESS) gained growing popularity with indications expanding beyond rhinosinusitis. Preoperative high-resolution computed tomography (CT) scan is essential in providing the surgical map for surgeons. In addition of being a diagnostic imaging technique, it gives valuable information about origin, nature and extension of the pathology to adjacent structures. Therefore, preoperative review of para-nasal sinuses (PNS) CT scan is crucial in order to perform successful and compl...

 Open Access DOI:10.23937/2469-5734/1510102

Alternative Technique for Suture in Surgeries of Mandibles

Geninho Thome, Thomas Berry, Larissa Carvalho Trojan, Carolina Accorsi Cartelli, Marcos Boaventura de Moura and Sergio Rocha Bernardes

Article Type: Case Report | First Published: October 28, 2019

The surgical procedure for dental implants presents predictable long-term results. An important part of the surgical procedure is suture, which plays an important role in healing, reconstructing and remodeling soft tissue and promoting hemostasis of the region. The purpose of this case report is to introduce an alternative technique for performing suture in implant surgery of lower total arch. Four implants were placed in the patient’s jaw, all with a minimum torque of 60 Ncm. A small perforat...

 Open Access DOI:10.23937/2469-5734/1510101

Clinical Trial on the Influence of the Consumption of Dyes during Supervised and Domestic Tooth Bleaching

Natalia Maria Velozo dos Santos, Fernanda Buccolo Losada and Renata Pedrosa Guimaraes

Article Type: Research Article | First Published: October 21, 2019

The demand for a harmonious smile and with whiter teeth is currently one of the main reasons that lead the patient to look for a dental treatment, since the appearance of the smile has great relevance on the psychological and interpersonal aspects. The chromatic change of teeth happens due to extrinsic and intrinsic factors. Changes in intrinsic origin may happen due to systemic diseases, changes in tooth formation, dental trauma, pulpal necrosis, drug use, fluorosis and by the dental aging proc...

 Open Access DOI:10.23937/2643-3907/1710028

Mylohyoid Flap and Platelet Rich Fibrin in the Treatment of Medication Related Osteonecrosis of the Jaws

Michael Erlichman, DDS, Pooja Gangwani, DDS, MPH and Sneha Shah, DMD

Article Type: Case Series | First Published: November 07, 2019

Bisphosphonate medications are widely prescribed for the treatment of osteoporosis and cancer metastases to bone. However, these medications are among a list of agents which are implicated in medication related osteonecrosis of the jaw (MRONJ). A variety of non-surgical and surgical approaches are indicated in the treatment of this condition, depending on disease severity. This case series demonstrates the success of the mylohyoid flap in combination with platelet rich fibrin (PRF) in achieving ...

 Open Access DOI:10.23937/2643-3907/1710027

Dental Rehabilitation in Class III Anomaly with Oligodontia after Palatal Distraction and Osteotomy under Cone-Beam CT Assistance

Manfred Nilius, MD, DDS, MSc, Günter Lauer, MD, DMD, PhD and Matthias C Schulz, DMD, PhD

Article Type: Original Article | First Published: October 28, 2019

Rehabilitation of angle class III deformity concomitant with oligodontia with great functional, esthetic and social impairment for the patient needs a combined orthodontic-surgical treatment. To achieve secure, quick and stable dental and facial rehabilitation, backward planning with cone-beam CT navigation best supports the multidisciplinary approach. Here we show longtime stability of more than 5 years after thoroughly planning, bimaxillary osteotomy with an implant guided transpalatal distrac...

 Open Access DOI:10.23937/2377-9004/1410154

Endovascular Management of Refractory Puerperal Hematomas: A Case Report and Review of the Literature

Simon Bradette, MD, FRCPC, Melissa Marien, MD, PGY-3, Melanie Rousseau, MD, FRCPC, Mathieu Beland, MD, FRCPC and Catherine Lalonde, MD, FRCPC

Article Type: Case Report | First Published: November 06, 2019

Pelvic hematomas can be a serious complication of vaginal delivery. They can be associated with significant morbidity related to blood loss, infection, surgery and blood product transfusion. Reported incidence varies from 1/300 to 1/1500. Operative vaginal delivery and episiotomy are among the most common risk factors associated with puerperal hematomas, but they may also occur in the absence of laceration of the surrounding tissue. They are classified as vulvar, vaginal, vulvovaginal or retrope...

 Open Access DOI:10.23937/2377-9004/1410153

Refractory Hyperemesis Gravidarum in a Patient with Type 1 Diabetes Treated with Laparoscopically Assisted Feeding Jejunostomy Tube Placement

Melissa Chu Lam, MD, Briana Baxter, MD, Farrah Naz Hussain, MD, Kristina Martimucci Feldman, MD and Barak Rosenn, MD

Article Type: Case Report | First Published: November 04, 2019

Severe Hyperemesis gravidarum (HG) is a debilitating condition that affects less than 1% of pregnant women. Management of HG is further complicated in women with type 1 diabetes due to oscillations between hypo and hyperglycemia, often exacerbated by the presence of gastroparesis. We report a 25-year-old G1P0 with longstanding uncontrolled type 1 diabetes mellitus (HbA1C 10.5%), who presented to our service multiple times with hyperemesis and ketosis. On each of these admissions, she was diagnos...

 Open Access DOI:10.23937/2643-4474/1710028

A Review of Radiographic Imaging Findings of Ependymal Tumors

Maria Habib Hanna, MD, Bansal A, MD and Belani P, MD

Article Type: Review Article | First Published: October 24, 2019

Ependymomas are glial tumors that typically arise from the lining of the ventricles or the central canal of the spinal cord. The most common site of occurrence is within the posterior fossa. Subtypes of ependymomas include anaplastic ependymoma, myxopapillary ependymoma, and subependymoma. Its characteristic imaging features include findings of a heterogeneous mass with necrosis, calcifications, cystic changes, and hemorrhage. Treatment options includes partial resection with or without irradiat...

 Open Access DOI:10.23937/2643-4474/1710027

Our First Experience of Simultaneous Endovascular Embolization of Proximal Flow-related Aneurysm and Arteriovenous Malformation of the Brain with Liquid Embolic Agent

AA Sufianov, SM Karasev, RR Khafizov and RA Sufianov

Article Type: Case Report | First Published: October 21, 2019

Arteriovenous abnormalities of cerebral vessels are quite common. One of the main manifestations of this pathology are arteriovenous malformations. Also, a combination of malformations with aneurysmal expansion of the vascular wall of various localization is not rare. The frequent localization of such aneurysms are afferents going to the malformation site; therefore, such aneurysms are also called proximal flow-related aneurysms. As a rule, a combined approach is used mainly for endovascular tre...