Open Access DOI:10.23937/2474-3674/1510127
Use of Tranexamic Acid Prevents Intubation in ACE Inhibitor- Induced Angioedema
Ramzan Judge, Stephanie Kolaski and Farhan Qadeer
Article Type: Case Report | First Published: September 11, 2021
ACE-I, a common antihypertensive medication, regulates blood pressure by inhibiting angiotensinconverting enzyme (ACE). This inhibition prevents the formation of angiotensin II from angiotensin I, a peptide hormone that causes vasoconstriction. ACE is also involved in the degradation of bradykinin, a potent mediator of vasodilation. When ACE is inhibited, the arteriolar smooth muscle relaxes and increases blood flow, leading to increased vasodilation of blood vessels, vascular permeability, and ...
Open Access DOI:10.23937/2378-2951/1410238
Correlation between Self-Reported Daily Activity and Submaximal Walk Test in the Assessment of Functional Capacity among Patients with Hypertension
Tolulope O Olatunbosun, MSc PT, Taofeek O Awotidebe, PT, PhD, Rufus A Adedoyin, PT, PhD, Olufesola M Fasakin, RN, MSc, Suraj A Ogunyemi, MBChB, FWACP, Abayomi A Olawoye, PT, DPT and Adekola J Odunlade, MSc, PT
Article Type: Original Article | First Published: September 13, 2021
Time constraint on the part of clinicians or musculoskeletal comorbidities in the lower limbs in some patients with hypertension may sometimes prevent submaximal walk test. Hence, self-reported activity thus becomes an alternative method for assessing quick functional capacity (FC). This study assessed FC using a self-reported daily activity tool; Duke Activity Status Index (DASI) and correlated its value with 6-Minute Treadmill Walk (6-MTW) among patients with hypertension. This cross-sectional...
Open Access DOI:10.23937/2378-2951/1410237
A Case of a Large Coronary Artery Fistula
Yevgeniy Latyshev, MD
Article Type: Case Report | First Published: September 11, 2021
Coronary artery fistulas are rare anomalies found during coronary angiography and non-invasive cardiac imaging. Recent advances in understanding of the pathophysiology allow more effective surgical and percutaneous treatments. It is important to recognize and treat hemodynamically significant fistulas when appropriate before ischemia and or heart failure occurs. We present a case of coronary artery fistula that was treated conservatively after a heart team discussion. Coronary artery fistulas (C...
Open Access DOI:10.23937/2469-5696/1410068
Diagnostic Value of miR-26b in Schizophrenia
Ling-ming Kong, Xiao-li Zhu and Li-yi Zhang
Article Type: Original Article | First Published: September 22, 2021
This study aimed to investigate the diagnostic value of peripheral microRNA (miRNA) expression in schizophrenia (SZ). By using an Affymetrix array to identify differentially expressed miRNAs in SZ patients; quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) was used to verify identified microRNA and test major depressive disorder (MDD), generalized anxiety disorder (GAD) and mental retardation (MD) related microRNAs for comparison. The expression levels of miR-1972...
Open Access DOI:10.23937/2572-407X.1510026
Graves Thyrotoxicosis and Cerebral Venous Sinus Thrombosis Causality or Chance Alone?
Richmond Ronald Gomes
Article Type: Case Report | First Published: September 22, 2021
Cerebral Venous Sinus Thrombosis (CVST) is a rare cerebrovascular condition accounting for 0.5-1% of all types of strokes in the general population and 12.5% of cases are considered to be idiopathic. Hypercoagulability, local bloodstream stasis, and vessel wall abnormalities may contribute to the development of this condition. The thyrotoxic phase of Graves’ disease is associated with venous thrombosis caused by hypercoagulability, which is in turn induced by increased levels of homocysteine a...
Open Access DOI:10.23937/2572-3987.1510027
Effect of Various Activation of the Skin TRPA1 Ion Channel on Cardiovascular Systemic Parameters in Hypertensive Rats
TV Kozyreva and ES Meyta
Article Type: Research Article | First Published: September 16, 2021
The effect of different activation of the skin TRPA1 ion channel on the parameters of the cardiovascular system was studied in rats with hereditary stress-induced hypertension while recovery from anesthesia. The activation of the TRPA1 ion channel was performed by application to skin its agonist - allyl isothiocyanate (AITC) in two concentrations 2.5% and 0.5%. The following parameters were measured that characterize the work of the cardiovascular system: Blood pressure (systolic, diastolic, and...
Open Access DOI:10.23937/2474-3682/1510184
A Guide for Identification of Ulcers of the Lower Limb
Alhad Mulkalwar, Apoorva Doshi and Samir Deolekar
Article Type: Image Article | First Published: September 18, 2021
An ulcer is defined as a breach in the continuity of the skin or a mucous membrane with molecular death of the cells due to underlying inflammation. Figure 1 depicts the different parts of an ulcer. The article describes four different types of ulcers of the lower limb commonly encountered in the surgical wards, with their major characteristics and markers of identification. There are certain distinct features to identify the trophic ulcer in Figure 2 on visual inspection. The location of the ul...
Open Access DOI:10.23937/2474-3682/1510183
Vesico-Vaginal Fistulae
Benatta Mahmoud
Article Type: Image Article | First Published: September 18, 2021
42 years deaf virgin female consulted for urine permanent leakage through vagina. She had gynecologic surgery six months ago for uterine fibroids. Classic physical examination was limited. Digital touch and speculum and by methylene blue test, was not performed because the patient and her family did not agree. Diagnosis of vesico-vaginal fistula made mainly by radiology imaging (Figure 1 and Figure 2). Retrograde and mictionnal uretro-cystography showed a clear leakage of contrast from the bladd...
Open Access DOI:10.23937/2474-3682/1510182
A Giant Bladder Stone in a Young Woman Complicated with Acute Renal Failure
Richepin TIDAHY, Ali KHAYAT, Oussama BENABDELHAK, Mustapha AHSAINI, Soufiane MELLAS, Jalal Eddine EL AMMARI, Mohammed FADLTAZI, Mohammed Jamal EL FASSI and Moulay Hassan FARIH
Article Type: Image Article | First Published: September 16, 2021
Bladder stones are an uncommon condition in women and according to the literature, less than 2% of all bladder stones occur in women. This condition is often overlooked because of its rarity, hence the diagnostic and therapeutic delay which can lead to potentially serious complications. Its treatment is essentially surgical and the choice between endoscopic, laparoscopic or open surgery methods depends mainly on the size of the stones and its etiology. In women, the occurrence of urinary bladder...