Open Access DOI:10.23937/2572-3235.1510066

Expiratory CT: What is Good Enough?

Mary Salvatore, MD, MBA, Lea Azour, MD, Mary O'Connor, KM Capaccione, MD, PhD and David Mendelson, MD

Article Type: Original Research | First Published: September 24, 2020

To determine the difference in craniocaudal dimension of an inspiratory CT scan minus an expiratory CT scan that constitutes an average expiratory effort to potentially exclude air trapping. This study obtained approval from the Institutional Review Board. The craniocaudal dimensions of inspiratory and expiratory chest CT scans of 83 patients were examined by an experienced radiologist (MS with 20 years of experience). The difference between the two measurements, called the Slice Level Differenc...

 Open Access DOI:10.23937/2572-3235.1510065

Dicom Image Anonymization and Transfer to Create a Diagnostic Radiology Teaching File

Brent Burbridge, MD, FRCPC

Article Type: Brief Report | First Published: September 18, 2020

The creation of a digital, Diagnostic Radiology, teaching file system is reliant upon a process for selecting, anonymizing, and exporting Digital Image and Communications in Medicine (DICOM) images from a clinical Picture, Archive, and Communication System (PACS) to the teaching file. A local version of the Medical Imaging Resource Center - Teaching File System (TFS) from the Radiology Society of North America (RSNA) was deployed to create teaching files. Philips, Intellispace PACS, was the sour...

 Open Access DOI:10.23937/2378-346X/1410118

An Analysis of Interstitial Keratitis Secondary to Epstein-Barr Virus

Carl Pellerin, BS, Ethan Thibodeaux, BS, Zhenyang Zhao, MD and Yusra Siddiqui, MD

Article Type: Case Report and Literature Review | First Published: September 17, 2020

Epstein-Barr Virus (EBV), also known as human herpes virus 4, is a DNA virus that causes a range of pathologies. Interstitial keratitis (IK) is a rare manifestation of EBV that is seldomly characterized in the literature. To our knowledge, a review of the clinical presentations and reported treatments of EBV IK has not been conducted. Here, we report a case of EBV IK in a patient and review 14 cases in the literature. The differential diagnosis and identifying clinical characteristics of EBV IK,...

 Open Access DOI:10.23937/2378-3419/1410142

Regeneration Abilities of Vertebrates and Invertebrates and Relationship with Pharmacological Research: Hypothesis of Genetic Evolution Work and Microenvironment Inhibition Role

Luisetto M, Naseer Almukthar, Gamal Abdul Hamid, Ibrahim G, Behzad Nili Ahmadabadi, Ahmed Yesvi Rafa, Ghulam Rasool Mashori, Tuweh Prince GADAMA and Oleg Yurievich Latyshev

Article Type: Research Article | First Published: September 28, 2020

A better understanding of the forces controlling cell growth will be essential for considering wound healing as a fundamental evolutionary with possibility of scar formation and reparative regeneration and the developing effective therapies in regenerative medicine and also in cancer. Historically, the literature has linked to cancer and tissue regeneration- proposing regeneration as both the source of cancer and a method to inhibit tumorigenesis. Aim of this work is to verify similarity and dif...

 Open Access DOI:10.23937/2378-3419/1410141

Circulating Mir-497-5p as a Potential Non-Invasive Molecular Marker for Diagnosis and Prognosis in Mesothelioma

Majed Al Mourgi

Article Type: Research Article | First Published: August 31, 2020

Pleural mesothelioma is aggressive, surgery is the principal treatment. Mesothelioma usually diagnosed in an advanced stage. The present study was conducted to study the circulating MiR-497-5p as a possible non-invasive molecular marker for the diagnosis of mesothelioma and its role in follow-up and prognosis. MiR-497-5p was evaluated in Mesothelioma tissues and the plasma of patients and the plasma of healthy controls. MiR-497-5p was assessed in the plasma of patients before and after surgical ...

 Open Access DOI:10.23937/2378-2951/1410202

Vaping Induced Cardiac Complications - A Smokescreen Coming to Engulf the Heart?

Benji LIM, MB BCh BAO, Sheldon LEE, MBBS and Siang Chew CHAI, MBBS

Article Type: Case Report | First Published: September 26, 2020

E-cigarette usage has been shown to be associated with lung injury. However, there has been limited data of cardiovascular complications in e-cigarette users. We present two patients that developed cardiac complications after recent increased e-cigarette usage - the first with non-ischemic cardiomyopathy after a month of electronic cigarette usage at the highest power setting of 40 Watts, and the second with predominantly non-ischemic cardiomyopathy with underlying single vessel coronary artery ...

 Open Access DOI:10.23937/2469-5696/1410057

Enzyme Activities of Liver Function (Biomarkers) in Sickle Cell Anaemic Patients Attending Sickle Cell Anaemic Centre, Benin City, Edo State, Nigeria

Collins Uchechukwu Obi, Okikioluwa Stephen Aladeyelu, Ijeoma Nnenna Agbiogwu, Nneka Chidimma Agu, Joseph Akinwale Arusiwon and Mercy Oluchukwu Udeh

Article Type: Survey Article | First Published: September 23, 2020

Hundred subjects were involved for this study. The subjects were divided into 2 groups: 50 sickle cell anaemic subjects (20 males and 30 females) and 50 non-sickle cell subjects or control (23 males and 27 females). Sickle cell anaemic subjects were between the age ranges of 15-41 years while control subjects were between 17-31 years. Subjects were both Sickle Cell Anaemic Centre, Benin City, Edo State, Nigeria and volunteer students at the Department Medical Laboratory Science, Ambrose Ali Univ...

 Open Access DOI:10.23937/2643-4512/1710049

A Narrative Review of the Association between Pesticides, Organochlorines and Breast Cancer: Current Advances and Research Perspectives

Vinod K Ramani, MBBS, MD, MPH and Radheshyam Naik, MBBS, MD, DM

Article Type: Review Article | First Published: September 18, 2020

Incidence of breast cancer is steadily rising in the US. The role of estrogenic environmental contaminants such as the pesticide ‘Dichloro Diphenyl Trichloroethane (DDT)’ and the industrial products ‘polychlorinated biphenyls (PCBs)’ are gaining concern in recent years. Our study tries to draw inference by reviewing published research articles on this association. Pesticides may be classified as chemical carcinogens and they operate in a variety of ways. Some are mutagenic which interact...

 Open Access DOI:10.23937/2643-4016/1710021

Fibula Bone Graft Supporting Failed Posterior Rod Implants in Thoracic Spine Tuberculosis: A Case Report

Muath Mamdouh Mahmod Al-Chalabi and Wan Azman Wan Sulaiman

Article Type: Case Report | First Published: September 25, 2020

Tuberculosis of the spine is a challenging illness to treat because of the prolonged time of conservative treatment and the technical difficulties of surgical intervention. The disease remains a significant public health issue in developing countries but is also returning in developed countries due to immigration and particularly in immune-compromised patients. The most common symptom reported is back pain, and the most common segment involved; is the thoracic spine. One of the essential options...

 Open Access DOI:10.23937/2378-3656/1410319

Sigmoid Volvulus in Second Trimester is Challenge to Obstetric and Surgical Departments at St. Francis Referal Hospital, Kilombero, Tanzania

Theresia A. Karuhanga MD, MMED and Joseph M. Lulengo, MD, MMED

Article Type: Case Report | First Published: September 19, 2020

A 25 years Gravida 4, para 3, with 2 living at gestation age of 20 weeks who presented at St Francis Hospital with three days of colicky abdominal pain, associated with abdominal distension and constipation. Abdominal X-ray revealed a dilated large bowel and coffee bean sign while abdominal ultrasound showed a single living intrauterine fetus. Emergency laparotomy was done in which the findings revealed a gangrenous and twisted sigmoid at its mesenteric axis by 360 degrees. End to end anastomosi...