Open Access DOI:10.23937/2378-3419/1410151

Assessment of Pivka II as Tumour Marker in Hepatocellular Carcinoma

Anuj Parkash, Parul Singla and Ashok Kumar Ahirwar

Article Type: Research Article | First Published: May 10, 2021

The most commonly used tumor marker in hepatocellular carcinoma (HCC) is serum alpha-fetoprotein (AFP). It has been routinely used for monitoring the prognosis of disease, but not for its detection. There is always a quest of new biomarkers for detection of HCC. The present study has been designed to determine the level of prothrombin induced by vitamin K absence-II (PIVKA II) in sera of patients suffering from HCC. The aim of this study is to evaluate the PIVKA II as a biomarker for HCC indepen...

 Open Access DOI:10.23937/2378-2951/1410224

Interatrial Block and Intermittent Paroxysmal Atrial Fibrillation in Amyotrophic Lateral Sclerosis Patient Treated with Flecainide

Athanassios Antonopoulos, MD, PhD, FESC and Giulia Ricci Lucchi, MD

Article Type: Case Report | First Published: May 05, 2021

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder affecting both upper and lower motor neurons. Cardiovascular consequences related to ALS are relatively under appreciated. Autonomic dysfunction in ALS is common. In fact, patients with ALS often exhibit bulbar dysfunction impacting centrally mediated vagal and sympathetic nerves with resultant greater autonomic dysfunction. The consequences of disruptions in the autonomic reflex loop on the cardiovascular system include chronot...

 Open Access DOI:10.23937/2469-5696/1410065

Evaluating Bone Mineral Density in Pediatric Acute Lymphoblastic Leukemia Survivors: A Tertiary Care Hospital Experience

Ersin Toret, Burcu Dural, Yeter Duzenli Kar, Zeynep Canan Ozdemir, Ilknur Ak Sivrikoz and Ozcan Bor

Article Type: Original Article | First Published: April 30, 2021

Acute leukemias are the most common malignancies seen in children and they account for one third of childhood cancers. Children who survived ALL, experience reduced bone mineral density (BMD) due to the disease, long-lasting glucocorticoid usage, chemotherapy toxicities, nutritional deficiencies and physical immobility. The decreased BMD have determined at all stages of disease. This retrospective cross-sectional study purposes to analyse the results of BMD in children who have completed their A...

 Open Access DOI:10.23937/2469-5696/1410064

COVID-19 and Aplastic Anemia: Friend or Foe

Mohd Mustahsin, Zeba Siddiqi, Ajay Mishra and Garima Singh

Article Type: Case Report | First Published: April 28, 2021

Aplastic Anemia is a rare hematological disorder caused by bone marrow failure leading to pancytopenia. These patients are frequently treated with immunosuppressive therapy which may protect them in developing hyper-inflammatory response which is commonly seen in moderate and severe COVID-19 patients. On the other hand these patients are at high risk for infection and infection related complications. Here we are reporting an adult aplastic anemia patient who developed uncomplicated course of COV...

 Open Access DOI:10.23937/2643-4512/1710056

COVID-19 Cover Pages May Cause Nocebo Effects on Public Health: First Observations on the Connection between Media and Health Data across Cultures

Joachim Grzega

Article Type: Original Article | First Published: May 10, 2021

Based on the observation that language use can harm health, the paper looks at the public health situation in late 2020 as compared to the situation in spring 2020 - the health situation is mainly defined via A) The weekly deaths 2020; B) The weekly deaths 2020 compared to the 2016-2019 average; C), The death rates measured as weekly z-scores at the national level, and as additional indicators; D) The death rates attributed to COVID-19; E) The intensive care unit days attributed to COVID-19; and...

 Open Access DOI:10.23937/2469-5823/1510158

Views of Nursing Students Who Have Experienced Caring for Psychiatric Patients on Mental Illness and Stigma: A Phenomenological Study

Ceyda Başoğul, RN, PhD

Article Type: Original Article | First Published: May 15, 2021

The phenomenological method was used in the study as the qualitative research design. The research was conducted with 23 students who completed the theoretical part of the psychiatric nursing course and its clinical practice in the nursing department of a university in Turkey. The data were collected through individual in-depth interviews and analyzed by content analysis method. In this study, the research efforts were continued until data saturation was achieved, and in this respect, the data s...

 Open Access DOI:10.23937/2643-4008/1710011

The Importance of Microorganisms and Their Effects on Medicinal Plants and Their Various Applications

Abdlmanam Fakron, Idress Hamad Attitalla, Mohamed Younes A Hassan and Sumeet Dwivedi

Article Type: Review Article | First Published: April 30, 2021

Since photosynthesis is the primary process through which light energy absorbed and converted into organic matter, thus, plant chlorophyll pigment (forms A and B) plays an essential role in the progression absorbed solar energy and synthesis of organic matter in a plant. Therefore, this paper aims at the extent to which the optical activity of chlorophyll molecules monitored and methods (non-destructive and destructive) for quantification of chlorophyll content in plants. These methods using to ...

 Open Access DOI:10.23937/2643-4466/1710033

Management of Uncontrolled Atrial Fibrillation in COVID Patient

Muhammad Zubair Khan, MD, Shaheer Zahid, MD, Sona Franklin, MD, Jamaluddin Saeed, MD, Vincent M Figueredo, MD, Steven Kutalek, MD and James Kilcoyne, DO

Article Type: Case Report | First Published: May 10, 2021

COVID-19 virus does not directly affect the heart. The virus can cause systematic inflammation that can lead to severe cardiac complications like uncontrolled atrial fibrillation (AF), which carries high mortality among patients. We present a case of an 82-year-old female from nursing home with advanced dementia and multiple comorbidities. She initially screened negative for COVID-19 in the nursing home, however her repeat test was positive. Soon after admission she developed progressive, hypoxi...

 Open Access DOI:10.23937/2378-3656/1410345

Characterization of Patients with Inguinal Hernia Ambulatory Surgical Treatment

Pedro Rolando Lòpez Rodrìguez, Olga Caridad Leòn Gonzalez, Jorge Satorre Rocha, Eduardo Castillo Garcia, Luis Marrero Quiala, M Elisa Puentes Rizo and Lais Angelica Ceruto Ortiz

Article Type: Original Article | First Published: April 30, 2021

The surgical treatment of inguinal hernia has increased in the last decade and its prevalence is not known. Objective: Characterization of patients with inguinal hernia ambulatory surgical treatment. An observational, descriptive and prospective study of 972 patients with the diagnosis of inguinal hernia was performed, which were operated on an outpatient basis in the General Teaching Hospital “Enrique Cabrera” since January 2009 to December 2020. Emergency operated patients were excluded. ...

 Open Access DOI:10.23937/2378-3656/1410344

The Rare Finding of Posteromedial Papillary Muscle Hypertrophy in Chronic Rheumatic Mitral Valve Disease

Ros Lavery, MB, BCh, BAO, MRCPI and David Kerins, FACC, FAHA, FESC, FASE

Article Type: Case Report | First Published: April 30, 2021

A scarcity of literature exists on papillary muscle hypertrophy. The reported incidence of 0.4% is based on a single study of 6731 patient echos that were reported in 1990. The importance of this condition is substantial as patients are often asymptomatic and it has been postulated as a potential cause of sudden cardiac death. A 43-year-old lady presented to our care that had an incidental finding of papillary muscle hypertrophy in the context of chronic rheumatic mitral valve disease. The clini...