Open Access DOI:10.23937/2474-3658/1510233
A Randomized Controlled Trial of Ivermectin Monotherapy versus Hydroxychloroquine, Ivermectin, and Azithromycin Combination Therapy in COVID- 19 Patients in Nigeria
Babalola OE, Ndanusa YA, Ajayi AA, Ogedengbe JO, Thairu Y and Omede O
Article Type: Randomised Drug Trial | First Published: October 31, 2021
The efficacy of Ivermectin (IVM) against SARS-CoV-2 has been demonstrated in vitro, while several clinical studies suggest that it is efficacious and safe in reducing morbidity and mortality. Hydroxychloroquine (HCQ, Quinoric®), IVM and Azithromycin(AZM, Zithromax®) (HIA therapy) is being used in several low- and middle-income countries (LMIC) where more expensive medications such as Remdesivir are out of reach. In this study, we set out to compare the efficacy of IVM monotherapy with HIA comb...
Open Access DOI:10.23937/2474-3658/1510232
Sex-Specific Differences in the Short-Term Prevalence Trends of HIV and HBV among Undergraduate Nigerians: Implications for Policy
Henry E Aloh, Sharon O Azubuike-Osu, Cletius Nwabuogu, Miriam Nwankwo and Chukwunonso ECC Ejike
Article Type: Original Article | First Published: October 30, 2021
The prevalence of Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV) infections and their co-infection are rarely reported among undergraduate Nigerians. This study sought to provide data in the said direction and discuss policy imperatives. A population of 4,876 undergraduate students of the Alex Ekwueme Federal University, Ndufu-Alike (AEFUNAI), Nigeria (52.7% females; mean age: 20 ± 2 yrs, females; 20 ± 3 yrs, males) was studied. Standard procedures were used for collection and ...
Open Access DOI:10.23937/2474-3658/1510231
Predictors of Pulmonary Cavitation among Tuberculosis Patients
Oluwafemi O Balogun, Adetayo Fawole, Etiosa Osemwinyen and Busola Balogun
Article Type: Original Article | First Published: October 30, 2021
Globally, Tuberculosis (TB) remains one of the top ten causes of mortality. Furthermore, the incidence and prevalence of the disease spectrum remain high in lowand some middle-income countries. Due to the associated high morbidity and mortality, the World Health Organization (WHO) declared it a public health emergency. Furthermore, pulmonary cavitation, classified epidemiologically and clinically as the hallmark of TB, has been associated with increased bacillary burden, high infection transmiss...
Open Access DOI:10.23937/2469-5750/1510111
Diagnostic Accuracy amongst Two Week Wait Referrals for Skin Malignancy
Ayda Haile-Redai and Johanna O’Connor
Article Type: Original Article | First Published: November 10, 2021
The two week wait pathway initiative was proposed in 1997 to expedite referrals from general practice to dermatology and to facilitate access to timely treatment for patients with suspected skin malignancy. However, since its implementation it has come under fire for its poor specificity and case detection rate with dermatologists raising concerns about their increased workload and consequently lack of time for other urgent cases. The present study conducted at Queen’s Hospital, London aimed t...
Open Access DOI:10.23937/2469-5750/1510110
Knowledge, Attitude and Practice toward Pruritus Management among Physicians and Patients Living With Diabetes Mellitus: A Quantitative Survey in India
Sanjay Kalra, Asit Mittal, Roheet M Rathod, Colette Pinto, Rahul Rathod and Amey Mane
Article Type: Case Report | First Published: November 10, 2021
Pruritus is a common dermatological condition which may have systemic etiology. Diabetes is one such condition; pruritus is commonly seen in patients with diabetes thus making it a dermatometabolic condition. The present survey aimed to understand the knowledge, attitude, and practice toward pruritus among Indian physicians and patients living with diabetes presenting with pruritus. A telephonic, cross-sectional, quantitative survey was conducted among consulting physicians (CPs), endocrinologis...
Open Access DOI:10.23937/2469-567X/1510079
Antibody Response to SARS-CoV-2 in HIV Patients Co-Infected with COVID-19
Rumpa Saha, Alpana Raizada, Pooja Dewan, Kirti Nirmal, Vikas Saini, Amir Maroof Khan, Narender Singh Mogha, Shweta Jain, Sunil Gomber and Narender Pal Singh
Article Type: Original Research | First Published: October 30, 2021
As the spike protein of the SARS-CoV-2 envelope has been shown to be highly immunogenic and is the main target for neutralizing antibodies, the present pilot study aimed to evaluate the IgG antibody response to SARS-CoV-2 spike protein in HIV seropositive patients coinfected with COVID 19. This cohort study was carried out in Delhi with HIV seropositive patients infected with COVID -19 whose 6 consecutive blood samples were collected after a gap of every 15 days starting at day 20 post Covid-19 ...
Open Access DOI:10.23937/2643-461X/1710054
Human African Trypanosomiasis in the Northern Region of Zimbabwe: Reported Cases, Health Implications and the Way Forward
Amon Munyenyiwa, Moses Zimba, Mascelini Jenipher Mutsaka-Makuvaza, Portia Manangazira, Tamuka Nhiwatiwa, Charles Maponga and Nicholas Midzi
Article Type: Review Article | First Published: November 10, 2021
Human African Trypanosomiasis (HAT) keeps resurfacing in Zimbabwe raising the need to capacitate the health system with adequate tools to eliminate the disease as a public health threat in the country. The aim of this study is to document recorded HAT cases in Zimbabwe as well as highlighting the impact of the disease and potential control strategies. Published research articles with main focus on HAT in Africa and Zimbabwe were used. The country recorded zero cases of HAT from 1998 to 2004, con...
Open Access DOI:10.23937/2572-4037.1510053
International Survey of Negative and Positive Reactions to Psychoanalytic Distance Treatment at the Beginning of the Pandemic
Robert M Gordon, PhD, Zhenyu Shi, MD, PhD, David E Scharff, MD, Ralph E Fishkin, DO, and R Dennis Shelby, MSW, PhD
Article Type: Empirical Research | First Published: October 30, 2021
We conducted an international survey to better understand both the negative and positive reactions of distance treatment during the pandemic. We received 1,490 survey responses from practitioners from 56 regions and countries who remotely treated patients psychoanalytically during the beginning months of the Covid-19 pandemic. Eighty-nine percent of the practitioners agreed or strongly agreed that distance treatment is valuable when the patient is housebound or when travel would be difficult or ...
Open Access DOI:10.23937/2643-4512/1710067
Incidence and Associated Risk Factors of Hypertension among HIV Patients on Antiretroviral Therapy in Fako Division: A 5-Years Retrospective Cohort
Tah Aldof Yoah, Tendongfor Nicholas, Njukang Ernest Nkem, Kah Emmanuel Nji, Ndale Sylvanus Akonwei, Nde Fon Peter, Enow Orock George and Anna Longdoh Njunda
Article Type: Research Article | First Published: November 05, 2021
The aim of this study was to determine incidence and associated risk factors of hypertension among HIV patients on antiretroviral therapy (ART) in Fako Division, South West Region of Cameroon. A 5-years retrospective cohort study was used to review the records or patient files of 1640 HIV patients enrolled between the years 2013-2015. These files were reviewed in 3 HIV treatment Centers which measured a recorded blood pressure routinely. Data was entered in SPSS 25 and analyzed using stata 13. L...