Open Access DOI:10.23937/2469-5831/1510026
The Basic Four Measures and their Derivates in Dichotomous Diagnostic Tests
Tadeusz R Ostrowski, MD and Tadeusz Ostrowski, PhD
Article Type: Original Article | First Published: June 05, 2020
The paper focuses on four basic statistics of dichotomous diagnostic tests, i.e. sensitivity, specificity, positive and negative predictive value, and some of their derivates, like Youden index and predictive summary index, and on further derivates of these derivates, i.e. Matthews correlation coefficient (or Yule phi), chi squared test and Cramer’s V coefficient. The paper contains also the necessary and sufficient conditions for a test to be invalid, to be uninformative and the necessary con...
Open Access DOI:10.23937/2469-5696/1410050
Atypical Clinical Picture of Breast Cancer with Dominant Symptoms of Hematologic and Gastrointestinal Malignancies
Malwina Rybicka-Ramos, Grzegorz Kasiarz, Katarzyna Pluta, Tomasz Wilczynski, Jerzy Pruszynski and Ewa Ziolko
Article Type: Case Report | First Published: June 03, 2020
Gastrointestinal malignancy was suspected in a 68-year-old woman with long-term anemia, thrombocytopenia, leukopenia, the presence of fecal occult blood and elevated levels of CEA and CA 19- 9. However, malignancy was not confirmed. The patient was later hospitalized in the Department of Hematology where hematologic disease was excluded. Cervical and inguinal lymphadenopathy and atypical bone marrow cells collected by aspiration biopsy gave rise to the suspicion of bone marrow involvement by tum...
Open Access DOI:10.23937/2377-4630/1410108
Sugammadex-Is Cost the Only Drawback?
Michael W Lew, MD and Joseph Chang, MD
Article Type: Letter to the Editor | First Published: June 04, 2020
Residual muscle paralysis is an important safety issue, with multiple studies demonstrating an association with increased postoperative complications. The pathophysiology of these complications isn’t difficult to explain. One can only imagine the signs and symptoms in an awake patient (i.e. the panic from not having the strength to take a deep breath or move at full strength; the anxiety of not controlling one’s body movement). A study by the Cleveland Clinic demonstrated that major complica...
Open Access DOI:10.23937/2643-3966/1710031
The Usefulness of Long Inflation Balloon Angioplasty Using a Perfusion Balloon for Intracoronary Thrombus
Shingo Watanabe and Michio Usui
Article Type: Case Report | First Published: June 12, 2020
The beneficial effect of percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) has been well established. PCI for ACS, especially for thrombotic lesions, is difficult to treat due to distal embolization or residual thrombus. We experienced a case in which long balloon inflation was effective in PCI for ACS due to thrombotic lesions. Here we introduce the case that long inflation balloon angioplasty using a perfusion balloon was useful in PCI for thrombus lesion....
Open Access DOI:10.23937/2643-3966/1710030
Pacemaker Lead Associated Superior Vena Cava Syndrome Treated By Veno-Atrial Bypass
Thilina Gunawardena, MBBS, MD, MRCS, Balasubramanium Saseekaran, MBBS, MD, MRCS, Gayan Bandara, MBBS, MD, MRCS, Rezni Cassim, MBBS, MS and Mandika Wijeyaratne, MBBS, MS, PhD
Article Type: Case Report | First Published: June 11, 2020
Pacemaker lead associated venous thrombosis is common. However, due to collateral venous drainage those who are affected rarely become symptomatic. Superior vena cava (SVC) syndrome is a constellation of signs and symptoms that occurs as a result of obstruction to flow in the superior vena cava. In this case report we present a patient who developed this complication following multiple transvenous pacemaker wires. After failed percutaneous venoplasty he was treated successfully with a right inte...
Open Access DOI:10.23937/2378-3656/1410313
Multiple Cerebral and Cerebellar Infarctions following Russell’s Viper (Daboia Russelii) Envenomation - A Case Report
UDN Prasad, JMRP Bandara and HMS Senanayake
Article Type: Case Report | First Published: June 13, 2020
Ischemic stroke is a rare neurological complication following SriLankan Russell’s viper envenomation. We report a case of a 44-year-old person, who developed multiple cerebral and cerebellar infarctions following SriLankan Russell’s viper envenomation. The patient developed both local and systemic envenomation and was treated with Snake Venom Anti-Serum I.P. (VinsBioproducts Ltd). On day six, this patient developed left-sided hemiparesis. CT scan of the brain showed bilateral cerebellar, bil...
Open Access DOI:10.23937/2378-3656/1410312
Case Series of Tetanus Diagnosis and Management in Hargeisa City
Hassan Abdi, Ibrahim Caqli, MD, Mustafe Mumin, MD, Jama Osman, MD, Gregory Fricchione, MD, MPH and Zeina Chemali, MD, MPH
Article Type: Case Series | First Published: June 10, 2020
Tetanus is a global infectious disease caused by tetanospasmin toxin produced by the anaerobic clostridium tetani. It affects the brain stem and spinal cord and leads to high morbidity and mortality if untreated. East Africa reports the highest number of cases and the highest fatalities. The objective of this study is to report on five inpatient clinical cases at Hargeisa Group Hospital in Hargeisa City with lessons learned for our team, a way to educate others and advocate for a new governmenta...