Open Access DOI:10.23937/2378-3656/1410459
Anaesthesia Challenge: Kasai's Portoenterostomy in a CMV Positive Infant with Tetralogy of Fallot and Biliary Atresia
Aakriti Sharma, Pavan Gaurav, Neelam Dogra, Pratibha Rathore and Rama Chatterjee
Article Type: Case Presentation | First Published: 2024/10/31
Biliary atresia is a multifactorial neonatal disorder affecting the extrahepatic bile ducts leading to cholestatic jaundice and eventual liver transplantation. The most frequent viral infection linked to biliary atresia is CMV. It has not yet been documented that Tetralogy of Fallot, a common cyanotic congenital cardiac defect, is connected to BA. An unusual feature of the case is the rare combination of cytomegalovirus infection, tetralogy of Fallot, and biliary atresia....
Open Access DOI:10.23937/2474-3682/1510244
Idiopathic Calcinosis of the Scrotum
Youssef Zemmez, Amine Ennaciri, Abdourahman Moussa, Rachid Frikh and Naoufal Hjira
Article Type: Image Article | First Published: 2024/11/06
This was a 35-year-old patient with no previous pathological history who had been presenting with a pruritic, painless, progressively enlarging scrotal swelling since the age of 30. On examination, the lesions were multiple, nodular, mobile in relation to the deep plane, confluent, non-inflammatory and overall measuring 4 cm/1 cm (Figure 1). The nodules contained a thick, whitish fluid. The testicles and epididymides were clinically normal. Surgical excision was performed under local anaesthetic...
Open Access DOI:10.23937/2378-3672/1410074
Role of Immune Components and Immunotherapy in Prostate Cancer Treatment
Pradeep Kumar and Sujeet Kumar Mewar
Article Type: Review Article | First Published: 2024/11/04
Prostate cancer (PCa) is a prevalent malignancy among men, with advanced stages often presenting significant treatment challenges despite traditional therapies such as surgery, radiation, and hormone therapy. Recent advancements in immunotherapy have introduced new strategies to harness the immune system's potential in combating this disease. This review explores the roles of various immune components in PCa and evaluates the impact of emerging immunotherapeutic approaches. Immune components, in...
Open Access DOI:10.23937/2572-3235.1510128
Uncommon Neoplasms in a Common Location: Primary Hepatic Neoplasms - A Pictorial Review
Jayaranjeetham Jayabalan, Madhan Ramachandran, Sunitha Vellathussery Chakkalakkoombil and Revathy Ganapathy
Article Type: Review Article | First Published: 2024/11/04
Common hepatic lesions are easy to diagnose and various imaging methods are available for those lesions. Uncommon hepatic lesions pose a diagnostic challenge to the radiologist. In our study we have described the common imaging (Contrast enhanced Computed Tomography-CECT and Magnetic Resonance Imaging-MRI) appearances of the uncommon hepatic lesions which are proven with histopathology. We described about few of the uncommon hepatic lesions like Hepatic lymphoma, Liver neuroendocrine tumor (NET)...
Open Access DOI:10.23937/2469-5807/1510157
Metastatic Lobular Carcinoma Involving the Vulva as Initial Presentation of Disease in a Patient with Dense Breast Tissue
Shandice Waugh, Michael Deavers and Lavinia P. Middleton
Article Type: Case Report | First Published: 2024/11/03
We present the case of a 72-year-old woman with dense breast tissue and no initial mammographic signs of malignancy, who presented with a vulvar mass that was discovered to be metastatic lobular carcinoma from the breast. This is the first example documented in the English literature of metastatic lobular carcinoma involving the vulva as the initial presentation of disease. This case report highlights the pathologic features of this uncommon entity and its diagnostic challenges....
Open Access DOI:10.23937/2469-5858/1510157
The State of Frailty Research in Arabic-Speaking Countries: A Scoping Review
Amany Aly, Stephanie J. Kendall, Stefan S. Heinze, Chris MacKnight, Olga Theou, Susan Bowles and Scott A. Grandy
Article Type: Review Article | First Published: 2024/10/31
Frailty is an age-related decline in function and reserve in one or more physiological systems, which increases the risk of poor health outcomes, hospitalization, and death. Although frailty has been well studied in developed countries, little is known about the state of frailty research in Arabic-speaking countries (ASCs)....