Open Access DOI:10.23937/2469-5769/1510074
Bacteremia in Pediatric Gastroenterology Patients with Central Venous Catheters Presenting to the Emergency Department
Courtney E Brennan, MD, Choo Phei Wee, MS, Jared Schiff, MD and Alan L Nager, MD, MHA
Article Type: Original Research | First Published: April 21, 2021
Medical records were retrospectively reviewed for gastroenterology patients presenting to a single, Pediatric Emergency Department with fever and a CVC from April 1, 2014 to December 31, 2016. The primary outcome measure is a positive blood culture. Additional variables studied include age, sex, history of prematurity, primary GI diagnosis, type of CVC and when it was inserted, the presence or absence of an enteral feeding tube, the use of total parenteral nutrition (TPN), weight, ED presenting ...
Open Access DOI:10.23937/2378-346X/1410125
Clinical features of the Anterior Chamber Depth
Miguel Angel Hernández-Delgado, MD, Sara Gonzalez Godínez, MD and Jorge Valdez-García, MD
Article Type: Review Article | First Published: April 19, 2021
To determine whether anterior chamber depth (ACD) has any clinical importance as well as the significance in various physiologic and pathologic processes. Anterior chamber depth has a direct proportional relation with axial length, corneal power and anterior chamber angle. It has an inverse proportional relation with age. Shallow anterior chamber depth was associated with and increased risk of endothelial cell density loss after phacoemulsification surgery, less ascorbic acid concentrations that...
Open Access DOI:10.23937/2378-3001/1410109
CGRP Monoclonal Antibodies for Prevention of Migraine: There are Many Adverse Effects
Lawrence Robbins
Article Type: Letter to the Editor | First Published: April 18, 2021
This letter is in response to the excellent July, 2020 article “Migraine and CGRP Monoclonal Antibodies: A Review of Cardiovascular Side Effects and Safety Profile” (Boldig and Butala). The package insert (PI) for the CGRP mAbs, as with many of the new drugs, identifies few AEs. The reasons for this include: 1. trial investigators did not use a checklist of AEs (a checklist is almost never utilized during drug trials) 2. As with most drug trials, the studies were powered for efficacy but wou...
Open Access DOI:10.23937/2378-2951/1410223
A Rare Case of Syncope Secondary to Sinus Node Dysfunction Associated with Brugada Syndrome
Maya Khodor, MD and Joseph Chattahi, MD
Article Type: Case Report | First Published: April 24, 2021
Brugada Syndrome is a rare arrhythmogenic entity that poses a risk of sudden cardiac death due to ventricular arrhythmias. Sinus node dysfunction is a less recognized and acknowledged conduction abnormality associated with Brugada syndrome, but nevertheless an important potential manifestation that can alter management. We present a case of a young patient who presented with syncope initially presumed to be secondary to a ventricular arrhythmia in the setting of newly diagnosed Brugada syndrome ...
Open Access DOI:10.23937/2469-5831/1510035
The Incidence of Tuberculosis in Brazil from 2001 to 2018: Use of Polynomial Regression Combined with a Stochastic Volatility Model
Jorge Alberto Achcar, Ricardo Puziol de Oliveira and Emerson Barili
Article Type: Original Article | First Published: April 21, 2021
Monthly tuberculosis (TB) counts from January 2001 to December 2018 showed an upward trend (data from SINAN - Information System for Notifiable Diseases). The increase in the incidence of TB in general is associated with an increase in the rate of extreme poverty, an increase in AIDS cases and other factors. Combining the polynomial linear regression and stochastic volatility models, the purpose of this study was to analyze monthly count data as well as the AIDS/TB, extreme poverty/TB and urban/...
Open Access DOI:10.23937/2690-3172/1710012
Intracerebellar Microinjection of an H4 Agonist Impairs Memory Consolidation in Open Field and Rotarod Tasks in Mice
C.E.M. Fernandes, E.M. Guilherme, K.R. Serafim, A.C.L. Gianlorenço and R. Mattioli
Article Type: Research Article | First Published: April 21, 2021
The cerebellum is known to participate in motor functions, but the role of the histaminergic system, and specifically the H4 receptors, in its functions is still unclear. In the present study, we investigated the effects of intravermis microinjections of an H4 receptor agonist (VUF-8430) on mice behavior undergoing a rotarod (Experiment 1) and open field (Experiment 2) test. The cerebellar vermis of male mice was implanted with a single guide cannula. All experiments were performed on two consec...
Open Access DOI:10.23937/2469-5823/1510157
Immunosuppressant Therapy Adherence after Kidney Transplantation
Ahmet Karaman, Yasemin Özhanli, Ezgi Seyhan-Ak, Seher Deniz Öztekin, Ertuğrul Göksoy, Nurhan Seyahi and Emel Şengül
Article Type: Research Article | First Published: April 21, 2021
Immunosuppressive therapy (IST) is administered to the individual to prolong the graft survival; thus, the survival of the patient after organ transplantation. Adherence of the individual to IST is crucial. In this study, it was aimed to find out patients’ adherence to immunosuppressant therapy after kidney transplantation. The sample of this descriptive study consisted of 50 patients; who underwent kidney transplantation in a university hospital in Istanbul and who applied to the hospital for...
Open Access DOI:10.23937/2469-5823/1510156
Mothers' Perception of Nursing Care of Hospitalized Children in Peadiatric Ward in a 3rd Level Facility in South-South Nigeria
Peretomode Evans, RN, RM, RPHN, B.N.Sc., MSc, Udo-Peretomode Eunice, RN, RM, RPHN, B.N.Sc., MSc and Diorgu Faith C, PhD, RM
Article Type: Research Article | First Published: April 21, 2021
Patient perception is an important indicator which gives an idea about the quality of nursing care services. Caregivers or family members who are responsible for the child’s stay in the hospital can play significant role in expressing their perception of the care provided to their relatives. This study assessed mothers’ perception of nursing care that exists in pediatric department of a teaching hospital in South-south, Nigeria. It also examined the association between mothers’ socio-demog...
Open Access DOI:10.23937/2469-5777/1510090
Timeline of Cross Finger Flap: From its Inception to its Future
Sourabh Shankar Chakraborty, DNB, MNAMS, Sudeshna Acharya, MBBS, Manojit Midya, MS, MCh and Ranjit Kumar Sahu, MS, MCh, FCLS
Article Type: Review Article | First Published: April 07, 2021
Since the first description of the cross-finger flap in 1950 for finger injury defect cover, over the last 70 years it has been tremendously explored and has underwent innumerable refinements and modifications. Whether used alone or in combination with other flaps for the reconstruction of finger defects, traumatic or non-traumatic, cross finger flap has proven its worth as a workhorse for finger reconstruction. Despite a handful of innate disadvantages, it has given excellent sensory, functiona...