Open Access DOI:10.23937/2469-5734/1510167
Radiographic Evaluation of Developmental Dental Anomalies in Children Attending Dental Hospital Peradeniya-Sri Lanka
Herath Mudiyanselage Imali Maheshika Udayangani, BDS, Ginigal Godage Harindu Upulitha, BDS, Virajini Uthayakumar, BDS, Lokuappu Kuttige Nadeesha Premathilaka, BDS, MD and Ekanayake Mudiyanselage Udagedara Chandra Kumari Herath, BDS, MD, FDSRCS
Article Type: Research Article | First Published: 2024/10/10
Developmental dental anomalies are changes in the dental structure. These anomalies include the changes in shape, size, number, tissue structure, and position of teeth. Dental panoramic radiograph remains the gold standard for the early detection of such anomalies....
Open Access DOI:10.23937/2469-567X/1510095
Virologic Efficacy of Recycling Tenofovir and Lamivudine/Emtricitabine in Second-Line Antiretroviral Treatment with Dolutegravir: A Non-Inferiority-Matched Cohort Study in Senegal
Bruce Shinga Wembulua, Daye KA, Viviane Marie Pierre Cisse, Ndeye Fatou Ngom, Ahmadou Mboup, Ibrahima Diao, Aminata Massaly, Kalilou Diallo, Mouhamadou Baila Diallo, Junior Latyr Diouf, Jonas Kombila, Moustapha Diop, Papa Samba BA, Noël Magloire Manga, Stanislas Okitotsho Wembonyama, Zacharie Kibendelwa Tsongo and Moussa Seydi
Article Type: Original Article | First Published: 2024/11/14
The World Health Organization (WHO) now recommends dolutegravir (DTG)-based regimens as the preferred option for first-line and second-line antiretroviral therapy (ART) for all people living with HIV (pwHIV). However, exposure to tenofovir (TDF) in first-line antiretroviral therapy (ART) could compromise its efficacy (K65r mutation). Our study aimed to assess whether recycling TDF and lamivudine or emtricitabine (XTC) with DTG as second line ART is non-inferior to optimized nucleotide reverse t...
Open Access DOI:10.23937/2378-3419/1410190
Smoking Effects on Serum Hepcidin Levels in Breast Cancer Patients: A Cross-Sectional Study
Zein Al-Abideen Douba and Rama Ibrahim
Article Type: Original Article | First Published: 2024/11/11
Breast cancer remains a leading cause of cancer-related morbidity and mortality among women worldwide. Hepcidin, a central regulator of iron metabolism, has emerged as a potential biomarker in cancer biology and a predictive agent of recurrence. As smoking represents a risk factor in developing many types of cancer, this article discusses the possibility of the effect of smoking on hepcidin levels in women diagnosed with breast cancer....
Open Access DOI:10.23937/2643-4016/1710041
Charcot Arthropathy in the Lumbar Spine: Case Report
Cesar David Hernandez-Lira, Carlos Alberto Carreon-Cerda, Antonio Alejandro Ortiz-Mendez and Mario José Lezama-Peniche
Article Type: Case Report | First Published: 2024/11/10
Charcot arthropathy of the spine is a process in which the stability of the spine is affected due to joint involvement, causing joint destruction, pain and deformity. The most frequently associated cause is trauma, conservative treatment is an option depending on the characteristics of each patient, and surgical treatment, if indicated, can represent a real challenge for the orthopedist due to the instrumentation techniques that are generally needed....
Open Access DOI:10.23937/2643-4016/1710042
Posterior Tibial Tendon Transfer in Bilateral Foot Drop: Case Report
Carlos Carreon-Cerda, Mario Lezama-Peniche, Victor Alayon-Vazquez, Adrian Chan-Cisneros, Alejandro Ortiz-Mendez and Cesar Hernandez-Lira
Article Type: Case Report | First Published: 2024/11/10
15-year-old female patient with a history of congenital common peroneal nerve paralysis. The first surgical stage is performed on the left foot, tendon transfer is performed with the classic Barr's technique, the posterior tibial tendon is disinserted by crossing the interosseous membrane and inserting in a lateral cuneiform. The second surgical procedure was performed 9 months after the first surgery with tendon transfer of the right foot, the procedure began with the classic Barrs technique, w...
Open Access DOI:10.23937/2572-4142.1510011
A Theoretical Construct Advocating Exploration of the Converging Immunomodulating Pathways in Suicide and Behçet Disease
Zaid Naseer, MD, Minaal Khan, DO (2026), Najeeb Manalai, MD, Gul PM Osmani, MD, Allison Foroobar, MD, Daniel Nicholas, DO, Patricia Harrison, MD, Donna Carmosky, MD, Charles Scercy, MS, Beth Yanoff, MD and Partam Manalai, MD
Article Type: Review Article | First Published: 2024/11/09
Suicide is a global public health challenge, with approximately a million people losing their lives to suicide annually. The study of suicide and understanding and the neurobiology of suicide have remained challenging However, focusing on specific illnesses and pathways may aid in providing a better understanding of the neurophysiology of suicide. For example, Postolache, et al. have extensively reported on Toxoplasma gondii and suicidal behaviors. In this paper, we reflect on the role of immuno...
Open Access DOI:10.23937/2643-4563/1710057
The Role of Hepcidin Levels in Colorectal Cancer Patients
Lara Khalil and Rama Ibrahim
Article Type: Original Article | First Published: 2024/11/09
Colorectal cancer is a worldwide health issue with high-cost treatment process. Several experimental studies have clarified the role of Hepcidin as a new reliable marker that helps to predict colorectal cancer development and prognosis. Our study Aims to measure Hepcidin levels in patients diagnosed with colorectal cancer, study the importance of Hepcidin levels and its correlation with recurrence....
Open Access DOI:10.23937/2469-5807/1510159
Adenoid Cystic Carcinoma of Thyroid - Unusual Primary Site and Diagnostic Considerations in Cytology
Vijayalakshmi Gudivada, MD, DipFRCpath, Parepalli Divya, MD, Pampa ch Toi, MD and Sreekanth Gaddam, MBBS, MSc
Article Type: Case Report | First Published: 2024/11/08
Adenoid cystic carcinoma (ACC) is a rare head and neck tumor, typically arising from both major and minor salivary glands and sweat gland epithelium. This case report presents a 38-year-old female with primary thyroid ACC, an exceedingly rare entity with only a very few cases reported in the literature. The patient presented with a solitary thyroid nodule, Fine needle aspiration cytology revealed basaloid cells in three-dimensional clusters with many luminal hyaline globules, consistent with ACC...
Open Access DOI:10.23937/2474-3682/1510245
Safeguarding Patient Care: Why Pre-Use Anesthesia Equipment Checks are Essential
Sanjay Aamat, MD and Abhishek Singh, MD
Article Type: Clinical Image | First Published: 2024/11/08
Given the increasing emphasis on quality standards in healthcare, a structured, comprehensive checklist aligns with guidelines from professional organizations like the American Society of Anaesthesiologists (ASA) and the World Health Organization (WHO). Not only does it improve patient outcomes, but it also streamlines workflow, enhances team communication, and helps build patient confidence in the safety of anesthesia practices. In light of these benefits, implementing a thorough pre-use anesth...